HOME >> MEDICINE >> NEWS
Popular anti-epileptic drug also effective in controlling debilitating symptom of multiple sclerosis

A study published in the December issue of Archives of Neurology and currently available online shows that levetiracetam reduced phasic spasticity, which is marked by spasms and painful muscle cramps, in 100 percent of patients in a small clinical study.

"It's amazing how many MS patients can't walk, can't move, and you treat their spasticity and they're fine," said Dr. Kathleen Hawker, assistant professor of neurology at UT Southwestern and lead author of the study. "What's nice about these drugs is that they also work for nerve pain, which in turn improves the patient's mood, so we can use one drug for three things instead of prescribing pain killers and antidepressants in addition to the spasticity therapies."

Spasticity is often seen in patients with MS and amyotrophic lateral sclerosis (ALS), as well as after a stroke or spinal-cord injury. It can lead to loss of balance, increased risk of falls, pain, fatigue, and walking difficulties.

Drugs currently used to treat spasticity may cause memory problems, weakness and lethargy in some patients.

"We're trying to look at medicines that can be used for multiple symptoms so we don't get into a lot of drug interactions," Dr. Hawker said. "If we can get the same results with a better-tolerated drug, that's great for our patients."

Researchers examined the histories of 11 patients treated with levetiracetam between January 2001 and June 2002 for MS-related spasticity at Southwestern Medical Center. The patients were treated with levetiracetam for one to four months, with dosages starting at 250 milligrams per day and increasing to 3,000 mg per day. Researchers found that leviteracetam decreased phasic spasticity in patients taking the drug alone as well as in those who took it in combination with other therapies for spasticity. Tonic spasticity, which produces stiffness, did not improve. Overall, the clinical investigators found the side effects of levetiracetam to be gener
'"/>

Contact: Rachel Horton
rachel.horton@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
15-Dec-2003


Page: 1 2

Related medicine news :

1. Popular chewing gum eliminates bacteria that cause bad breath
2. Popular drug for chest pain may promote blood vessel damage
3. Popular long-acting contraceptive linked to vascular dysfunction
4. Popular asthma drug inadequate when used alone, new study shows
5. Popular herbal remedy fails effectiveness test for tinnitus
6. Popular notions about breast cancer-psychology link challenged
7. Sexually Oriented Internet Sites Are Popular And Non-Problematic For Most People, But Pose Risks For Some
8. UCSF Study Finds Popular Blood Thinner Does Not Weaken Bones
9. Survey Finds Increasing Popularity Of Acute Stroke Teams In U.S. Hospitals
10. Strategy effective against drug resistant tuberculosis
11. Study shows patch therapy may be as effective as oral medications

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes , which specializes ... of the facility as part of a disaster drill on October 3rd. , Apple ... Shelton City Emergency Manager, as well as the Connecticut Long Term Care Mutual ...
(Date:10/13/2017)... RIDGE, N.J. (PRWEB) , ... October 13, 2017 , ... ... annual Holly Day Market. Featuring a collection of specialty vendors and unique items from ... of personalized and quality-focused health and wellness services offered by the VNA. The ...
(Date:10/13/2017)... NJ (PRWEB) , ... October 13, 2017 , ... Global ... at scenic Alexandria Park in Milford, NJ. This free event, sponsored by Global ... physical activity. The fun run is geared towards children of all ages; it ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob Lowe, ... in a new episode of "Success Files," which is an award-winning educational program ... investigates each subject in-depth with passion and integrity. , Sciatica occurs when the ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... DIEGO , Oct. 12, 2017   Divoti USA ... Alert Jewelry up to the standard of the latest FDA requirements, ... June 2017). Anyone in need of Medical ID jewelry ... Medical Alert Jewelry are engraved in terms of the ... Divoti ...
(Date:10/11/2017)... Texas , Oct. 11, 2017  True ... services, has amplified its effort during National Breast ... about hereditary cancer risks. ... of Clinical Oncology calculated that more than 10 ... have inherited mutations in BRCA1 or BRCA2 and have ...
(Date:10/7/2017)... --  Provista, a proven leader in the supply ... power, today announced a new resource area on Provistaco.com ... is the online home for case studies, articles on ... releases, slideshows and events. ... at their fingertips, viewers can also watch short videos ...
Breaking Medicine Technology:
Cached News: