HOME >> MEDICINE >> NEWS
Research questions transplant safety procedure

Lyophilization, a method once thought to inactivate retroviruses such as HIV from bones and connective tissues used in transplant procedures, may not be quite as effective as originally thought, researchers at Michigan State University have concluded.

In a paper to be presented at an upcoming meeting of the American Orthopaedic Society for Sports Medicine, MSU scientists said their research shows the method, known as lyophilization or freeze-drying, does not improve the safety of bones and tissues for transplantation, something that could affect thousands of transplant recipients.

"We were able to demonstrate that this type of tissue processing does not inactivate systemically infected tendon and bone tissues," said Steven P. Arnoczky, the Wade O. Brinker Endowed Professor of Surgery in MSU's College of Veterinary Medicine and one of the lead researchers in the project. "Contrary to currently held clinical beliefs, lyophilization should not be relied upon as an extra measure of security for processing connective tissue allografts."

Bones, ligaments and other tissues that will be used for orthopedic transplants frequently are treated with gamma irradiation or a chemical "cocktail" in an effort to remove any bacteria or viruses which may have evaded the rigorous donor-screening process.

However, these methods can create additional problems, as they sometimes change the tissue's biological and biomechanical properties.

A clinical study published in 1985 suggested that lyophilization may inactivate HIV. Therefore, many surgeons who were seeking an extra measure of protection for their patients would specifically request tissues that had gone through the lyophilization process.

"This has completely changed a long-held belief," Arnoczky said, "and it's a very important contribution, as it got rid of the false sense of security people had with that process."

In their experiment,
'"/>

Contact: Tom Oswald
oswald@msu.edu
517-355-2281
Michigan State University
31-Mar-2004


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Research offers hope of new treatments for liver damage
3. Research suggests possible blood test for multiple sclerosis
4. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
5. 2005 Award for Basic Research in Biological Mineralization
6. 2005 Craniofacial Biology Research Award
7. 2005 Research in Dental Caries Award
8. 2005 Research in Prosthodontics and Implants Award
9. 2005 Basic Research in Periodontal Disease Award
10. 2005 Research in Oral Biology Award
11. 2005 Pulp Biology Research Award

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Research questions transplant safety procedure

(Date:12/21/2014)... 21, 2014 The number of Mirena ... consolidated litigation underway in New Jersey, Bernstein Liebhard LLP ... 1,375 claims involving the birth control IUD have now ... were filed by women who allege spontaneous migration of ... uterine perforations and other complications they were inadequately warned ...
(Date:12/21/2014)... SCI explores disability in sports this ... for disabled athletes with Aaron Scheidies , legally ... called juvenile macular degeneration, where he loses his central ... athletic ambitions to his vision and how he has ... the way for other blind and visually impaired athletes. ...
(Date:12/21/2014)... 2014 Concept Plus, LLC. a SDB ... in Fairfax, VA., today announced it has been recognized ... list, which ranks the fastest growing government contracting small businesses ... 2013. , This is the first year that Concept Plus, ... 20 with a 95.92% compound annual growth rate. “For Concept ...
(Date:12/20/2014)... New York, NY (PRWEB) December 20, 2014 ... with the healthcare sector have benefited the Massage ... Given the discretionary characteristics of industry products, the anticipated ... the five-year period has provided consumers with the means ... adults that have received a massage in a given ...
(Date:12/20/2014)... VogueQueen.com, a leading wedding dress wholesaler and retailer, has ... 2015. Great discounts are now offered on all of ... a discount, up to 80% off, when they place ... 2015. , VogueQueen.com has recently released its new arrival ... Many customers worldwide like VogueQueen’s special designs which feature ...
Breaking Medicine News(10 mins):Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Approach 1,400 in Bergen County Litigation, Bernstein Liebhard LLP Reports 3Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 2Health News:Disability in Sports on SCI TV with Triathlon World Champ Aaron Scheidies 3Health News:Concept Plus, LLC. Named One of Washington Technology’s Fast 50 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:VogueQueen Big Sale Online For The Coming 2015 2
(Date:12/19/2014)... Dec. 18, 2014 Somewhere between dropping five ... was forgotten. But Audicus , a next-generation hearing ... this new year. Hearing loss is the ... population, though it is often unaddressed. Forty-eight million Americans ... a hearing aid, mainly due to price. Hearing aids ...
(Date:12/19/2014)... , Dec. 18, 2014  RESMED INC. (NYSE: ... second quarter of fiscal year 2015 results on Thursday, January ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
(Date:12/19/2014)... China separating membrane market has witnessed robust development ... years, albeit as a later starter. In 2012, the size ... approximated RMB12 billion, with the proportion worldwide soaring to 16.3%. ... membrane market will continue its growth rate by around 20% ... will jump to roughly RMB25 billion. An integrated ...
Breaking Medicine Technology:Audicus Will Help People Resolve to Hear Better in 2015 2ResMed To Announce Second Quarter 2015 Results 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 2Separation Membranes Market (Company, Country & Application) Research Reports for Global and Chinese Regions 3
Cached News: