Reversing DNA damage caused by the sun before it becomes skin cancer may b...( o the same thing when the dimer is part...)

Reversing DNA damage caused by the sun before it becomes skin cancer may be possible

o the same thing when the dimer is part of a piece of DNA."

The researchers estimate it will be about four months before they are ready to test the enzyme in DNA.

For every drug that makes it to market, "you make about 10,000 compounds," Wiest pointed out. Despite these formidable odds, he is optimistic.

"I'm pretty excited about it. This lays the foundation for a [potential] drug. I think it's promising."

If the artificial enzyme is successful in the upcoming DNA tests, it will likely go through many modifications as it proceeds through further laboratory testing. Then, it would have to be turned over to other researchers for laboratory and clinical studies.

Even if it passes all testing, Jonas estimates that it would be at least ten years or more before a product might come to market that could repair DNA damage caused by the sun.

'"/>

Contact: Charmayne Marsh
202-872-4445
American Chemical Society
5-Apr-2001

Page: 1 2
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