HOME >> MEDICINE >> NEWS
'Reduced exposure' tobacco products lessen carcinogen exposure, but medicinal nicotine better

Smokers and other tobacco users who switch to "reduced exposure" tobacco products lessen their exposure to tobacco-associated carcinogens, and those who switch to medicinal nicotine get an even greater reduction, according to a new study that appears in the June 2 issue of the Journal of the National Cancer Institute.

Tobacco users who cannot or will not quit but would like to limit their exposure to carcinogens may instead switch to tobacco products advertised as having less of these harmful chemicals. Although some tobacco companies have developed methods to reduce the formation of nitrosamines--the most abundant and potent tobacco carcinogens, which are created during the curing, fermentation, and aging of tobacco leaves--it is not known if, compared to medicinal nicotine, these products are safer or how much they reduce carcinogen exposure in people.

To evaluate the effects of switching to these products, Dorothy K. Hatsukami, Ph.D., of the University of Minnesota Transdisciplinary Tobacco Use Research Center in Minneapolis, and colleagues measured carcinogen uptake in 54 users of smokeless tobacco and 51 cigarette smokers who switched to either a "reduced exposure" tobacco product (Swedish snus for the smokeless tobacco users and OMNI cigarettes for the smokers) or medicinal nicotine (nicotine patch). The researchers measured levels of tobacco-specific nitrosamines in the urine of all participants weekly for 2 weeks before and 4 weeks after the switch. Smokers were also assessed for levels of a biomarker for polycyclic aromatic hydrocarbon uptake.

Each of the four groups of subjects had reduced levels of nitrosamines during the 4 weeks after the switch, although subjects in the medicinal nicotine groups had greater reductions. In addition, among the cigarette smokers, only those who switched to medicinal nicotine experienced a reduction in levels of the biomarker for polycyclic aromatic hydrocarbon uptake. The researchers also note that
'"/>

Contact: Sarah L. Zielinski
jncimedia@oupjournals.org
301-841-1287
Journal of the National Cancer Institute
1-Jun-2004


Page: 1 2

Related medicine news :

1. Short-term effects of spit tobacco suggest long-term health risks
2. Teen athletes continue tobacco use, despite severe consequences
3. Study examines racial differences among children to environmental tobacco smoke exposure
4. How links with tobacco industry may have influenced the publication of research on second-hand smoke
5. NIH awards USC $8.7 million to study tobacco use in China
6. Alcohol: Global burden on health similar to tobacco and high blood pressure
7. Marijuana associated with same respiratory symptoms as tobacco
8. Environmental tobacco smoke linked to reading, math, logic and reasoning declines in children
9. Leading tobacco manufacturer conceals links to tobacco research facility
10. European nations urged to ratify international treaty on tobacco control
11. Nicotine more addictive when combined with other tobacco smoke chemicals, UCI study finds

Post Your Comments:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
(Date:12/15/2014)... , Dec. 15, 2014  Colorado and ... have legalized adult use of cannabis. Oregon ... D.C. ended prohibition during the November 2014 elections. ... Photo - http://photos.prnewswire.com/prnh/20141212/164153LOGO The benefits ... noted and obvious benefits like the increased tax revenue for ...
(Date:12/15/2014)... -- The Government of Ghana has endorsed a ... and Terumo BCT to respond to the emerging Ebola crisis within ... health system capacity to the citizens of Ghana ... Readiness and Resilience Initiative (GERRI) is a multi-agency effort designed to: ... possible arrival of the Ebola epidemic , Provide new blood ...
(Date:12/13/2014)... -- Radiologists can transmit their reports, which can also ... electronic health records (EHR) systems securely, efficiently, and ... That was the message behind a presentation ... recent Radiology Society of North America Meeting (RSNA) ... this manner also helps referring physicians satisfy one ...
Breaking Medicine Technology:CannaInsider.com Estimates 200,000 New Jobs in the Cannabis Industry by 2015 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 3Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 4Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 5Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 6Advanced Data Systems Presents on Interface-Free EHR Communications at RSNA's 2014 Conference: Streamlining Communication of Reports and Images to Referring Physicians 2Advanced Data Systems Presents on Interface-Free EHR Communications at RSNA's 2014 Conference: Streamlining Communication of Reports and Images to Referring Physicians 3
Cached News: