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Prostate cancer hormonal therapy may increase sexual and physical problems

with ADT reported a reduction in physical comfort and vitality one year after therapy. However, 58% of men receiving ADT, compared with 46% of men receiving no therapy, believed they were free of cancer.

The authors conclude that, ADT is a commonly used primary therapy for localized prostate cancer. Therefore, men considering ADT as an initial treatment should be aware that sexual function and some aspects of physical well-being are likely to be affected in the first year following this treatment.

In a related editorial, James A. Talcott, M.D., of the Massachusetts General Hospital, points out that roughly two-thirds of urologists recommend ADT for early prostate cancer even though the evidence backing the effectiveness of ADT has been lacking.

Patients deserve better information from randomized clinical trials to help them make [treatment] decisions, he concludes. Leaving them to ill-informed hunches is chancy medicine and the road to poor, expensive health policy.


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Contact: Linda Wang
jncinews@oup-usa.org
301-841-1287
Journal of the National Cancer Institute
19-Mar-2002


Page: 1 2

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