HOME >> MEDICINE >> NEWS
Should Doctors Urge Patients To Take Breaks From Their Drugs?

It sounds like madness, but some AIDS researchers think that HIV-infected people may benefit if they take repeated "holidays" from their drug treatments.

Cocktails of drugs that disable two key viral enzymes have transformed the lives of people with HIV, allowing some patients to rise from their sick beds. But several AIDS experts now suggest that a sequence of two-week breaks from this "triple therapy" may boost a vital component of the immune response.

The component in question is the cytotoxic T lymphocyte (CTL) response. These white blood cells kill other cells that are infected by a virus, and so are at the vanguard of the body's battle against HIV.

Treatment holidays were debated at last month's Chicago Conference on Retroviruses and Opportunistic Infections. Franco Lori of the Research Institute for Genetic and Human Therapy in Washington DC described a patient in Berlin who started treatment with three types of anti-HIV drug soon after becoming infected. The therapy was interrupted twice due to medical complications, and subsequently stopped altogether. Two years on, levels of HIV in his blood are negligible.

Lori thinks the breaks in treatment allowed a CTL response strong enough to contain the virus. He is conducting tests on monkeys and so far his results back this theory. Animals infected with SIV, a related virus, have kept it at undetectable levels in their blood for 145 days after several stop-start triple therapy treatments.

However, anecdotal reports and animal experiments aren't enough to overturn the AIDS orthodoxy. "We now need randomised controlled trials," says Lori.

Bruce Walker of Harvard Medical School in Boston is starting a small trial to see if the immune system can be trained to keep HIV under control by stopping patients' triple therapy several times for periods of about two weeks, leaving a month or so between each treatment holiday. He will study patients who
'"/>

Contact: Claire Bowles
claire.bowles@rbi.co.uk
44-171-331-2751
New Scientist
24-Mar-1999


Page: 1 2

Related medicine news :

1. Should medical students have earlier contact with patients?
2. Should nurses conduct breast cancer follow-up visits?
3. Should compulsory screening of immigrants be part of UK public health policy?
4. Should the standard guidelines for assessing prostate cancer control be changed?
5. Should living liver donation be available in the NHS?
6. Should ambulance crews perform emergency breathing procedure?
7. C-reactive proteins: Should everyone be tested?
8. Should people with dementia be electronically tagged?
9. Should we help to create disabled babies?
10. Should people with diabetes sleep with the lights on?
11. Should women be screened for domestic violence?

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/17/2019)... ... September 17, 2019 , ... Since the registration ... Century Cures Act in the US, Nocimed has been marketing its unique technology ... images from existing MRI equipment to perform MR spectroscopy, NociScan detects the presence ...
(Date:9/17/2019)... Village, CA (PRWEB) , ... September 17, 2019 ... ... in Westlake Village, CA, incision-free treatment with laser dentistry . A minimally ... to perform than traditional osseous surgery. , Laser dentistry is gentle and ...
(Date:9/17/2019)... ... September 17, 2019 , ... ... largest accountable care organization (ACO) in the country, the company announced today. High-performing ... to improve care quality and increase cost efficiency. This opportunity is open to ...
(Date:9/17/2019)... ... , ... Lubin Austermuehle, P.C. will be one of the sponsors ... held at Found Kitchen and Social House in Evanston on Monday, October 7 from ... Disorder, a rare condition that results from changes to the GRIN2B gene. The GRIN2B ...
(Date:9/17/2019)... ... September 17, 2019 , ... Specialty Technical Publishers (STP) ... Audit Protocol Consortium (IAPC) EHS audit protocol for Japan . Leading companies ... their EHS regulatory obligations and rapidly collect, share, archive, and export audit findings ...
Breaking Medicine News(10 mins):
(Date:9/17/2019)... ... September 17, 2019 , ... Today, in partnership with ... contraception and consent with student and faculty from The City University of New ... Francisco Ramirez, MPH; Elise Schuster, MPH; Raffaele M. Bernardo, DO, FACP, AAHIVS and ...
(Date:9/17/2019)... ... September 17, 2019 , ... Embr Labs , the ... Series B funding led by DigiTx Partners, with participation from Safar Partners, ... use the investment to grow the company’s footprint in wellness and digital therapeutics, accelerate ...
(Date:9/17/2019)... ... September 17, 2019 , ... Gustavo Grodnitzky, PhD will join the ... Yoga Science as holistic mind/body medicine for physicians and other health care professionals. Entitled ... 22-26, 2019 at the Cranwell Resort and Spa in Lenox, Massachusetts, is accredited by ...
Breaking Medicine Technology:
Cached News: