HOME >> MEDICINE >> NEWS
Promise of 'bladder pacemaker' for people with spinal cord injury

heir bladders through coordinated bladder and urethral sphincter activity. NIH animal care and experimental procedures were followed and approved by the Institutional Animal Care and Use Committee of Case Western Reserve University, where the studies took place.

Until now, most bladder control research has focused on treating incontinence, a major cause of health problems such as urinary tract and kidney infections, and of skin degradation. Other research teams have reported that electrical pulses with low frequencies, about 2 to 20 cycles per second, help control incontinence by calming involuntary bladder contractions, while higher-frequency pulses do not help.

The new research demonstrates that the higher-frequency pulses fail to control incontinence because they trigger bladder contractions. The team found that frequencies in the range of 20 to 40 cycles per second work best for bladder emptying.

"It was a surprise that no one had figured this out yet. But now that we understand the whole picture, we can pursue an engineered solution to help people restore bladder control," Boggs said.

"With this new understanding of the function of the pudendal nerve and the beneficial application of both high- and low-frequency pulses in controlling bladder emptying and incontinence, it should be possible for us to create a 'bladder pacemaker' analogous to a heart pacemaker," said Grill, who previously (in 2004) published preliminary human research that supports his optimism in extrapolating from the new studies with cats. Those earlier studies showed that a similar reflex in bladder contraction exists in people with SCI.

In January 2005, the National Institutes of Health awarded Grill a 5-year, $1.8 million grant to develop a system to sense involuntary bladder contractions and trigger a calming low-frequency electrical signal. The project also seeks to enable patients to generate a high-frequency signal on demand so they can emp
'"/>

Contact: Deborah Hill
dahill@duke.edu
919-660-8403
Duke University
1-Feb-2005


Page: 1 2 3

Related medicine news :

1. Promise for helping adults with dyslexia
2. Promise of stem cells amplified
3. Promise of laparoscopic liver resection for liver cancer explored in unique program
4. Anti-Depressant Drug Shows Promise As Weight-Loss Treatment
5. Sniffing Out The Promise Of Anti-Angiogenesis Therapy
6. Treatment-Resistant Depression: Results of Latest Electromagnetic Stimulation Study Show Promise
7. Alga-Based Compound Promises Less Bleeding On The Battlefield
8. Therapy Developed At Cedars-Sinai Medical Center Shows Promise In Preventing Rejection Of Transplanted Organs
9. New Type Of Artificial Surfactant Shows Promise In Treating Lung Disease
10. "Plugs" For Drugs Promise Mightier Medicines
11. DNA-Based Cancer Vaccine Shows Promise To Successfully Treat Melanoma In Mice

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... established the certification process to promote standards of excellence for the field of ... scheduled for March 22 – 25, 2018 in Orlando, Florida at the Omni ...
(Date:10/13/2017)... ... 2017 , ... Lori R. Somekh, founder of the Law Office of ... elder law and special needs planning attorneys. “Membership in ElderCounsel helps our office remain ... to network with elder law attorneys nationwide,” said Somekh. , ElderCounsel ...
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of ... collection of specialty vendors and unique items from across the nation, this holiday-themed event ... wellness services offered by the VNA. The boutique will be open Saturday, November ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... most popular and least understood books in the Holy Scriptures, Revelation. The Book of ... baffled scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical ... innovative solutions for injectable drug administration, today shared the ... ID Adapter for improving the intradermal administration of polio ... Skin Vaccination Summit in May 2017 by Dr. ... Polio Department, World Health Organization (WHO), and recently published ...
(Date:10/4/2017)... 4, 2017 OBP Medical , ... medical devices, today announced regulatory approval from ... (or Agência Nacional de Vigilância Sanitária (ANVISA)) to ... surgical retractor with integrated LED light source and ... and exposure of a tissue pocket or cavity ...
(Date:10/2/2017)... Denmark , Oct. 2, 2017 The Rebound ... in the struggle to reverse the tide of prescription drug ... for regulating their medicine intake and stepping down their dosage ... set to launch in December 2017; the first 100,000 people ... Learn more at http://www.rebound-solution.com/ ...
Breaking Medicine Technology:
Cached News: