HOME >> MEDICINE >> NEWS
Researchers say breast cancer in Africa may provide clues to the disease in African-Americans

A new review finds similarities between the clinical presentation and course of breast cancer in Africans and African-Americans, suggesting that genetic factors may play a significant role in the racial differences encountered in the epidemiology of breast cancer in America. The article, published in the April 15, 2005 issue of CANCER (http://www.interscience.wiley.com/cancer-newsroom), a peer-reviewed journal of the American Cancer Society, also observes that Africa faces potential increases in breast cancer rates as African women adopt Western reproductive and dietary behaviors that have been shown to increase the risk of breast cancer.

Population studies show while African American women have lower rates of breast cancer than white women in the United States, they have poorer outcomes. African American women are also more likely to get breast cancer at a younger age, and among women in the U.S. under the age of 45, African Americans have the highest incidence rates. African Americans are also more likely to be diagnosed with higher stage disease i.e., estrogen receptor-negative, high-grade tumors that are node-positive. This clinical pattern is similar to that identified in the Ashkenazi populations that led to the discovery of BRCA-1 and -2 gene mutations, prompting many scientists to speculate that there may also be a genetic component contributing to breast cancer in African Americans.

Alero Fregene, M.D. and Lisa A. Newman, M.D., M.P.H. of the University of Michigan Comprehensive Cancer Center conducted an extensive literature review of English-language studies of breast cancer in sub-Saharan Africa. They say understanding the breast cancer burden and clinical characteristics in sub-Saharan Africa, where the majority of African American trace their ancestry from, may contribute to the understanding of racial factors in breast cancer.

The review found current literature,
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
14-Mar-2005


Page: 1 2

Related medicine news :

1. Researchers search for first sign of congestive heart failure
2. Researchers close in on breast cancer vaccine
3. Researchers discover link between insulin and Alzheimers
4. Researchers model brains electrical storm during a seizure
5. Researchers track programs success in curbing aggressive behavior
6. Researchers confirm Vioxx nearly doubled cardiovascular risks in cancer prevention study
7. Researchers offer emergency workers a lifeline
8. Researchers discover genetic variant that may explain why women develop M.S. more than men
9. Researchers map the sexual network of an entire high school
10. Researchers hope monkeys can provide new insights into depression
11. Researchers identify the link between heart failure and weight loss

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... ... PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor ... prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that ... insurance companies have a waiver for care if the client has a cognitive impairment ... family pays for care, is often waived, so the benefits from their insurance start ...
(Date:10/13/2017)... Milford, NJ (PRWEB) , ... October 13, 2017 , ... ... weekend at scenic Alexandria Park in Milford, NJ. This free event, sponsored by ... and physical activity. The fun run is geared towards children of all ages; ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... WILMINGTON, Del. (PRWEB) , ... October 12, 2017 ... ... technology and advisory services for healthcare compliance program management, will showcase a range ... and National Association for Assisted Living (NCAL) Convention and Expo to be held ...
Breaking Medicine News(10 mins):
(Date:10/5/2017)... , Oct. 5, 2017  In response to ... Oral and Maxillofacial Surgeons (AAOMS) released prescribing recommendations ... to be used as a first-line therapy to ... Recognizing the value ... White Paper "Opioid Prescribing: Acute and Postoperative Pain ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, Inc. ... Day Software and Consulting, LLC , and named its ... Software, based in Tennessee , will ... Day expands EnvoyHealth,s service offerings for health care partners ... "In an interoperable world, ...
(Date:10/2/2017)... 2, 2017 The Rebound mobile app is poised ... reverse the tide of prescription drug addiction. The app empowers ... intake and stepping down their dosage in a safe, controlled ... December 2017; the first 100,000 people to sign up will ... http://www.rebound-solution.com/ ...
Breaking Medicine Technology:
Cached News: