HOME >> MEDICINE >> NEWS
Researchers develop MRI technique to study brain anatomy in invertebrates

ATLANTA -- Scientists with the Center for Behavioral Neuroscience, a research consortium based at Georgia State University, have for the first time used a form of magnetic resonance imaging to reveal anatomical features of the nervous system in a live crayfish, a crustacean whose brain measures only 3 millimeters wide.

The technique, which is reported and highlighted in an accompanying commentary in the Dec. 15 issue of The Journal of Experimental Biology, provides a powerful new tool for understanding the neurobiology of behavior in invertebrate animal models.

Conventional MRI technology employs high-intensity magnetic fields to excite protons in the water molecules of soft tissue. Scanners detect the excitation and image cross-sectional slices of an organ, such as the brain. To image a live crayfish, whose physiology does not normally respond to magnetic fields, CBN researchers injected manganese, a contrast-enhancing agent that crayfish cells absorb, through a long tube into its circulatory system. The infusion took place while the animal was positioned inside the MRI scanner.

"Before injecting the manganese, we couldn't see the animal's brain at all," said Georgia State research scientist Jens Herberholz, the study's lead author. "But shortly after injecting it, we suddenly saw the brain light up like a Christmas tree and could easily discern its substructures."

Herberholz and his colleagues, including Georgia State professor Donald Edwards, Georgia State lab technician Christopher Mims, and Emory University's Xiaodong Zhang and Xiaoping Hu, developed manganese-enhanced MRI to study the crayfish brain. They discovered the technique also is effective in imaging other parts of the animal's body. In their pilot study, the scientists imaged a number of complex anatomical structures in the foregut that had never been seen in a live crayfish.

Crayfish serve as one of the best animal models for studyin
'"/>

Contact: Poul Olson
biopeo@langate.gsu.edu
404-463-9433
Georgia State University
15-Dec-2004


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
3. Researchers close in on breast cancer vaccine
4. Researchers discover link between insulin and Alzheimers
5. Researchers model brains electrical storm during a seizure
6. Researchers track programs success in curbing aggressive behavior
7. Researchers confirm Vioxx nearly doubled cardiovascular risks in cancer prevention study
8. Researchers offer emergency workers a lifeline
9. Researchers discover genetic variant that may explain why women develop M.S. more than men
10. Researchers map the sexual network of an entire high school
11. Researchers hope monkeys can provide new insights into depression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2020)... LOS ANGELES (PRWEB) , ... January 23, 2020 , ... ... with Inspired Organics Brand Director, Michelle Berger and Vice President of Dairy ... options. , Inspired Organics is a company that creates organic food and snack options ...
(Date:1/23/2020)... ... January 23, 2020 , ... Merger and acquisition activity in the ... of 2019, according to data from HealthCareMandA.com. The total is the lowest reported in ... when 65 deals were announced. , One deal disclosed a price in the fourth ...
(Date:1/23/2020)... Del. (PRWEB) , ... January 23, 2020 , ... ... coaching and risk services for organizations that operate vehicle fleets in North America ... new subscriber-based e-newsletter, will be published monthly with content accessible on the company’s ...
(Date:1/23/2020)... ... , ... The Incentive Research Foundation is pleased to announce ... segments of the incentives, rewards, and recognition industry, the IRF Board of Trustees ... highlighting the power of incentive and motivational programs. The Board recently met to ...
(Date:1/22/2020)... ... January 22, 2020 , ... In Partnership with the ... dental services for low-income, underinsured individuals at its Largo, FL office on March 7th. ... x-rays , fillings , cleanings and extractions . For more ...
Breaking Medicine News(10 mins):
(Date:1/23/2020)... ... 23, 2020 , ... In the largest genetic sequencing study ... with risk for autism. The study also shows significant progress towards teasing apart ... delay, conditions which often overlap. The study results are published online January 23 ...
(Date:1/23/2020)... (PRWEB) , ... January 23, 2020 , ... ... pain have trusted Australian Dream® for effective relief. Now, the company ... relief. , Australian Dream sought to develop a new design that better communicates ...
(Date:1/23/2020)... Mass. (PRWEB) , ... January 23, 2020 , ... ... of evidence-based clinical resource tools, has announced the availability of a new decision ... Treatment Options presents several pharmacotherapeutic options to manage opioid addiction. , Opioid addiction ...
Breaking Medicine Technology:
Cached News: