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Potential drug target for treating cocaine abuse found

cal structure of those substances," says NIDA's Amy Newman, who synthesized the compound. The researchers found that their novel drug made contact with transporters slowly about 10 times slower than cocaine which, they speculate, may be why it does not have a stimulating effect.

Between 2 million and 3.2 million people in the United States about 1 percent of the population - use cocaine, according to estimates. Of this number, more than 550,000 are crack users. In 2002, 1.5 million Americans were thought to be dependent on or abusing cocaine. "Cocaine is capable of destroying not only the lives of those addicted, but also the lives of those around them," says Katz. "An effective treatment for cocaine addiction would be of immeasurable help to these individuals and their families."


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Contact: Elissa Petruzzi
elissa@sfn.org
202-462-6688
Society for Neuroscience
22-Feb-2005


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