he speed and direction of the cells changed in response to an encounter with an antigen on another cell membrane. The researchers discovered that T cells traveling about in a random manner switched to a swarming behavior and formed stable clusters following antigenic challenge. That study, which was funded by the National Institute of General Medical Sciences (NIGMS), reveals properties of T- and B-cell behaviors that are critical for initiating immune responses.

NIAID and NIGMS are components of the National Institutes of Health (NIH). NIAID supports basic and applied research to prevent, diagnose, and treat infectious and immune-mediated illnesses, including HIV/AIDS and other sexually transmitted diseases, illness from potential agents of bioterrorism, tuberculosis, malaria, autoimmune disorders, asthma and allergies. NIGMS supports basic biomedical research that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment, and prevention. The Institute's programs encompass the areas of cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, bioinformatics, computational biology, and minority biomedical research and training.

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Contact: Sam Perdue
sp189u@nih.gov
301-402-1663
NIH/National Institute of Allergy and Infectious Diseases
6-Jun-2002

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