HOME >> MEDICINE >> NEWS
Reduced risk for developing type 2 diabetes recommended for inclusion in Xenical's European label

Roche announced today that the European Union's Committee for Proprietary Medicinal Products (CPMP) has given a positive recommendation to extend the European label for its weight loss medication Xenical to include:

  • four year data on weight loss;
  • long-term safety and tolerability profile; and
  • reduced risk for developing type 2 diabetes.

    The decision is based on the results of the landmark XENDOS (XENical in the prevention of Diabetes in Obese Subjects) study, which showed for the first time that a weight loss medication could significantly reduce the risk of developing type 2 diabetes.

    XENDOS is the largest and longest study of a weight loss medication, treating 3304 patients for four years with Xenical plus lifestyle changes, or lifestyle changes alone. It is also the first study to assess whether treatment with a weight loss medication, Xenical, can reduce the risk of developing type 2 diabetes. The study showed that losing weight with Xenical reduced the risk of developing diabetes by 37% compared with lifestyle changes alone and by 52% in patients with impaired glucose tolerance (IGT or pre-diabetes). Compared to lifestyle changes alone, Xenical treatment produced significantly greater long-term weight loss and improvements in cardiovascular risk factors (including blood pressure and lipids). The study also confirmed that Xenical has a long-term safety profile that is unmatched in the field of weight loss.

    "The CPMP's decision is an important step towards expanding the European label for Xenical, which we believe will provide physicians with an effective strategy for helping patients lose weight and thereby delaying or preventing type 2 diabetes," commented Dr. Paul Brown, Life Cycle Leader for Xenical.

    The CPMP's positive opinion will now be proposed for approval by the European Commission.

    Type 2 diabetes

    Health experts have warned of a global epidemic of diabetes caused by a
    '"/>



  • Contact: Liz Gofton
    liz.gofton@shirehealthinternational.com
    44-207-471-1518
    Shire Health International
    30-Jan-2004


    Page: 1 2

    Related medicine news :

    1. Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein
    2. Reduced risk of institutionalisation in patients with dementia
    3. Reduced exposure tobacco products lessen carcinogen exposure, but medicinal nicotine better
    4. Reduced scarring helps nerves grow through spinal injuries
    5. Reduced breastfeeding in western countries makes major contribution to incidence of breast cancer
    6. WIC, Medicaid Have Reduced Infant Deaths
    7. Cervical Screening Has Reduced Incidence And Mortality From Cervical Cancer
    8. Reduced Heart Disease Risk In Middle Age Lowers Eventual Medicare Costs
    9. Study Leads To New Standard Of Care For Treating Unstable Angina: Heart-Attack Risk Reduced By 47% With Use Of Tirofiban
    10. Hospital acquired infections present major problem for infants in developing countries
    11. Helping answer needs by developing specialists in autism

    Post Your Comments:
    *Name:
    *Comment:
    *Email:


    (Date:8/16/2017)... ... ... Blue Health Intelligence (BHI) announced today that Dr. Alan Spiro joined ... 30 years of clinical, healthcare IT, value-based care, and change management experience to BHI ... am thrilled to welcome Dr. Spiro to BHI,” said Swati Abbott, CEO of Blue ...
    (Date:8/16/2017)... California (PRWEB) , ... August 16, 2017 , ... An August 3rd article ... was the subject of a report in JAMA (the Journal of the American Medical Association). ... 50 were able to achieve BMIs under 30, when compared to patients with lower BMIs. ...
    (Date:8/16/2017)... Georgia (PRWEB) , ... August 16, 2017 , ... Greenfield ... growing companies in the U.S. for the second year in a row. The Inc. ... the past three years. , “To be on the list once is a great ...
    (Date:8/16/2017)... Houston, Texas (PRWEB) , ... August 16, 2017 , ... ... Community Credit Union's Stars in the Classroom and will win a visit by a ... in grades K-12 who are at least five years old can visit texanschecking.com/stars to ...
    (Date:8/16/2017)... ... 2017 , ... The Data Council, the leading provider of ... by Advantage Solutions. The Data Council’s IX-ONE platform is the Specialty, Natural ... suppliers, brokers, distributors and retailers. The Data Council will become a part of ...
    Breaking Medicine News(10 mins):
    (Date:8/15/2017)... HOUSTON , Aug. 15, 2017   Mostyn Law ... in Houston, Texas . The Mostyn Law ... the past 2 years. That is why Mostyn Law ... Texas to show its appreciation. Blood supplies ... to fall 5% short of hospital needs in August. That is ...
    (Date:8/15/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO), is now dispensing ... residents. Naloxone is available without a prescription ... G-3320 Beecher Road. ... is intended to block or reverse the effects of ... consciousness. The medication is often carried by first responders ...
    (Date:8/15/2017)... 15, 2017  Axium Pharmaceuticals Inc., the creator of the drug ... the beginning stages of an IPO. The United ... the average cost of a prescription epilepsy drug being $450.00-$1200.00 for a ... AXIUM PHARMACEUTICALS, INC ... Another staggering figure is the fact that Americans spent $42 ...
    Breaking Medicine Technology:
    Cached News: