HOME >> MEDICINE >> NEWS
Schizophrenia may be caused by an interaction of genes and viruses in glia cells

A report in the open access journal BMC Psychiatry presents a new hypothesis that may explain the causes of the psychiatric disease, schizophrenia. The hypothesis hinges on glia, a special type of cell, which is important for the maintenance of the connections between brain cells. By re-examining previously published research the authors suggest that schizophrenia may be caused by a combination of defective genes, which result in deficiencies of a variety of growth factors in glia, and infection by viruses, which may further weaken the glia. They conclude that this "weakening" of glia may result in the breakdown of connections between different brain cells leading to the development of schizophrenia.

Schizophrenia is a severe disabling psychiatric disease, which affects approximately 1 percent of the population. People with schizophrenia often suffer terrifying symptoms such as hearing internal voices, feelings of extreme paranoia and an inability to distinguish reality from fantasy. It is clear that schizophrenia has a strong genetic component, however analysis of individual genes alone will not give us a full understanding the causes of schizophrenia.

Irving Gottesman, one of the authors of this paper and originator of the now widely accepted polygenic model of schizophrenia explains,

"The investigation of individual genes in isolation has its limitations since virtually all important biological phenomena, from normal brain functioning to schizophrenia, are the result of complex systems. What is needed is a systems approach for understanding the development of schizophrenia."

This insight motivated Gottesman, and his colleagues Hans Moises and Tomas Zoega, to apply such an approach to previously published results of schizophrenia research.

Human brains are made up of two main types of cells, nerve cells, which carry electrical impulses around the brain and glia, which are important for the normal development of the brain in
'"/>

Contact: Gordon Fletcher
gordon@biomedcentral.com
44-20-7323-0323
BioMed Central
25-Jul-2002


Page: 1 2

Related medicine news :

1. Schizophrenia risk higher in children of older fathers
2. Schizophrenia patients dont take medications regularly
3. Schizophrenia could cause patients to forget their medication
4. Schizophrenia drugs increase risk of cardiac arrest
5. Schizophrenia drugs linked to increased risk of heart attack
6. Schizophrenia has different sub-types linked to problems in different parts of the brain
7. UI Study Finds Social Support May Increase Longevity Of People With Schizophrenia
8. UF Researchers Cite Possible Link Between Autism, Schizophrenia And Diet
9. Schizophrenia-Like Behavior In Rats Blocked Via Glutamate
10. Rat Studies At Yale University School Of Medicine Suggest A New Class Of Medications For Treating Schizophrenia
11. Exercise-induced shortness of breath not always caused by asthma

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... a new practice in Glendale. While the office will be the first ... breast augmentation, tummy tucks, buttock augmentation (Brazilian butt lift), as well as rhinoplasty, ...
(Date:9/1/2020)... ... ... Feeding Matters , the first organization in the world dedicated to advancing the ... that the U.S. Centers for Disease Control and Prevention (CDC) has officially approved PFD ... U.S. International Classification of Diseases (ICD ) on October 1, 2021. ...
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... Surgeon with specialty fellowship training in aesthetic surgery of the face, breast, and ... – the only female-owned premier boutique plastic surgery and aesthetic practice in Southwest ...
(Date:8/31/2020)... ... August 31, 2020 , ... The ... to funding innovative lymphoma research and serving the lymphoma community through a comprehensive ... 10th Anniversary of Blood Cancer Awareness Month (BCAM) and its international Light ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... 1,400 N95 face masks to medical first responders across the United States. Since ... donations of personal protective equipment (PPE) medical centers , hospitals , ...
Breaking Medicine News(10 mins):
(Date:9/3/2020)... FALLS CHURCH, Va. (PRWEB) , ... September 03, 2020 , ... ... a Statistician, An FDAnews Webinar, Thursday, Sept. 17, 2020, 1:30 p.m.-3:00 p.m. EDT, ... were also an expert statistician? , While one can’t become one in 90 ...
(Date:9/2/2020)... ... September 02, 2020 , ... Rigaku Analytical Devices ... discussion among industry professionals about successes and challenges of making changes to their ... Review and will take place on October 15, 2020 at 10:00am PDT ...
(Date:9/2/2020)... Md. (PRWEB) , ... September 02, 2020 , ... ... Dr. Jonathan Lee . Dr. Lee will work at Bethesda Dermatopathology Lab. ... with his B.A. from the University of California, Berkley. He went on to receive ...
Breaking Medicine Technology:
Cached News: