HOME >> MEDICINE >> NEWS
Postmenopausal hormone therapy offers no protection against heart attacks

Although therapy with hormones was once thought to protect women's hearts after menopause, a UCSF-led study has found that, at least for women with heart disease, estrogen plus progestin therapy does not reduce the risk of heart attack or death.

The July 3, 2002 issue of the Journal of the American Medical Association (JAMA) contains two articles with the results of the Heart and Estrogen/Progestin Replacement Follow-up Study (HERS II).

HERS was a randomized, blinded trial to determine the effects of estrogen plus progestin (compared with placebo) in older postmenopausal women with heart disease. In 1998 HERS scientists reported that, surprisingly, risk of heart attack increased in the hormone therapy group during the first year of HERS. The risk seemed to decrease in the next several years, leading to the HERS II follow-up study to evaluate the effects of longer-duration hormone therapy.

The trend toward a reduced risk of heart attacks did not persist with additional follow-up. During almost 7 years, combining HERS and HERS II, there was no reduction in risk among women taking hormones.

"This follow-up study found no reduction in risk of heart attacks or death for women with heart disease during up to seven years of hormone therapy. Not only was there no cardiovascular benefit, there were adverse affects, including blood clots and gallbladder disease," said Deborah Grady, MD, MPH, UCSF professor of epidemiology and medicine and co-principal investigator on the studies. Grady is also director of the UCSF/Mount Zion Women's Health Clinical Research Center.

The hormone therapy caused a 2-fold increase in the risk of blood clots in the legs and lungs, with most of the increased risk in the early years of treatment, according to principal investigator Stephen Hulley, MD, MPH, professor and chair of the UCSF department of epidemiology and biostatistics. There was a nearly 50 percent increase in the risk of gallbladder disease r
'"/>

Contact: Maureen McInaney
mmcinaney@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
2-Jul-2002


Page: 1 2

Related medicine news :

1. Postmenopausal breast cancer survivors at increased risk for bone fractures
2. Postmenopausal women have lower grip strength than premenopausal women
3. Postmenopausal hormone therapy associated with increased risk for developing asthma
4. Postmenopausal hormone replacement therapy linked to increased risk for certain types of rarely occurring breast cancer
5. Postmenopausal Women Reap Heart Benefits From Foods Containing Vitamin E
6. Novel Therapy Significantly Reduces Spinal Fractures In Postmenopausal WomenWith Two Years Of Therapy
7. New Drug Prevents Breast Cancer In Postmenopausal Women, UCSF Researchers Report
8. Growth hormone treatment improves symptoms of metabolic disorder in postmenopausal women
9. Mood elevating hormone may trigger depression and heart problems
10. The history and controversy behind post-menopausal hormone therapy
11. Female sex hormones play a vital role in defense against sexually transmitted diseases

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... ... February 24, 2017 , ... In the Health Care IT campaign, ... priority because it’s not if you will be attacked, but when.” However, he and ... to digital health care. , Improvements in auditing and monitoring have taken security in ...
(Date:2/24/2017)... ... ... Healthcare Associates of McKinney announced today that they have moved one ... 121, Suite 210, McKinney, Texas 75070. It is in the heart of the ... has grown, the need for more space has been paramount. This beautiful new ...
(Date:2/24/2017)... ... February 24, 2017 , ... With ProGlass Prism users now have ... Users have total control over position, rotation, distortion, edge softness, edge blur, chromatic aberration, ... Pro X. , With ProGlass Prism users are given the tools and effects ...
(Date:2/24/2017)... ... ... Yisrayl Hawkins, Pastor and Overseer at The House of Yahweh, has published a ... an astounding statement when he says that the entire Bible was written for the ... times so plainly that anyone should be able to see the time period. He ...
(Date:2/24/2017)... ... February 24, 2017 , ... Indiana Fiber Network (IFN) President and CEO Kelly ... Dyer started as the Chairman of the Management Committee when IFN was originally ... including the recruitment of investor/owners and development of the business plan. He became ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... Following receiving CE Marking in Europe ... AMAR is a major milestone for the country where the device was developed ... market in Israel   ... inclusion in the National Health Basket , Israel , ... E-QURE Corp. (OTCQB: EQUR), a leader in medical devices for the treatment of advanced wound ...
(Date:2/24/2017)... Research and Markets has announced the addition of the ... report to their offering. ... The Global Empty Capsules Market is poised to grow at a ... billion by 2025. This industry report analyzes the market ... as regional levels presented in the research scope. The study provides historical ...
(Date:2/24/2017)... , Feb. 24, 2017 Physician General ... Drug and Alcohol Programs Jennifer Smith commended ... providing training for and using naloxone, a life-saving overdose ... McCullough , a recovery specialist and overdose survivor who ... EMS providers. "A significant part of fighting ...
Breaking Medicine Technology:
Cached News: