HOME >> MEDICINE >> NEWS
Researchers discover that a protein in grape skins can kill cancer cells

CHARLOTTESVILLE, Va., May 25 It's well known that drinking red wine in moderation can have some health benefits, mainly attributed to a compound called resveratrol. Now, scientists at the University of Virginia Health System have discovered how.

They found how resveratrol helps to starve cancer cells by inhibiting the action of a key protein that feeds them. The protein, called nuclear factor- kappa B (NF-kB), is found in the nucleus of all cells and activates genes responsible for cell survival. "We used physiologically-relevant doses of resveratrol and found dramatic effects on human cancer cells," said Marty Mayo, assistant professor of biochemistry and molecular genetics at U.Va.

Mayo said that the resveratrol in one glasses of wine three or four times a week is the right amount to block the protein from feeding cancer cells. Drinking much more than that, however, could stop this affect and, in fact, lead to a greater risk of cancer, he said.

The findings, discovered by Fan Yeung, a postdoctoral fellow at U.Va., are published in the May 20 online edition of the Journal of the European Molecular Biology Organization (EMBO) found at: http://embojournal.npgjournals.com.

Resveratrol is an antioxidant found in a number of plants, including grape skins, raspberries, mulberries and peanuts. Its job in nature is to fight fungus during the rainy season, and it is especially prevalent in grapes used in making red wine. Resveratrol is also sold over-the-counter in the U.S. as a nutritional supplement.

For a number of years, scientists have known that resveratrol acts as an anti-cancer agent, but its role has not been well understood. Mayo and his team demonstrated that cancer cells treated with resveratrol died because they became sensitive to a compound called Tumor Necrosis Factor alpha (TNFa). The U.Va. Health System researchers found that resveratrol initiated a r
'"/>

Contact: Bob Beard
reb8e@virginia.edu
434-982-4490
University of Virginia Health System
25-May-2004


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Researchers say breast cancer in Africa may provide clues to the disease in African-Americans
3. Researchers close in on breast cancer vaccine
4. Researchers discover link between insulin and Alzheimers
5. Researchers model brains electrical storm during a seizure
6. Researchers track programs success in curbing aggressive behavior
7. Researchers confirm Vioxx nearly doubled cardiovascular risks in cancer prevention study
8. Researchers offer emergency workers a lifeline
9. Researchers discover genetic variant that may explain why women develop M.S. more than men
10. Researchers map the sexual network of an entire high school
11. Researchers hope monkeys can provide new insights into depression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/17/2019)... ... September 17, 2019 , ... Since the registration ... Century Cures Act in the US, Nocimed has been marketing its unique technology ... images from existing MRI equipment to perform MR spectroscopy, NociScan detects the presence ...
(Date:9/17/2019)... Village, CA (PRWEB) , ... September 17, 2019 ... ... in Westlake Village, CA, incision-free treatment with laser dentistry . A minimally ... to perform than traditional osseous surgery. , Laser dentistry is gentle and ...
(Date:9/17/2019)... ... September 17, 2019 , ... ... largest accountable care organization (ACO) in the country, the company announced today. High-performing ... to improve care quality and increase cost efficiency. This opportunity is open to ...
(Date:9/17/2019)... ... , ... Lubin Austermuehle, P.C. will be one of the sponsors ... held at Found Kitchen and Social House in Evanston on Monday, October 7 from ... Disorder, a rare condition that results from changes to the GRIN2B gene. The GRIN2B ...
(Date:9/17/2019)... ... September 17, 2019 , ... Specialty Technical Publishers (STP) ... Audit Protocol Consortium (IAPC) EHS audit protocol for Japan . Leading companies ... their EHS regulatory obligations and rapidly collect, share, archive, and export audit findings ...
Breaking Medicine News(10 mins):
(Date:9/17/2019)... ... September 17, 2019 , ... Today, in partnership with ... contraception and consent with student and faculty from The City University of New ... Francisco Ramirez, MPH; Elise Schuster, MPH; Raffaele M. Bernardo, DO, FACP, AAHIVS and ...
(Date:9/17/2019)... ... September 17, 2019 , ... Embr Labs , the ... Series B funding led by DigiTx Partners, with participation from Safar Partners, ... use the investment to grow the company’s footprint in wellness and digital therapeutics, accelerate ...
(Date:9/17/2019)... ... September 17, 2019 , ... Gustavo Grodnitzky, PhD will join the ... Yoga Science as holistic mind/body medicine for physicians and other health care professionals. Entitled ... 22-26, 2019 at the Cranwell Resort and Spa in Lenox, Massachusetts, is accredited by ...
Breaking Medicine Technology:
Cached News: