Sepsis on the increase in U.S., according to Emory University and CDC study

promoting thrombosis and inhibiting fibrinolysis, which is how the body breaks up clots. These changes may contribute to multiple organ failure, which is a major cause of mortality from sepsis.

Following years of research on sepsis, scientists last year introduced the first effective specific therapy the drug Xigris, which is activated protein C, a recombinant form of a natural anticoagulant. Xigris is effective because it is an anti-coagulant that also reduces inflammation. Before Xigris, the mainstay of therapy was general, broad-spectrum antibiotics and supportive care.

Physicians must be able to recognize sepsis quickly in order to treat it. "Studies show that if you wait even four to eight hours to begin antibiotic therapy, the mortality from sepsis worsens considerably," notes Dr. Martin. "And antibiotics must be appropriate. Patients with severe sepsis are in shock, with organ failure, respiratory failure, and renal failure. Although the mortality with severe sepsis is approximately 30% to 40%, Xigris reduces that to approximately 25%.

Although there has been no scientific study to identify the reasons for the increase in sepsis, Dr. Martin offers several explanations. "Physicians are identifying more cases of sepsis because they are aware of how sepsis differs from other infections," he says. "And sepsis is actually occurring more frequently due to the overuse of antibiotics and the development of resistant organisms. This is apparent in the shift towards gram-positive organisms as the cause of sepsis and the increase in fungal causes. Improvements in care among individuals with altered immunities also could be leading to an increase in sepsis. For example, antiretroviral therapy has led to increased longevity for HIV patients, and we have more patients receiving organ transplants, bone marrow transplants, and high-dose chemotherapy who are vulnerable to infection. An increase in medical and surgical procedures that breach body

Contact: Holly Korschun
Emory University Health Sciences Center

Page: 1 2 3

Related medicine news :

1. Sepsis drug also protects brain cells
2. Sepsis vaccine proves protective in preliminary studies at The Scripps Research Institute
3. Study finds that coordinating care of chronically ill patients does not increase liability
4. Primary care office strategies may increase colon cancer screening
5. Health care report cards may increase racial/ethnic disparities in bypass operations
6. Vitamin E may not prevent cancer or cardiovascular events, but may increase risk for heart failure
7. Study shows acrylamide in baked and fried food does not increase risk of breast cancer in women
8. Postmenopausal breast cancer survivors at increased risk for bone fractures
9. Obesity among African-American stroke survivors increases risk factors for recurrent stroke
10. Computerized order entry systems can increase risk of medication errors
11. Study suggests smoking while pregnant may increase chromosomal abnormalities in fetal cells

Post Your Comments:

(Date:3/28/2020)... MYRTLE BEACH, S.C. (PRWEB) , ... March 27, ... ... regionally renowned orthopedic practice OrthoSC is now offering telemedicine as an ... visit with one of the practice’s doctors in the comfort of their own ...
(Date:3/27/2020)... (PRWEB) , ... March 27, 2020 , ... ... reviewed and approved by NJ Top Docs. Dr. Kubeck has been approved every ... of Orthopaedic Surgery and specializes in Spinal Surgery. , Dr. Kubeck’s medical ...
(Date:3/22/2020)... ... March 21, 2020 , ... ... and the Modular Home Builders Association (MHBA), have been working with state and ... MHBA has been advocating for greater use of modular construction to address the ...
(Date:3/22/2020)... (PRWEB) , ... March 22, 2020 , ... ... self-awareness and mindfulness may appear to be a frivolous luxury. The world’s focus ... and trying to find some sense of stability and control in chaos. However, ...
(Date:3/20/2020)... , ... March 21, 2020 , ... ... and legal communities together for a day of live discussion and learning online. ... advocacy and ethics, telemedicine, whistleblower laws, the role of boards, fraud, waste and ...
Breaking Medicine News(10 mins):
(Date:4/1/2020)... ... April 01, 2020 , ... ... continuing her partnership with the esteemed Haute Beauty network. , The Haute Beauty ... Dr. Green as a leading Anti-Aging Expert. , Haute Beauty offers a prominent ...
(Date:4/1/2020)... ... April 01, 2020 , ... ... producing reusable face shields. As large manufacturers nation-wide scramble to retool their machinery ... reusing masks or in extreme cases, using hand-sewn masks to protect employees from ...
(Date:3/30/2020)... (PRWEB) , ... March 30, 2020 , ... ... announced it has been recognized by Dresner Advisory Services as the #2 vendor ... its capabilities related to data orchestration, data transformation, and data integration for a ...
Breaking Medicine Technology:
Cached News: