HOME >> MEDICINE >> NEWS
Severity of liver disease not a reliable indicator of quality of life

A new study on the determination of how livers are allocated for transplants examined the relationship between liver disease severity and quality of life, and found that the commonly used model for liver allocation is not a reliable indicator of general quality of life.

The results of this study appear in the February 2005 issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS). The journal is published on behalf of the societies by John Wiley & Sons, Inc. and is available online via Wiley InterScience at: http://www.interscience.wiley.com/journal/livertransplantion.

Liver allocation is currently based on a patient's score on the Model for End-Stage Liver Disease (MELD), which uses results of three laboratory tests to predict short-term prognoses of liver disease. Because the MELD score is based on clinical findings, it is believed to be an accurate measure of liver disease severity. However, complications such as hepatic encephalopathy (which involves brain damage, personality changes, and intellectual impairment) and ascites (an accumulation of excess fluid in the abdomen), are not accounted for in the MELD score. MELD is now used in place of the Child-Turcotte-Pugh (CTP) model, which does take into account these complications and therefore is thought to be associated with quality of life.

Led by Sammy Saab, M.D., M.P.H., of the David Geffen School of Medicine at UCLA, the study included 150 adult patients awaiting their first liver transplant at the University of California Los Angeles between July 2003 and May 2004. Liver disease severity was assessed using both the CTP classification and the MELD score. In addition, patients completed two self-administered health-related quality of life questionnaires: the Medical Outcomes Short Form 36 (SF-3
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
21-Jan-2005


Page: 1 2

Related medicine news :

1. Severity of depressed mood affects stroke risk
2. National Study Suggests Heart Attack Severity May Be Declining
3. Research offers hope of new treatments for liver damage
4. Success of liver transplantation may be most influenced by three risk factors
5. Alcohol relapse adversely affects 10-year liver transplant survival
6. Donor age has no affect on long-term liver transplant survival
7. NHS stop-smoking services are insufficient to deliver national smoking targets
8. New ways to design safer & more effective topical (transdermal) drug delivery announced in the PNAS
9. Component of green tea protects injured livers in mice
10. Biochemical marker aids prognosis in liver transplant patients
11. Radiologists offer non-surgical treatment for early-stage liver cancer

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Severity liver disease not reliable indicator quality life

(Date:6/19/2013)... years, Alzheimer,s researchers have focused on two proteins that ... may contribute to the disease: plaques made up of ... tau. , But for the first time, an Alzheimer,s ... independently, but at the interaction of the two proteins ... post-mortem Alzheimer,s patients and in mouse brains with Alzheimer,s ...
(Date:6/19/2013)... that the incidence of cancer is many fold higher ... have an inadequate understanding on how best to treat ... are occasionally included in clinical trials, those elderly patients ... patients. Thus, the broader elderly patient population is not ... the Elderly Task Force is now starting a new ...
(Date:6/19/2013)... IL (PRWEB) June 19, 2013 Chicago is ... the 31st, 48th and 50th Chicago Wards will require landlords ... – or face fines. The ordinance also makes ... complying with all treatment requests – which often include disposing ... pest control company Orkin reported that it did more bed ...
(Date:6/19/2013)... The Cancer Support Community (CSC), an international nonprofit organization, ... whole patient with the launch today of the Cancer ... event, held at the Newseum, will feature a keynote ... members who have made a significant impact on cancer ... engaged in the cancer journey. , ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 A brain ... for those closest to them. The sudden onset of ... brain tumor has on a patient’s behavioral and cognitive ... both the patient and family. The American Brain ... July 26 and Saturday, July 27 in Chicago, focuses ...
Breaking Medicine News(10 mins):Health News:New Alzheimer's research suggests possible cause: The interaction of proteins in the brain 2Health News:EORTC study opens for elderly patients with HER-2 positive metastatic breast cancer 2Health News:Chicago Ordinance Requires Landlords and Tenants to Take Responsibility for Bed Bugs 2Health News:Keeping the Promise of Cancer Care for the Whole Patient 2Health News:Keeping the Promise of Cancer Care for the Whole Patient 3Health News:American Brain Tumor Association Conference Advances Holistic Approach to Living with a Brain Tumor 2Health News:American Brain Tumor Association Conference Advances Holistic Approach to Living with a Brain Tumor 3
(Date:6/19/2013)... , June 19, 2013  This year alone, The ... 300 research projects with one goal in mind: Discovering ... "Team In Training" (TNT), a flagship LLS fundraising campaign ... program, is marking its landmark 25 th anniversary. ... $875 million in research to discover and deliver breakthrough ...
(Date:6/19/2013)... , June 19, 2013 Today MedeAnalytics, ... introduced the next-generation of its Employer Group ... health plans to provide their employer groups an ... factors, medical and prescription drug claims, network utilization, ... http://photos.prnewswire.com/prnh/20100621/SF23660LOGO ) "Employer Group ...
(Date:6/18/2013)... MILAN , June 19, 2013 ... in fluctuating Parkinson,s disease (PD) patients as add-on ... clinically important improvement in motor symptoms in fluctuating ...   Newron Pharmaceuticals S.p.A. ("Newron"), a ... and pain therapies, and its partner Zambon S.p.A., ...
Breaking Medicine Technology:Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 2Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 3Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 4Celebrating 25 Years and Counting: Leukemia and Lymphoma Society's "Team In Training" Goes the Distance and Beyond for Blood Cancer Patients 5MedeAnalytics Introduces Next-Generation Employer Group and Individual Business Analytics Solution 2Safinamide Phase III Study Results Presented at 2013 MDS Meeting 2Safinamide Phase III Study Results Presented at 2013 MDS Meeting 3Safinamide Phase III Study Results Presented at 2013 MDS Meeting 4Safinamide Phase III Study Results Presented at 2013 MDS Meeting 5Safinamide Phase III Study Results Presented at 2013 MDS Meeting 6
Cached News: