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Research suggests possible blood test for multiple sclerosis

t can be developed for MS," said Avasarala. "There is probably not a single marker to detect MS. This test was designed to look for a pattern of individual proteins that can differential people with MS from healthy people."

The analysis combined mass spectrometry, a tool for analyzing proteins, with special software to recognize proteins patterns. The technology, known as BAMFTM, was developed by Predictive Diagnostics. Avasarala collaborated Michael Wall and Gershon Wolfe from the company, based in Vacaville, Calif.., to analyze the results.

The findings were presented in April at the American Academy of Neurology's annual meeting. Avasarla is currently collaborating with Wolfe, Wall and Thomas Burger from Innsbruck Medical University, Austria, to analyze 300 patient samples to identify the marker molecules.

MS is a disease of the central nervous system that affects the brain and spinal cord. It strikes an estimated 250,000 people in the United States and is a major acquired neurologic disease in young adults. Common signs and symptoms of MS include fatigue, psychological and cognitive changes, weakness or paralysis of limbs, numbness, vision problems, difficulties speaking or walking, bladder problems, and sexual dysfunction. Wake Forest Baptist cares for more than 2,000 patients with MS.


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Contact: Karen Richardson
krchrdsn@wfubmc.edu
336-716-4587
Wake Forest University Baptist Medical Center
15-Mar-2005


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