HOME >> MEDICINE >> NEWS
Pioglitazone HCI shown to lower blood pressure in hypertensive patients with type 2 diabetes

Orlando FL, June 5, 2004 Type 2 diabetes and hypertension are commonly associated conditions, both of which carry an increased risk of cardiovascular disease. Results of a large, open-label, multi-center, observational clinical trial show that treatment with the oral anti-diabetic agent pioglitazone HCl in people with type 2 diabetes has beneficial effects in reducing hypertension. The findings were presented today at the American Diabetes Association's 64th Annual Scientific Sessions.

In a study of 3,140 hypertensive patients with type 2 diabetes, all patients received open-label pioglitazone (30 mg/day) for 16 weeks. Hypertension was classified according to current National Institutes of Health guidelines (JNC VII): Stage I: 140-159/90-99 mmHg; Stage II: >160/>100 mmHg. Among patients with Stage I hypertension, pioglitazone elicited a mean decrease of 6.9/3.1 mmHg compared to baseline. In the patients with more severe, Stage II hypertension, pioglitazone was associated with a decrease of 18.7/8.3 mmHg.

"Although increasing clinical evidence suggests that drugs such as pioglitazone have blood pressure lowering effects, until now, those results had not been confirmed in large, unselected patient populations," noted lead investigator Thomas Konrad, M.D., Ass.Prof. Institute for Metabolic Research, Frankfurt, EU RISC- Study Center. "The importance of treating hypertension in patients with type 2 diabetes is particularly crucial because of the high incidence of elevated blood pressure in people with diabetes. A major government study found that almost 80 percent of patients with diabetes also have hypertension, thereby compounding their cardiovascular disease risk. These blood pressure-lowering findings are remarkable, because they suggest that pioglitazone may be able to impact certain cardiovascular disease risk factors in patients with type 2 diabetes."

In patients with type 2 diabetes, management of risk factors beyond diabetes
'"/>

Contact: Julio Cantre
julio.cantre@ketchum.com
646-935-4122
Ketchum
6-Jun-2004


Page: 1 2

Related medicine news :

1. Pioglitazone shown to reverse thickening of carotid artery wall
2. Cartilage repair techniques shown to restore patient mobility and reduce pain
3. Sprinklers shown effective in slowing dorm fires
4. Controversial drug shown to act on brain protein to cut alcohol use
5. HPV vaccine shown effective at reducing cancer-causing infections
6. HPV vaccine shown to substantially reduce cervical cancer
7. New research results: Heart jacket shown to be effective
8. Isolated soy protein shown to benefit type 2 diabetics, study indicates
9. Increased risk of cardiovascular disease shown in PCOS patients
10. Combination therapy w/ ACTOS (pioglitazone HCI) shown to improve components of diabetic dyslipidemia
11. Anti-eosinophil therapy shown to be effective in treating hypereosinophilic syndrome

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun ... NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is ... is geared towards children of all ages; it is a non-competitive, non-timed event, which ...
(Date:10/13/2017)... ... ... On The Brink”: the Christian history of the United States and the loss of ... William Nowers. Captain Nowers and his wife, Millie, have six children, ten grandchildren, ... Navy. Following his career as a naval aviator and carrier pilot, he spent ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... ... October 12, 2017 , ... HMP , a leader in healthcare events ... Magazine Eddie Digital Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the ... The annual award competition recognizes editorial and design excellence across a range of sectors. ...
(Date:10/12/2017)... ... October 12, 2017 , ... In the United ... year. In some states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and ... havens have extremely low property-tax rates, which contributes to the relatively lower cost ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... , Oct. 12, 2017   Divoti USA ... Jewelry up to the standard of the latest FDA requirements, which ... 2017). Anyone in need of Medical ID jewelry such ... Alert Jewelry are engraved in terms of the new ... Divoti offers ...
(Date:10/11/2017)... Oct. 11, 2017  True Health, a leader ... its effort during National Breast Cancer Awareness month ... risks. Research ... calculated that more than 10 million American women ... in BRCA1 or BRCA2 and have not had testing. ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
Breaking Medicine Technology:
Cached News: