HOME >> MEDICINE >> NEWS
Popular anti-epileptic drug also effective in controlling debilitating symptom of multiple sclerosis

A study published in the December issue of Archives of Neurology and currently available online shows that levetiracetam reduced phasic spasticity, which is marked by spasms and painful muscle cramps, in 100 percent of patients in a small clinical study.

"It's amazing how many MS patients can't walk, can't move, and you treat their spasticity and they're fine," said Dr. Kathleen Hawker, assistant professor of neurology at UT Southwestern and lead author of the study. "What's nice about these drugs is that they also work for nerve pain, which in turn improves the patient's mood, so we can use one drug for three things instead of prescribing pain killers and antidepressants in addition to the spasticity therapies."

Spasticity is often seen in patients with MS and amyotrophic lateral sclerosis (ALS), as well as after a stroke or spinal-cord injury. It can lead to loss of balance, increased risk of falls, pain, fatigue, and walking difficulties.

Drugs currently used to treat spasticity may cause memory problems, weakness and lethargy in some patients.

"We're trying to look at medicines that can be used for multiple symptoms so we don't get into a lot of drug interactions," Dr. Hawker said. "If we can get the same results with a better-tolerated drug, that's great for our patients."

Researchers examined the histories of 11 patients treated with levetiracetam between January 2001 and June 2002 for MS-related spasticity at Southwestern Medical Center. The patients were treated with levetiracetam for one to four months, with dosages starting at 250 milligrams per day and increasing to 3,000 mg per day. Researchers found that leviteracetam decreased phasic spasticity in patients taking the drug alone as well as in those who took it in combination with other therapies for spasticity. Tonic spasticity, which produces stiffness, did not improve. Overall, the clinical investigators found the side effects of levetiracetam to be gener
'"/>

Contact: Rachel Horton
rachel.horton@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
15-Dec-2003


Page: 1 2

Related medicine news :

1. Popular chewing gum eliminates bacteria that cause bad breath
2. Popular drug for chest pain may promote blood vessel damage
3. Popular long-acting contraceptive linked to vascular dysfunction
4. Popular asthma drug inadequate when used alone, new study shows
5. Popular herbal remedy fails effectiveness test for tinnitus
6. Popular notions about breast cancer-psychology link challenged
7. Sexually Oriented Internet Sites Are Popular And Non-Problematic For Most People, But Pose Risks For Some
8. UCSF Study Finds Popular Blood Thinner Does Not Weaken Bones
9. Survey Finds Increasing Popularity Of Acute Stroke Teams In U.S. Hospitals
10. Strategy effective against drug resistant tuberculosis
11. Study shows patch therapy may be as effective as oral medications

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/16/2017)... ... ... One thing common to all types of cancer is that it’s a ... money spent screening for and treating cancer in the United States is estimated to ... than in any other country that has an advanced healthcare system, sometimes spending as ...
(Date:1/16/2017)... , ... January 16, 2017 , ... ... been appointed Chief Executive Officer of the medical device company, effective immediately. , ... Robert Storey. “Kevin has a strong track record in medical device market ...
(Date:1/15/2017)... ... ... In this role, Courtney will be responsible for developing new business initiatives ... mark. This certification program was created by ASL and the nonprofit Asthma and Allergy ... for the 60+ million people living in the U.S. with asthma and allergies. Courtney ...
(Date:1/15/2017)... , ... January 15, 2017 , ... Whole Health Supply, LLC is announcing the release ... are also new avenues for purchase. , The 2017 edition has wide jaws that ... for the older boomers as well as diabetics. This handle is reinforced for extra strength ...
(Date:1/15/2017)... Viejo, California (PRWEB) , ... January 15, 2017 , ... ... a stylistic slideshow with complete customization and ease," said Christina Austin - CEO of ... of controls so that users can edit the style and animation of their slideshows. ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... Jan. 17, 2017  Tetra Discovery Partners today ... as Vice President, Clinical Operations. He joins ... Executive Director, Clinical Project Management. "Richard joins ... experience in global clinical research planning and execution, ... clinical operation build-outs and development partnerships," said ...
(Date:1/17/2017)... 17, 2017 - First major agreements signed ... market expected to grow by a CAGR of approximately 6-9% ... holding company which operates globally across a number of sectors, announces ... of notable successes and is well-positioned for further expansion within the ... ...
(Date:1/16/2017)... , Jan. 16, 2017  An aneurysm develops due ... balloon-like dilation. Aneurysms can occur in any artery, ... blood vessel that supplies blood to legs. Most aortic aneurysms ... the abdomen and are referred as abdominal aortic aneurysms, sometimes ... diameter of the aorta in the abdomen is about 2 ...
Breaking Medicine Technology:
Cached News: