HOME >> MEDICINE >> NEWS
Researchers discover that a protein in grape skins can kill cancer cells

CHARLOTTESVILLE, Va., May 25 It's well known that drinking red wine in moderation can have some health benefits, mainly attributed to a compound called resveratrol. Now, scientists at the University of Virginia Health System have discovered how.

They found how resveratrol helps to starve cancer cells by inhibiting the action of a key protein that feeds them. The protein, called nuclear factor- kappa B (NF-kB), is found in the nucleus of all cells and activates genes responsible for cell survival. "We used physiologically-relevant doses of resveratrol and found dramatic effects on human cancer cells," said Marty Mayo, assistant professor of biochemistry and molecular genetics at U.Va.

Mayo said that the resveratrol in one glasses of wine three or four times a week is the right amount to block the protein from feeding cancer cells. Drinking much more than that, however, could stop this affect and, in fact, lead to a greater risk of cancer, he said.

The findings, discovered by Fan Yeung, a postdoctoral fellow at U.Va., are published in the May 20 online edition of the Journal of the European Molecular Biology Organization (EMBO) found at: http://embojournal.npgjournals.com.

Resveratrol is an antioxidant found in a number of plants, including grape skins, raspberries, mulberries and peanuts. Its job in nature is to fight fungus during the rainy season, and it is especially prevalent in grapes used in making red wine. Resveratrol is also sold over-the-counter in the U.S. as a nutritional supplement.

For a number of years, scientists have known that resveratrol acts as an anti-cancer agent, but its role has not been well understood. Mayo and his team demonstrated that cancer cells treated with resveratrol died because they became sensitive to a compound called Tumor Necrosis Factor alpha (TNFa). The U.Va. Health System researchers found that resveratrol initiated a r
'"/>

Contact: Bob Beard
reb8e@virginia.edu
434-982-4490
University of Virginia Health System
25-May-2004


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
3. Researchers close in on breast cancer vaccine
4. Researchers discover link between insulin and Alzheimers
5. Researchers model brains electrical storm during a seizure
6. Researchers track programs success in curbing aggressive behavior
7. Researchers confirm Vioxx nearly doubled cardiovascular risks in cancer prevention study
8. Researchers offer emergency workers a lifeline
9. Researchers discover genetic variant that may explain why women develop M.S. more than men
10. Researchers map the sexual network of an entire high school
11. Researchers hope monkeys can provide new insights into depression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2019)... ... 2019 , ... Kurt Hurley, a veteran marketing executive, joins ... care and occupational medicine, as the healthcare network’s new Chief Marketing Officer. Hurley ... industry developing and implementing integrated marketing communication plans to ensure top line growth ...
(Date:6/24/2019)... Pa. (PRWEB) , ... June 24, 2019 , ... ... for adolescents and adults, today announced the restructuring of the Strategic Advisory Board ... struggling to meet the demand for behavioral health care. , We ...
(Date:6/20/2019)... Okla. (PRWEB) , ... June 20, 2019 , ... ... pleased to announce their partnership with Physical Therapy Solutions in Lawton, which has ... C, the clinic is the group’s 28th clinic in the state. , ...
(Date:6/19/2019)... ... June 19, 2019 , ... The Clean Cooking ... 2018 by the Alliance and its partners. Under the theme “Investment. Innovation. Impact,” ... the clean cooking sector, including an entrepreneur and manufacturer in Africa, a health ...
(Date:6/19/2019)... ... June 19, 2019 , ... Ovation® Fertility scientists have been invited to ... and Embryology (ESHRE) Annual Meeting in Vienna, June 23-26, 2019. , Ovation’s oral ... for both the Basic Science Award for Oral Presentation and the Fertility Society of ...
Breaking Medicine News(10 mins):
(Date:6/24/2019)... ... 2019 , ... Prof. Yitshak Kreiss, Director General of Israel’s Sheba Medical Center ... the Palestinian people as part of a first step in a potential Israeli-Palestinian peace ... invited by U.S. Secretary of the Treasury Mr. Steven Mnuchin to the Peace and ...
(Date:6/20/2019)... ... June 20, 2019 , ... World Trade Center (WTC) responders ... Center site had activated chronic inflammation in their prostates, which may have contributed ... Cancer Research in June. , Inflammation has long been considered an important ...
(Date:6/19/2019)... ... June 19, 2019 , ... Cardiovascular diseases remain the ... all global deaths (17.9 million per year), and are the most expensive condition ... care pathways, treatment and real-time visualization of cardiac anomalies and subsequent therapy more ...
Breaking Medicine Technology:
Cached News: