HOME >> MEDICINE >> NEWS
'Reduced exposure' tobacco products lessen carcinogen exposure, but medicinal nicotine better

Smokers and other tobacco users who switch to "reduced exposure" tobacco products lessen their exposure to tobacco-associated carcinogens, and those who switch to medicinal nicotine get an even greater reduction, according to a new study that appears in the June 2 issue of the Journal of the National Cancer Institute.

Tobacco users who cannot or will not quit but would like to limit their exposure to carcinogens may instead switch to tobacco products advertised as having less of these harmful chemicals. Although some tobacco companies have developed methods to reduce the formation of nitrosamines--the most abundant and potent tobacco carcinogens, which are created during the curing, fermentation, and aging of tobacco leaves--it is not known if, compared to medicinal nicotine, these products are safer or how much they reduce carcinogen exposure in people.

To evaluate the effects of switching to these products, Dorothy K. Hatsukami, Ph.D., of the University of Minnesota Transdisciplinary Tobacco Use Research Center in Minneapolis, and colleagues measured carcinogen uptake in 54 users of smokeless tobacco and 51 cigarette smokers who switched to either a "reduced exposure" tobacco product (Swedish snus for the smokeless tobacco users and OMNI cigarettes for the smokers) or medicinal nicotine (nicotine patch). The researchers measured levels of tobacco-specific nitrosamines in the urine of all participants weekly for 2 weeks before and 4 weeks after the switch. Smokers were also assessed for levels of a biomarker for polycyclic aromatic hydrocarbon uptake.

Each of the four groups of subjects had reduced levels of nitrosamines during the 4 weeks after the switch, although subjects in the medicinal nicotine groups had greater reductions. In addition, among the cigarette smokers, only those who switched to medicinal nicotine experienced a reduction in levels of the biomarker for polycyclic aromatic hydrocarbon uptake. The researchers also note that
'"/>

Contact: Sarah L. Zielinski
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
1-Jun-2004


Page: 1 2

Related medicine news :

1. Short-term effects of spit tobacco suggest long-term health risks
2. Teen athletes continue tobacco use, despite severe consequences
3. Study examines racial differences among children to environmental tobacco smoke exposure
4. How links with tobacco industry may have influenced the publication of research on second-hand smoke
5. NIH awards USC $8.7 million to study tobacco use in China
6. Alcohol: Global burden on health similar to tobacco and high blood pressure
7. Marijuana associated with same respiratory symptoms as tobacco
8. Environmental tobacco smoke linked to reading, math, logic and reasoning declines in children
9. Leading tobacco manufacturer conceals links to tobacco research facility
10. European nations urged to ratify international treaty on tobacco control
11. Nicotine more addictive when combined with other tobacco smoke chemicals, UCI study finds

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/28/2016)... , ... May 28, 2016 , ... After a year and a half of planning ... an extraordinary event. The Multiple Pathways of Recovery Conference was held May 2 -4, ... country and the United Kingdom came together to explore the many pathways individuals use to ...
(Date:5/27/2016)... ... May 27, 2016 , ... W.S. Badger Co. Inc ... that it has been recognized as one of the best small businesses for new ... as one of nine small businesses providing progressive benefits to new parents on the ...
(Date:5/27/2016)... ... May 27, 2016 , ... In response ... many who are unaware of the plight of aphasia. In collaboration with the ... “Stroke Awareness” campaign. , The link between stroke and aphasia is relatively unknown, ...
(Date:5/27/2016)... ... May 27, 2016 , ... With a team of ... food industries. Aside from its GMP accreditation, Validation Center is also a registered ... products, services and staff. , Validation Center is ISO17025 accredited and only offers ...
(Date:5/26/2016)... ... 26, 2016 , ... Intalere, the healthcare industry leader in ... inaugural Member Conference at the Paris Hotel in Las Vegas, Nev., May 17-20, ... America’s healthcare providers. , The conference was highlighted by the announcement of the ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... Amarantus BioScience Holdings, Inc. ... Regenerative Medicine, Neurology and Orphan Diseases, today announced that President & ... upcoming investor conferences: SeeThru Equity MicroCap Conference   ... New York City , NY When: Tuesday, May ... Conference   Where: Grand Hyatt Hotel, 109 East 42 ...
(Date:5/26/2016)... NASHVILLE, Tenn. , May 26, 2016 ... provider of software and analytics, network solutions ... healthcare, today announced it entered into a ... leading provider of outpatient software solutions and ... surgery centers, specialty hospitals and rehabilitation clinics ...
(Date:5/25/2016)... , Germany and GERMANTOWN, ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... licensing and co-development agreement with Therawis Diagnostics GmbH to develop ... be to develop and market PITX2 as a marker to ... high-risk breast cancer patients. "We are pleased to ...
Breaking Medicine Technology:
Cached News: