HOME >> MEDICINE >> NEWS
Prototype developed for ultrasonic patch to deliver insulin

Penn State engineers have developed a prototype for an ultrasound insulin delivery system that is about the size and weight of a matchbook that can be worn as a patch on the body.

Dr. Nadine Barrie Smith, assistant professor of bioengineering, says, "The new Penn State ultrasound patch, which operates in the same frequency range as the large commercially available sonic drug delivery devices, is about an inch-and-a-half by an inch-and-a-half in size and weighs less than an ounce. Commercially available sonicators currently have a probe about eight inches long which weighs over two pounds."

Experiments with human skin and with live rats have shown that the new ultrasound patch delivers therapeutically effective doses of insulin.

The new prototype is described in detail in "Transducer Design for a Portable Ultrasound Enhanced Transdermal Drug-Delivery System," published in the current (October) issue of the IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

The key to the new ultrasound patch is a "cymbal" transducer developed by Dr. Robert Newnham, the Alcoa professor emeritus of solid state science. The transducer produces the sound waves that drive the medication through the skin and into the blood stream. The cymbal transducer consists of a thin disk of piezoelectric ceramic material sandwiched between titanium end caps shaped like cymbals. Four of these transducers are used in the prototype.

A thin reservoir of insulin is placed in front of the cymbal transducer and when a current is applied, sound waves just above the level of human hearing push the medication through the skin and into the blood vessels.

Smith notes, "Our experiments with rats show that an exposure of 20 minutes produced the same result as a 60-minute exposure. So, we are hopeful that, eventually, we may be able to tune the system so that one to five minutes of exposure may be enough."

Currently, diabeti
'"/>

Contact: Barbara Hale
bah@psu.edu
814-865-9481
Penn State
22-Oct-2002


Page: 1 2

Related medicine news :

1. Prototype system developed by Wright State computer engineer allows blind to see
2. Computer model being developed at Stanford may help surgeons better predict patient outcomes
3. Case definition for polyneuropathy developed to standardize research
4. New marrow transplant method developed at Stanford may eliminate fatal side effects
5. Rutgers-developed biomaterial drives a technology transfer story toward success
6. Method developed to replicate stem cells from the heart
7. Patients with severe depression improve using guidelines developed by UT Southwestern researchers
8. Sandia-developed foam likely would stop SARS virus quickly, Sandia/Kansas State team shows
9. New dressing for wounds developed at Hebrew University
10. Successful, rapid protein crystallization possible with technique developed by UCSD researcher
11. Urban areas organized in well developed partnering markets

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2019)... ... February 19, 2019 , ... ... stigma in pregnant and postpartum women, a team led by a Worcester Polytechnic ... postpartum often show increased depressive symptoms, greater weight gain during pregnancy, and weight ...
(Date:2/19/2019)... ... February 19, 2019 , ... Landscape Structures Inc., a Delano, Minn.-based commercial ... to be a stunning and fun addition to any play space. Spinning is one ... Curva™ Spinners will provide kids’ brains with valuable equilibrium information. , Whether park and ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... experience to The Oncology Institute of Hope and Innovation. , Dr. Lombardi completed ... cum laude. He received his medical degree from the University of Rochester School ...
(Date:2/19/2019)... ... February 19, 2019 , ... ClearHealth ... to Foley & Lardner LLP, as Recognized Consultants. The CHQI Recognized Consultant Program ... in pursuing CHQI accreditation. , Ms. Wein and Mr. Einhorn are part ...
(Date:2/19/2019)... Fla. (PRWEB) , ... February 18, 2019 , ... ... in the nation to test the PathO3Gen Solutions Footwear Sanitizing Stations to maximize ... Solestice 3/15 TechnologyTM to kill superbugs such as MRSA and C. difficile, which ...
Breaking Medicine News(10 mins):
(Date:2/19/2019)... (PRWEB) , ... February 19, ... ... and infrastructure solutions provider for global service providers, enterprises, and developers, announced ... orchestration platform with the Arvizio MR Studio mixed reality visualization and collaboration ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... for Stage IV metastatic breast cancer (MBC), announces the opening of the 2019 ... Fairchild, “In honor of our 10-year anniversary, we are excited to announce we ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... completed his new book “Live Hard Die Young.” Dr. Oexner was the first ... medicine, therapeutic exercise physiology, and nutritional counseling. Dr. Oexner was a supervisor on ...
Breaking Medicine Technology:
Cached News: