HOME >> MEDICINE >> NEWS
Research clarifies how Alzheimer's medicines may reduce interference with learning and memory

WASHINGTON -- New evidence clarifies how the only government-approved treatments for mild-to-moderate Alzheimer's Disease may work to improve symptoms. When scientists chemically blocked receptors for an important neurotransmitter called acetylcholine, even healthy young people found it significantly harder to learn and remember especially in the face of interference. This finding may shed light on how cholinesterase inhibitors, FDA-approved drugs that slow the breakdown of acetylcholine in Alzheimer's patients, help alleviate dementia symptoms.

The study appears in the February issue of Behavioral Neuroscience, which is published by the American Psychological Association (APA).

The study demonstrated that acetylcholine helps keep old information from interfering with our ability to learn and remember new information. The findings may help to explain why conditions associated with lower levels of acetylcholine in the brain, such as Alzheimer's disease, Parkinson's disease, dementia due to multiple strokes, multiple sclerosis and schizophrenia cause problems with memory function, as well as the hallucinations and delusions that can occur in some of these conditions.

Conversely, it offers insight into the way that higher acetylcholine levels modestly improve attention, memory, activities of daily living, and behavioral symptoms. Cholinesterase inhibitors boost acetylcholine by reducing the enzyme that breaks it down. Understanding their effects on major symptoms during disease progression may help scientists develop more targeted and effective drugs, as well as to avoid medications that may be detrimental to memory function.

A total of 28 young healthy adults participated in the study. At Massachusetts General Hospital, researchers injected 12 of the study participants with scopolamine, an "anticholinergic" drug used for decades to treat motion sickness and intestinal spasms, and as a sedative and pre-anesthetic before surg
'"/>

Contact: Pam Willenz
public.affairs@apa.org
202-336-5700
American Psychological Association
15-Feb-2004


Page: 1 2 3

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Research offers hope of new treatments for liver damage
3. Research suggests possible blood test for multiple sclerosis
4. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
5. 2005 Award for Basic Research in Biological Mineralization
6. 2005 Craniofacial Biology Research Award
7. 2005 Research in Dental Caries Award
8. 2005 Research in Prosthodontics and Implants Award
9. 2005 Basic Research in Periodontal Disease Award
10. 2005 Research in Oral Biology Award
11. 2005 Pulp Biology Research Award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/24/2019)... , ... March 24, 2019 , ... Few things are ... ways to prevent tooth pain. Paso Robles dentist , Lisa Lu Davis, has ... practices that can help avoid painful conditions. , Pain and soreness from a toothache ...
(Date:3/23/2019)... ... March 22, 2019 , ... ... is pleased to introduce the SkinTyte™ laser treatment at Buckingham Center for Facial ... who recognizes the importance of a beautiful face. Buckingham Center clients are provided ...
(Date:3/23/2019)... ... ... Dr. Srini Pillay , a best-selling author, neuroscientist, tech entrepreneur and an ... ideas on creativity and the processes behind human thinking. His recent book on Amazon, ... in 2017. Now, the acclaimed doctor has some revealing and worrying thoughts on the ...
(Date:3/20/2019)... Texas (PRWEB) , ... March 20, 2019 , ... ... Mobile Medical systems are being developed with Wi-Fi connectivity to allow portable devices ... pumps, heart and hypertension monitoring, glucose monitoring, and other wearable devices for home ...
(Date:3/20/2019)... ... ... GRM Information Management, a leading provider of content services, will exhibit at ... on March 25 and 26. , Texas HIMSS 2019 attendees are encouraged to ... solutions . , GRM offers a range of digital solutions that address the variety ...
Breaking Medicine News(10 mins):
(Date:3/20/2019)... FORT COLLINS, Colo. (PRWEB) , ... March 20, ... ... and green initiatives gather momentum across industries, the healthcare sector has woken up ... as plasticizers present in these products produce a range of toxic effects and ...
(Date:3/20/2019)... (PRWEB) , ... March 20, 2019 , ... ... – featuring DuPont Industrial Biosciences’ DuPont™ INTELLIFRESH™ odor protection technology – that will ... shower curtains and kitchen towels, will be marketed through multiple brand offerings, such ...
(Date:3/20/2019)... (PRWEB) , ... March 20, 2019 , ... ... of companies. A leading third-party retirement plan administration firm specializing in quality retirement ... , As CEO Brad Lankford said, “Latitude is as much an idea as ...
Breaking Medicine Technology:
Cached News: