HOME >> MEDICINE >> NEWS
Premature infants with lung disease may continue to need replacement substance to ease breathing

Physicians have known for decades that many premature babies suffer respiratory problems stemming from insufficiency of a lung substance called surfactant during their first few weeks of life. The standard treatment has been to provide replacement surfactant immediately after birth. A new study has found that even after infants begin producing their own surfactant, it often fails to function properly in premature infants who continue to have lung disease after their first week.

The study also raises the question of whether additional replacement surfactant treatment may benefit such infants, just as it does in the week after birth.

Neonatology researchers from The Children's Hospital of Philadelphia and the University of Pennsylvania published the study in the October 20 online edition of the journal Pediatric Research. It was the first study of surfactant dysfunction in infants beyond the first week of life.

"We studied premature babies who require mechanical ventilation to breathe after one week of age," said Philip L. Ballard, M.D., Ph.D., director of Neonatology Research at The Children's Hospital of Philadelphia. "We found that three-quarters of these high-risk infants have episodes of surfactant dysfunction, and these episodes are associated with worsening of their respiratory status."

Surfactant is a naturally produced mixture of proteins and lipids (fats) that lowers surface tension within alveoli, the tiny air sacs within the lungs. By doing so, it prevents the alveoli from collapsing during exhalation, and eases the work of breathing. Premature infants have underdeveloped respiratory systems and do not produce enough of their own surfactant. Therefore, physicians have found that supplying replacement surfactant may improve infants' lung function during the earliest period after birth.

Replacement surfactant is discontinued after babies begin to produce enough surfactant on their own. However, infants wi
'"/>

Contact: John Ascenzi
ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
15-Nov-2004


Page: 1 2

Related medicine news :

1. UCSF Study Finds Latina Women Have Greater Risk Of Premature Birth With Short Interpregnancy Interval
2. Intensive Program Can Help Premature Babies Learn At the Start
3. University Of North Carolina-Chapel Hill (UNC-CH) Study: Parents Wishes, Uncertainty Determine Resuscitation Of Premature Infants
4. Study Questions Common Practice Of Steroid Administration To Induce Lung Development In Premature Infants
5. NIAID Stops AIDS Study Prematurely Because Drug Cocktail Boosts Survival
6. Premature Birth Sometimes Can Adversely Affect Infants Ties To Mother
7. UMaine study looks at infants and chronic nighttime crying
8. Hospital acquired infections present major problem for infants in developing countries
9. Cigarette smoke worsens respiratory infections in infants
10. Columbia researchers receive $3 million to combat genetic killer of infants & toddlers
11. Brain tumor with dismal prognosis in infants can be cured in older children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2019)... , ... December 06, 2019 , ... ... recognized for its innovations and excellence in patient care. On December 12th, Hartford ... of excellence at the Health Care Heroes Awards at the Hartford Marriott. , ...
(Date:12/6/2019)... , ... December 06, 2019 , ... Allegheny Health Network ... Dr. Gyure, who joined AHN from WVU Medicine in May 2018, previously served as ... has served as interim chair since October and is also part of the pathology ...
(Date:12/6/2019)... ... December 06, 2019 , ... COMPLIANCY GROUP is proud ... Wyoming Medical Society. Compliancy Group is dedicated to educating and assisting Wyoming Medical ... adhere to the standards set forth by the Health Insurance Portability and Accountability ...
(Date:12/6/2019)... ... ... TIME For Kids (TFK) revealed the first-ever list of the World’s ... that are tailored to the interests of kids. The list identifies The Children’s Museum ... TIME for Kids gathered nominations from its network of TFK Kid Reporters ...
(Date:12/5/2019)... ... December 05, 2019 , ... A cohort ... (HRUS) technology to help their patients more easily detect ruptured silicone gel implants. ... this study and reporting on his experience. While the FDA currently recommends regular ...
Breaking Medicine News(10 mins):
(Date:12/9/2019)... , ... December 09, 2019 , ... ... most people contend with are not ‘sebaceous,’” notes Dr. Robert Levine, a dual-board-certified ... epidermoid – also called ‘epidermal’ – cysts, which have their own distinct structure.” ...
(Date:12/8/2019)... (PRWEB) , ... December 07, 2019 , ... ... years to have over 700 weekly ongoing face-to-face mutual support groups in 32 ... nicotine addiction. , Nicotine Anonymous members also provide several daily phone and internet ...
(Date:12/6/2019)... ... December 06, 2019 , ... In order to help pharmacies ... introducing the CSEDOIC luminaire series. CSEDOIC fixtures are designed for healthcare cleanrooms, where ... hazardous drugs (HDs) and HD-active pharmaceutical ingredients from the original container be done ...
Breaking Medicine Technology:
Cached News: