HOME >> MEDICINE >> NEWS
Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein

CHAPEL HILL Aggressive therapy with statins -- drugs that inhibit cholesterol synthesis -- works better than moderate statin therapy in reducing fats and proteins in the blood that have been linked to atherosclerosis, a new multi-center study concludes. Statins' effects on both complex compounds appear beneficial in cutting patients' cardiovascular risks.

Atherosclerosis is the progressive disease process, often called hardening of the arteries, in which blood vessels slowly narrow with brain- and heart-threatening plaque, something like rust blocking water flow in an iron pipe.

A report on the research appears in Thursday's (Jan. 6) issue of the New England Journal of Medicine.

More than three dozen investigators from across the country participated in the research, including first author Dr. Steven E. Nissen of the Cleveland Clinic Foundation and Dr. Sidney C. Smith Jr.

A past president of the American Heart Association, Smith is professor of medicine and director of the Center for Cardiovascular Science and Medicine at the University of North Carolina at Chapel Hill School of Medicine. He also served on the steering committee of a second, closely related investigation appearing in the same issue and led by Dr. Paul M. Ridker of Harvard Medical School and others.

Scientists designed the first study to investigate the relative contributions of statins in lowering fats in blood and also C-reactive protein (CRP), the most reliable laboratory measure of systemic inflammation in the body. It involved performing ultrasound tests on 502 U.S. patients with documented coronary artery disease.

Half the patients then received 40 milligrams of pravastatin, while the rest underwent the more aggressive treatment of 80 milligrams of atorvastatin. Doctors repeated the ultrasound evaluations 18 months later.

In the group as a whole, the mean LDL cholesterol level dropped from 150.2 milligrams per deci
'"/>

Contact: David Williamson
919-962-8596
University of North Carolina at Chapel Hill
5-Jan-2005


Page: 1 2 3

Related medicine news :

1. Reduced risk of institutionalisation in patients with dementia
2. Reduced exposure tobacco products lessen carcinogen exposure, but medicinal nicotine better
3. Reduced scarring helps nerves grow through spinal injuries
4. Reduced risk for developing type 2 diabetes recommended for inclusion in Xenicals European label
5. Reduced breastfeeding in western countries makes major contribution to incidence of breast cancer
6. WIC, Medicaid Have Reduced Infant Deaths
7. Cervical Screening Has Reduced Incidence And Mortality From Cervical Cancer
8. Reduced Heart Disease Risk In Middle Age Lowers Eventual Medicare Costs
9. Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack Risk Reduced By 47% With Use Of Tirofiban
10. New study in NEJM suggests levodopa may slow progression of Parkinsons disease
11. The impact of body weight on the progression of knee osteoarthritis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/1/2020)... ... April 01, 2020 , ... American hospital workers are ... Coronavirus-infected patients. , Staffers are in particular need of face shields, which protect ... The Wall Street Journal reported that New York City mayor Bill de Blasio's ...
(Date:3/30/2020)... DIEGO (PRWEB) , ... March 30, 2020 , ... ... to new and prospective patients, continuing its commitment to provide comprehensive and compassionate ... , Patients can use Achieve Medical Center’s UpDox platform for telemedicine services including ...
(Date:3/28/2020)... ... March 27, 2020 , ... ... the public from the spread of the coronavirus. Operating under the designation as ... forward with infrastructure renewal and environmental protection projects in the downstate New York ...
(Date:3/28/2020)... ... March 28, 2020 , ... ... Therapy Services (EPPTS), a physical therapist-owned rehabilitation company since 1985 specializing in the ... TX. , “Since we started more than 30 years ago, we have been ...
(Date:3/27/2020)... VEGAS (PRWEB) , ... March 27, 2020 , ... During a time of global distress ... merchant processing, is donating to the UNITE HERE Education and Support Fund in ... pandemic. , UNITE HERE represents 300,000 working people in the food ...
Breaking Medicine News(10 mins):
(Date:4/2/2020)... ... 02, 2020 , ... On April 15, the Center for ... annual Medical Hero Appreci-a-thon to bring the global clinical research community together to ... and study volunteers. CISCRP invites the public to participate in this free ...
(Date:4/1/2020)... ... April 01, 2020 , ... In ... face shields. As large manufacturers nation-wide scramble to retool their machinery to build ... or in extreme cases, using hand-sewn masks to protect employees from contracting infectious ...
(Date:3/30/2020)... ... 30, 2020 , ... “In the time of remote work ... stories from our customers of vendor price-gouging. We are here to promise that ... in this difficult time,” says Borya Shakhnovich, CEO of airSlate -- parent company ...
Breaking Medicine Technology:
Cached News: