HOME >> MEDICINE >> NEWS
Screening for virus RNA could increase safety of organ & tissue transplantation

This release is also available in German.

Results of a study in this week's issue of THE LANCET suggest that routine screening of blood samples to detect viral RNA among organ and tissue donors who do not have obvious signs of clinical disease would reduce the risk of disease transmission among transplant recipients.

The presence of blood antibodies to viral diseases such as HIV and hepatitis C is the conventional method for assessing whether an individual is safe to be a tissue or organ donor. However this approach is limited; some donors may be infected with a virus but have not yet 'seroconverted' (shown a full immune response to infection by producing antibodies), thereby posing a risk to transplant recipients.

Jean-Michel Pawlotsky (Hpital Henri Mondor, Paris, France) and colleagues determined whether nucleic acid testing (NAT) could detect HIV RNA or hepatitis C virus (HCV) RNA in a large series of seronegative organ and tissue donors, and whether this technique should be routinely used to improve viral safety of grafts. They studied 2236 organ donors, 636 tissue donors, and 177 cornea donors. The investigators identified five HCV RNA-positive donors in 2119 HCV-seronegative organ donors, and one HCV RNA-positive donor in 631 HCV-seronegative tissue donors. No HIV-seronegative, HIV RNA-positive donor was identified.

Dr Pawlotsky comments: "our data, together with the reported cases of HCV transmission to recipients from a seronegative HCV RNA-positive donor, suggest that routine NAT screening of organ and tissue donors might increase viral safety in the transplantation setting. Implementation of systematic NAT screening of tissue (and cell) donors is highly feasible because viral testing can be done every day and can be based on standardised, partly automated, commercial techniques and proceduresTechnical flaws currently hinder routine NAT scree
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
28-Oct-2004


Page: 1 2

Related medicine news :

1. Screening for osteoporosis prevents hip fractures in older adults
2. Screening for genital herpes should be targeted
3. Screening for liver diseases
4. Screening removes West Nile from bood supply
5. Screening for depression at primary level could be next trend in healthcare
6. Screening men for aortic aneurysms justified
7. Screening children for speech problems is ineffective
8. Screening for aortic aneurysms is cost effective
9. Screening the general population for colorectal cancer
10. National Lung Screening Trial
11. Screening reduces mastectomy rates

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: