HOME >> MEDICINE >> NEWS
Research improves treatment of bladder cancer

COLUMBUS, Ohio - Researchers have found a relatively simple way to dramatically improve the cancer-killing capacity of a drug often used to treat superficial bladder cancer.

The changes nearly doubled the number of people who were cancer-free after five years, compared to those receiving the standard therapy, and lengthened the time before tumors recurred in these patients.

The finding is the result of a five-year, international study published in the April 18 issue of the Journal of the National Cancer Institute.

The study looked at ways to improve the use of mitomycin C (MMC) following surgical removal of the tumor. In both the standard and the experimental therapy, MMC is placed in the bladder where it is held by the patient for about two hours.

The new therapy, however, took special measures to maintain a high drug concentration in the bladder.

"We compared the usual way of giving the drug to a new approach, said Jessie L-S Au, distinguished university professor and Dorothy M. Davis Chair in Cancer Research at the College of Pharmacy at Ohio State University.

Patients receiving the experimental treatment went an average of 29.1 months before their cancer recurred, while those receiving the standard treatment had recurrence in 11.3 months.

There was also a statistically significant difference in the number of patients who were recurrence-free after five years: 42.6 percent in the modified treatment versus 23.5 receiving standard treatment.

"We have found a way to make this treatment more effective in a highly significant way," said Au, a researcher with Ohio State's Comprehensive Cancer Center. "We nearly doubled the percentage of patients who were disease-free after five years."

The study, done by Au and a team of researchers, involved 230 patients with confirmed superficial bladder cancer who were at high risk of recurrence. Of these, 111 patients received standard treatment and 119 received the experimental
'"/>

Contact: Jessie L-S Au
Au.1@osu.edu
614-292-4244
Ohio State University
17-Apr-2001


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Research offers hope of new treatments for liver damage
3. Research suggests possible blood test for multiple sclerosis
4. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
5. 2005 Award for Basic Research in Biological Mineralization
6. 2005 Craniofacial Biology Research Award
7. 2005 Research in Dental Caries Award
8. 2005 Research in Prosthodontics and Implants Award
9. 2005 Basic Research in Periodontal Disease Award
10. 2005 Research in Oral Biology Award
11. 2005 Pulp Biology Research Award

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Research improves treatment bladder cancer

(Date:11/28/2014)... 28, 2014 Dr. Diane Walder, one of ... new treatment to her practice called Ultrashape that is designed ... three inches in just six weeks. Ultrashape has been praised ... superior in results when compared to other types of external ... treat it,” said Dr. Walder. , According to Dr. ...
(Date:11/28/2014)... 28, 2014 The Alternative ... over the past five years. The industry has ... therapies that are either alternative to conventional Western ... IBISWorld industry analyst David Whytcross, “industry revenue has ... growing private health insurance membership.” Meanwhile, improving economic ...
(Date:11/28/2014)... THURSDAY, Nov. 27, 2014 (HealthDay News) -- Celebration ... are misused on Thanksgiving Day, experts say. Over ... hot-oil burns have occurred while people were using turkey ... "I have actually cared for a patient who ... should not be done in any circumstances," Dr. Arthur ...
(Date:11/28/2014)... 28, 2014 Not only is the ... free of petroleum, parabens and other cancer-causing agents, but ... research, education and awareness programs that help in the ... owners have raised an incredible, record-breaking contribution of $30,000 ... sales of the Sweet Red Rose Whip Moisturizer and ...
(Date:11/28/2014)... CA (PRWEB) November 28, 2014 ... online, reported during the hugely popular, 2014 MTV ... antismoking organization Truth launched ground-breaking celebrity centered television ... The MTV viewership figures were estimated by ... antismoking ads placed the spotlight on celebrities photographed ...
Breaking Medicine News(10 mins):Health News:Dr. Diane Walder Introduces New Fat Reduction Treatment Called Ultrashape 2Health News:Dr. Diane Walder Introduces New Fat Reduction Treatment Called Ultrashape 3Health News:Alternative Health Therapies in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Alternative Health Therapies in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Alternative Health Therapies in Australia Industry Market Research Report Now Updated by IBISWorld 4Health News:Turkey Fryer Mishaps Can Cause Serious Burns 2Health News:Éminence Organic Skin Care Donates Record-breaking $30,000 to Breast Cancer Research 2Health News:Éminence Organic Skin Care Donates Record-breaking $30,000 to Breast Cancer Research 3Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 2Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 3Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 4Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 5
(Date:11/28/2014)... , Nov. 28, 2014 Aratana Therapeutics, Inc. (NASDAQ: ... on the licensing or acquisition, development and commercialization of ... animals, today announced that it will present at the ... be held December 2-3, 2014, at the New York ... Steven St. Peter , M.D., President ...
(Date:11/28/2014)... , Nov. 28, 2014 Chinese magnesium alloy ... that its biodegradable magnesium alloy bone fixation screw has ... medical apparatus and instrument and that the company ... an interview with Science and Technology Daily ... the company chairman and founder, Professor Li Yangde ...
(Date:11/27/2014)... 2014 Hovione announced today it ... with the U.S. Food and Drug Administration (FDA). This ... improved drug delivery options for established drugs. ... formulation using a new patented crystalline base form of ... prescribed oral antibiotics for acne. Currently, there are no ...
Breaking Medicine Technology:Aratana Therapeutics to Present at the 26th Annual Piper Jaffray Healthcare Conference 2Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 2Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 3Chinese magnesium alloy manufacturer Eontec expects to have its medical magnesium alloy available for clinical trial in 2015 4Hovione Files its First Investigational New Drug Application With the FDA 2
Cached News: