Scientists find link between dopamine and obesity

Upton, NY -- Dopamine, a brain chemical associated with addiction to cocaine, alcohol, and other drugs, may also play an important role in obesity. According to a study by scientists at the U.S. Department of Energy's Brookhaven National Laboratory, obese people have fewer receptors for dopamine, a neurotransmitter that helps produce feelings of satisfaction and pleasure. The findings, which will appear in the February 3, 2001 issue of The Lancet, imply that obese people may eat more to try to stimulate the dopamine "pleasure" circuits in their brains, just as addicts do by taking drugs.

"The results from this study suggest that strategies aimed at improving dopamine function might be beneficial in the treatment of obese individuals," says physician Gene-Jack Wang, the lead scientist on the study.

Brookhaven scientists have done extensive research showing that dopamine plays an important role in drug addiction. Among other things, theyve found that addictive drugs increase the level of dopamine in the brain, and that addicts have fewer dopamine receptors than normal subjects.

"Since eating, like the use of addictive drugs, is a highly reinforcing behavior, inducing feelings of gratification and pleasure, we suspected that obese people might have abnormalities in brain dopamine activity as well," says psychiatrist Nora Volkow, who was also involved in the study.

To test this hypothesis, the scientists measured the number of dopamine receptors in the brains of ten severely obese individuals and ten normal controls. Their method consisted of giving each volunteer subject an injection containing a radiotracer, a radioactive chemical "tag" designed to bind to dopamine receptors in the brain. Then, the researchers scanned the subjects' brains using a positron emission tomography (PET ) camera. The PET camera picks up the radioactive signal of the tracer and shows where it is bound to dopamine receptors in the brain. The strength of the signal in

Contact: Dennis Tartaglia
DOE/Brookhaven National Laboratory

Page: 1 2

Related medicine news :

1. Scientists replicate hepatitis C virus in laboratory
2. Scientists identify brain regions that decide where we look
3. Scientists uncover new mechanism for the amygdala in fear recognition
4. Scientists identify protein critical to melanoma growth
5. Scientists discover recipe for life: eating the Polymeal cuts heart disease by 76%
6. Scientists study fish oil diet in bid to cut heart attack risks
7. Scientists discover enzyme crucial to the transportation of proteins within cells
8. Scientists turn on the gender lens on cardiovascular disease research
9. Scientists stalk PPAR-gamma, find novel cancer connection
10. Scientists align billion-year-old protein with embryonic heart defects
11. Scientists pinpoint flaw, offer new promise for stroke treatment

Post Your Comments:

(Date:6/26/2016)... ... 26, 2016 , ... On June 10-11, 2016, A Forever Recovery, a holistic ... World’s Longest Breakfast Table in Battle Creek, MI, where the rehabilitation facility is located. ... some of the world’s leading providers of cereal and other breakfast foods. Its residents ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from the ... AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center in ... topics including advance care planning, healthcare costs and patient and family engagement. , ...
(Date:6/25/2016)... ... 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his ... David Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps ... in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas ... , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated testing ... With this clearance, Roche is the first IVD company ... for sepsis risk assessment and management. PCT ... PCT levels in blood can aid clinicians in assessing ...
(Date:6/23/2016)... 2016 Capricor Therapeutics, Inc. ... biotechnology company focused on the discovery, development and ... enrollment in its ongoing randomized HOPE-Duchenne clinical trial ... of its 24-patient target. Capricor expects the trial ... of 2016, and to report top line data ...
(Date:6/23/2016)... 23, 2016 Bracket , a leading clinical ... generation clinical outcomes platform, Bracket eCOA (SM) 6.0, at ... 26 – 30, 2016 in Philadelphia , ... Outcome Assessment product of its kind to fully integrate with ... Bracket eCOA 6.0 is a flexible platform for electronic clinical ...
Breaking Medicine Technology:
Cached News: