HOME >> MEDICINE >> NEWS
Research improves treatment of bladder cancer

COLUMBUS, Ohio - Researchers have found a relatively simple way to dramatically improve the cancer-killing capacity of a drug often used to treat superficial bladder cancer.

The changes nearly doubled the number of people who were cancer-free after five years, compared to those receiving the standard therapy, and lengthened the time before tumors recurred in these patients.

The finding is the result of a five-year, international study published in the April 18 issue of the Journal of the National Cancer Institute.

The study looked at ways to improve the use of mitomycin C (MMC) following surgical removal of the tumor. In both the standard and the experimental therapy, MMC is placed in the bladder where it is held by the patient for about two hours.

The new therapy, however, took special measures to maintain a high drug concentration in the bladder.

"We compared the usual way of giving the drug to a new approach, said Jessie L-S Au, distinguished university professor and Dorothy M. Davis Chair in Cancer Research at the College of Pharmacy at Ohio State University.

Patients receiving the experimental treatment went an average of 29.1 months before their cancer recurred, while those receiving the standard treatment had recurrence in 11.3 months.

There was also a statistically significant difference in the number of patients who were recurrence-free after five years: 42.6 percent in the modified treatment versus 23.5 receiving standard treatment.

"We have found a way to make this treatment more effective in a highly significant way," said Au, a researcher with Ohio State's Comprehensive Cancer Center. "We nearly doubled the percentage of patients who were disease-free after five years."

The study, done by Au and a team of researchers, involved 230 patients with confirmed superficial bladder cancer who were at high risk of recurrence. Of these, 111 patients received standard treatment and 119 received the experimental
'"/>

Contact: Jessie L-S Au
Au.1@osu.edu
614-292-4244
Ohio State University
17-Apr-2001


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Research offers hope of new treatments for liver damage
3. Research suggests possible blood test for multiple sclerosis
4. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
5. 2005 Award for Basic Research in Biological Mineralization
6. 2005 Craniofacial Biology Research Award
7. 2005 Research in Dental Caries Award
8. 2005 Research in Prosthodontics and Implants Award
9. 2005 Basic Research in Periodontal Disease Award
10. 2005 Research in Oral Biology Award
11. 2005 Pulp Biology Research Award

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/26/2017)... , ... April 26, 2017 ... ... provides an agile ecosystem and domain expertise for sponsors and CROs to ... and trial supply management (RTSM) software platform. Bioclinica AGILE RTSM ...
(Date:4/25/2017)... CA (PRWEB) , ... April 25, 2017 , ... ... access, support, and collaboration, announces Mirroring360 Pro . This new addition to ... comprehensive collaboration experience for education and business. , Mirroring360 Pro enables educators, business ...
(Date:4/25/2017)... , ... April 25, 2017 , ... A stressful work ... work can also decrease overall productivity and performance in the workplace. The goal of ... During the last few weeks of April, Clearview Resolution Services will be shutting down ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... The doctors ... Richmond, BC, who live with dental fear and require sedation to receive dental care. ... at ease during various procedures, from hygienic cleanings to oral surgery, at their dental ...
(Date:4/25/2017)... (PRWEB) , ... April 25, 2017 , ... ... targets, they rely on contracted partners to help with process innovation in drug ... combined drug formulation experience along with state-of-the-art analytical equipment in support of their ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... NEW YORK , April 19, 2017 ... Surgical drainage devices are tubes used to remove excess ... include, blood, serum, pus, urine, bile or lymph. Surgical ... types of surgery such as orthopedics surgery, cardiovascular surgery, ... device is prophylactic post-surgery to prevent accumulation of fluid ...
(Date:4/19/2017)... April 19, 2017 The Global Effective ... to 2022 report has covered and analysed the potential of ... on market size, shares and growth factors. The report identifies ... and opportunities in the global market. ... Browse 152 Tables and Figures, 6 Major Company ...
(Date:4/19/2017)... April 19, 2017  New research provides evidence that an ... according to a study released today that will be presented ... in Boston , April 22 to ... treatment of Parkinson,s disease, the oral drug levodopa has long ... longevity. But as the disease progresses, the effects of the ...
Breaking Medicine Technology:
Cached News: