HOME >> MEDICINE >> NEWS
Promise of 'bladder pacemaker' for people with spinal cord injury

heir bladders through coordinated bladder and urethral sphincter activity. NIH animal care and experimental procedures were followed and approved by the Institutional Animal Care and Use Committee of Case Western Reserve University, where the studies took place.

Until now, most bladder control research has focused on treating incontinence, a major cause of health problems such as urinary tract and kidney infections, and of skin degradation. Other research teams have reported that electrical pulses with low frequencies, about 2 to 20 cycles per second, help control incontinence by calming involuntary bladder contractions, while higher-frequency pulses do not help.

The new research demonstrates that the higher-frequency pulses fail to control incontinence because they trigger bladder contractions. The team found that frequencies in the range of 20 to 40 cycles per second work best for bladder emptying.

"It was a surprise that no one had figured this out yet. But now that we understand the whole picture, we can pursue an engineered solution to help people restore bladder control," Boggs said.

"With this new understanding of the function of the pudendal nerve and the beneficial application of both high- and low-frequency pulses in controlling bladder emptying and incontinence, it should be possible for us to create a 'bladder pacemaker' analogous to a heart pacemaker," said Grill, who previously (in 2004) published preliminary human research that supports his optimism in extrapolating from the new studies with cats. Those earlier studies showed that a similar reflex in bladder contraction exists in people with SCI.

In January 2005, the National Institutes of Health awarded Grill a 5-year, $1.8 million grant to develop a system to sense involuntary bladder contractions and trigger a calming low-frequency electrical signal. The project also seeks to enable patients to generate a high-frequency signal on demand so they can emp
'"/>

Contact: Deborah Hill
dahill@duke.edu
919-660-8403
Duke University
1-Feb-2005


Page: 1 2 3

Related medicine news :

1. Promise for helping adults with dyslexia
2. Promise of stem cells amplified
3. Promise of laparoscopic liver resection for liver cancer explored in unique program
4. Anti-Depressant Drug Shows Promise As Weight-Loss Treatment
5. Sniffing Out The Promise Of Anti-Angiogenesis Therapy
6. Treatment-Resistant Depression: Results of Latest Electromagnetic Stimulation Study Show Promise
7. Alga-Based Compound Promises Less Bleeding On The Battlefield
8. Therapy Developed At Cedars-Sinai Medical Center Shows Promise In Preventing Rejection Of Transplanted Organs
9. New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease
10. "Plugs" For Drugs Promise Mightier Medicines
11. DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2017)... ... ... “When the Stars Lead Home”: a poignant story of loss, determination, and perseverance. ... an avid reader who lives in the Pacific Northwest with her husband, daughter, two ... Camp. She couldn’t be more grateful. , Twelve-year old Tizzy could not believe how ...
(Date:5/26/2017)... ... May 26, 2017 , ... Water damage to the flooring of ... District had left education officials with a number of critical issues to address before ... had to be accomplished with little or no disruption to class schedules. Second, the ...
(Date:5/24/2017)... ... May 24, 2017 , ... ... image management and interpretation, has received U.S. Food and Drug Administration (FDA) ... a web-based, scalable and secure cloud platform for medical image management. At the ...
(Date:5/24/2017)... ... 2017 , ... Myers Jackson is well known for auctioning homes that people ... anywhere on the planet. The luxury home market is alive and well and there ... quick search of “11 Spyglass Hill Auction will enlighten you on the dynamics of ...
(Date:5/24/2017)... ... 2017 , ... If you are thinking of a visit to San Francisco , fall ... the perfect time to visit. , Business Architecture Associates is pleased to offer 5 days ... as a 4-½ day package for individuals, and as 4-½ day corporate package for up ...
Breaking Medicine News(10 mins):
(Date:5/22/2017)... May 22, 2017  As the specialty pharmacy ... continue to make the revolutionary shift from volume-based ... for ensuring positive patient outcomes and shaping the ... shifting focus away from clinical trials and toward ... long-term specialty drug therapy utilization in precise patient ...
(Date:5/15/2017)... Enterin Inc., a privately-held CNS pharmaceutical company based ... to treat Parkinson,s disease (PD), has enrolled the first patient ... randomized, controlled, multicenter study involving patients with PD and taking ... over a 9-to-12-month period. The first stage is open label ... Participating sites include Denver , ...
(Date:5/10/2017)... , May 10, 2017 Global Health ... Latin America , published its 2017 ranking ... ranking is based on extensive data analysis from GHI,s ... largest hospitals database for the region. The GHI database covers ... , offering more than 130 data points for each institution ...
Breaking Medicine Technology:
Cached News: