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Scientists Link Body Weight Regulation And Immune System Control

een found in mice, the implications are that the system is the same in mice and humans. "If that turns out to be the case, a new window to the intricate communication grid of the immune system is now opened through a powerful mouse model," says Barsh.

The discovery also poses an intriguing question of basic biology. "Why should immune function be connected to regulation of body weight?" asks Barsh. That remains an open question, but the new research may hold some long-term prospects for the treatment of obesity. "This will obviously require further study, but one might imagine that a subclass of obese patients will be found to have alterations in mahogany-attractin, and that drugs might be developed that affect how mahogany protein functions."


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Contact: Jim Keeley
keeleyj@hhmi.org
301-215-8858
Howard Hughes Medical Institute
11-Mar-1999


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