Second patient with multiple sclerosis undergoes groundbreaking surgery at Yale

New Haven, Conn. A 29-year-old man with multiple sclerosis is the second patient to undergo transplantation surgery at Yale in an effort to repair myelin, the protective brain and spinal cord sheath that is destroyed by the disease, Yale researchers have reported.

The surgery took place in two stages March 6-7 and the patient was discharged from Yale-New Haven Hospital March 10. The young man is the second of five patients who are scheduled to participate in the groundbreaking clinical trial.

"The patient is doing fine," said Timothy Vollmer, M.D., associate professor of neurology at Yale School of Medicine. "He has a high level of disability because of the location of the lesions in the brain, but he is otherwise healthy."

There are an estimated 1.4 million persons worldwide with multiple sclerosis. The young man in the trial suffers from a relapsing form of multiple sclerosis, which Vollmer said is the most common form of multiple sclerosis. It affects three times as many women as men.

Vollmer said he and his team hope to perform the procedure on a third patient next month.

The purpose of the Phase One trial is to determine whether cells found in the bodys peripheral nerves, in this case, the ankle, can safely repair the damaged cells in the brain and spinal cord that result in neurologic disability in patients with multiple sclerosis and other disorders of myelin.

In multiple sclerosis, the immune system attacks the brains nerve fibers and strips away the protective myelin sheath around nerve fibers in the spinal cord and brain. The resulting lesions make it difficult for the nerves to transmit messages.

In the first procedure on March 6, the surgical team harvested Schwann cells from the patients ankle. Animal studies show that Schwann cells can replace the cells that generate the myelin. The second day, the cells were injected into the left posterior aspect of the patients brain, which has lesi

Contact: Jscqueline Weaver
Yale University

Page: 1 2

Related medicine news :

1. Secondhand smoke linked to cervical cancer
2. Second NIAID SARS vaccine candidate helps mice fend off SARS
3. Secondhand smoke impairs lung function in women
4. Second stage of HIV vaccine trial begins in London and Oxford, UK
5. Cholesterol Carriers Better Predictors Than Cholesterol For Second Heart Attack
6. Second Annual AIDS Vaccine Day Honors Volunteers Nationwide
7. Patients Treated Successfully For Hodgkins Disease Are At 9 Times The Risk For Developing Second Cancer
8. Cedars-Sinai Medical Centers Prenatal Program Pushes the Frontiers of Diagnosis From the Second Trimester Into the First
9. AAPS Sponsors Second Frontier Symposium
10. Drug Combination Including New "Super Aspirin" Drug Cuts Risk Of Death Or Second Heart Attack
11. Drugs Effect On Chromosomes May Explain Second Cancers

Post Your Comments:
(Date:12/24/2014)... 24, 2014 The Healthy Home Company has ... raise families. In-Vest USA is dedicated to ... – our first responders. Today, these two organizations have joined ... providing them with body armor through In-Vest’s USA’s Bless the ... that happened this past week in New York. ...
(Date:12/24/2014)... There’s a lot going on with The Affordable Care ... control of the Senate as well as the House, a ... lawsuit has been brought against President Obama by the House, ... have resulted in changes to the law without the approval ... place to weigh the validity of subsidies provided to low ...
(Date:12/24/2014)... “ Relax Melodies ” was featured on NewsWatch ... latest and coolest mobile applications on the iOS, Android, ... and host of NewsWatch, conducted the app review and ... they can fall asleep. , According to the National ... some sort of difficulty sleeping. Since that’s a huge ...
(Date:12/24/2014)... 2014 Dr. Ronald Receveur, a ... placing dental implants in a day, has ... of overusing teeth-whitening treatments. , In his blog ... Dr. Receveur writes that overusing teeth-whitening treatments can lead ... to enamel. , “Because teeth-whitening treatments are ...
(Date:12/24/2014)... year, more than one-third of the more than 10,000 ... extreme heat conditions, according to recent federal statistics. ... the leading cause of heat-related illness among Americans, but ... infections, also put older people at higher risk for ... help health care systems anticipate and perhaps prevent many ...
Breaking Medicine News(10 mins):Health News:The Healthy Home Company and In-Vest USA Team Up to Save the Lives of Law Enforcement 2Health News:Steven Gerst MD Discusses How, Amid Political Opposition, Court Challenges, and a New Open Enrollment Period, the Affordable Care Act still Relies on Health Informatics 2Health News:Steven Gerst MD Discusses How, Amid Political Opposition, Court Challenges, and a New Open Enrollment Period, the Affordable Care Act still Relies on Health Informatics 3Health News:An Application to Help with Insomnia was Featured on NewsWatch Television on December 19, 2014 2Health News:New Albany Dentist Weighs In On New Trend of Overbleaching Teeth 2Health News:New Albany Dentist Weighs In On New Trend of Overbleaching Teeth 3Health News:Heat Stroke, Kidney Failure Help Drive Illnesses From Extreme Heat 2
(Date:12/22/2014)... , Dec. 22, 2014 Apnea Sciences ( ... offices in Aliso Viejo , California.  ... to the tremendous growth and worldwide expansion, a new ... patented SnoreRx, the anti snore cure have exceeded our ... "We are now in 23 countries and will ...
(Date:12/22/2014)... 22, 2014   TRU-D SmartUVC LLC, producers ... robot, announced today that the General Services Administration has ... 2019.   This newly formed agreement will ... of government purchasers, including Department of Veteran Affairs and ... Security contacts purchasing solutions for the Ebola effort in ...
(Date:12/22/2014)... 2014  ConvaTec, a privately-held medical products and technologies ... Interim Chief Executive Officer of the company, effective December ... Berger .  "The Board of Directors of ConvaTec thanks ... the past three years," said Magnus Lundberg , ... confident that the company is well positioned for the ...
Breaking Medicine Technology:TRU-D SmartUVC LLC Awarded General Services Administration Contract to Expand Government Customer Base 2ConvaTec Names Paul Moraviec Interim CEO Effective December 22, 2014 2
Cached News: