HOME >> MEDICINE >> NEWS
Physicists study mad cow-type diseases

Using math and physics to investigate mad cow disease (bovine spongiform encephalopathy or BSE) and similar diseases caused by infectious proteins called prions is the aim of research by physicists Daniel Cox, Rajiv Singh and colleagues at UC Davis. The researchers are using mathematical models to study issues such as the incubation time, prion "strains" and treatment or detection strategies.

Diseases such as BSE in cattle, Creutzfeld-Jakob disease in humans and chronic wasting disease in deer are all apparently caused by prions, misfolded versions of a normal brain protein. Similar diseases have been found in other animals including cats, mink and rodents, and prion-type proteins have even been found in yeast.

Prions seem to cause disease by triggering normal versions of the same protein to spontaneously fold up the wrong way, creating growing mats and tangles.

The UC Davis researchers have developed mathematical models to simulate this process. The models reproduce how prions collect around an original "seed" prion, and how these clumps subsequently break up and spread around the brain and nervous system.

Predictions from the models compare well with the course of actual disease in both small and large animals, Cox said.

Cox and colleagues are now using the model system to investigate the minimal requirements for prions to cause disease; how "strains" of prions can exist and what effect they have; and potential treatment strategies.


'"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
23-Jan-2004


Page: 1

Related medicine news :

1. Physicists find patterns within seemingly random events of physiological systems
2. First head-to-head study to compare lidoderm patch and Celebrex in treating pain
3. UMaine study looks at infants and chronic nighttime crying
4. Chronic pain treatments more effective when taken together, new study shows
5. UNC study: Most N.C. family practitioners engage in unrecognized community service
6. New study in Nature demonstrates protection against cell death during heart attack
7. UCSF study offers insight into human circadian rhythms
8. International breast cancer prevention study launches in the United States and Canada
9. UW study shows blacks and Latinos are more satisfied with physicians of the same race
10. Physicians may not be accurate in their confidence levels of their diagnoses, says Pitt study
11. Advertising by academic medical centers may risk eroding public trust, says study

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Physicists study mad cow type diseases

(Date:12/22/2014)... (HealthDay News) -- U.S. and state health officials are ... has killed at least four people and sickened 28 ... any commercially produced, prepackaged caramel apples until more information ... Prevention said in a news release. As of ... infected with the outbreak strains of the bacteria ...
(Date:12/22/2014)... (PRWEB) December 22, 2014 Explorys, the ... additions to its leadership team: Greg Yarrington as Vice ... Engineering, and Patrick Wells as Vice President of Solutions. ... add 80 new jobs in 2015 to support client ... of its platform-as-a-service offerings, and growth of its partner ...
(Date:12/22/2014)... 22, 2014 Pasadena sleep apnea ... for sleep apnea. Drowsy drivers are 15 times more ... are well-rested, and some experts believe that sleep-deprived drivers ... intoxicated drivers. Unfortunately, millions of Americans may be sleep-deprived ... of Sleep Medicine, about 18 million Americans have sleep ...
(Date:12/22/2014)... 2014 Christmas is days away, and last ... and easy solution that will please: the Sublime Gift ... from from $25 up to $350," says Kathy Heshelow, founder ... and a wide array of skin care products and Skin ... expiration dates. , Gift delivery past shipping deadlines, or ...
(Date:12/22/2014)... At the annual National ... in San Antonio, esteemed experts and thought leaders ... stand in the way of successful organizational performance: ... premier faculty development opportunity is made possible through ... is to assist nurse educators to advance to ...
Breaking Medicine News(10 mins):Health News:CDC Warns of Listeria Danger From Caramel Apples 2Health News:Explorys Continues to Experience Rapid Growth, Adds Three Healthcare IT Executives to Its Leadership Team 2Health News:Explorys Continues to Experience Rapid Growth, Adds Three Healthcare IT Executives to Its Leadership Team 3Health News:Pasadena Dentist, Dr. Marine Martirosyan, Now Offers Consultations for Sleep Apnea 2Health News:2015 NLN Leadership Conference February 5-7 San Antonio 2Health News:2015 NLN Leadership Conference February 5-7 San Antonio 3
(Date:12/22/2014)... --  TRU-D SmartUVC LLC, producers of the first ... that the General Services Administration has awarded the company ... This newly formed agreement will allow TRU-D SmartUVC ... including Department of Veteran Affairs and Department of Defense ... solutions for the Ebola effort in West ...
(Date:12/22/2014)... Cyberonics, Inc. (NASDAQ: CYBX ), a ... of epilepsy, today announced it will participate in the 33 ... 14, 2015, in San Francisco . ... Officer, will speak at 11:00 AM Pacific Time.  A live ... on the Investor Relations link on the Cyberonics home page ...
(Date:12/22/2014)...  Mark Farrah Associates (MFA), www.markfarrah.com , ... the 2015 marketplace exchange projections and insights about ... According to a recent ASPE (Office of the ... Health and Human Services) report, an estimated 6.7 ... through the Marketplace as of October 2014 and ...
Breaking Medicine Technology:TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2Insights into the Marketplace and Individual Market Growth 2
Cached News: