f Southampton said: "We are facing a huge increase in the numbers of patients with advanced liver fibrosis (scarring) and cirrhosis (end stage scarring of the liver). Currently, we have no effective treatment for liver cirrhosis which is associated with internal bleeding, liver failure and the development of primary liver cancer. There is a huge imperative to develop new approaches to the treatment of liver scarring. Exciting insights such as these will inform the design of future therapies."

Further research into macrophages is set to follow and scientists will explore the role of these immune-system cells in damage and repair to other organs, including the kidney.

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Contact: Makeda Scott
202-588-6523
British Information Services
24-Mar-2005

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