HOME >> MEDICINE >> NEWS
Simple sputum test for confirmation of childhood tuberculosis

Results of a South African study in this week's issue of THE LANCET show how a diagnosis of tuberculosis in young children can be confirmed by a straightforward sputum test, rather than the conventional and invasive procedure of gastric lavage.

Diagnosis of tuberculosis is difficult in infants and young children and can be complicated by HIV infection. Heather Zar (School of Child and Adolescent Health, University of Cape Town, South Africa) and colleagues studied 250 children aged 1 month to 5 years who were admitted for suspected pulmonary tuberculosis in Cape Town. Sputum induction and gastric lavage were done on three consecutive days according to a standard procedure.

Samples from induced sputum and gastric lavage were positive in 87% and 65% of children, respectively. The yield from one sample from induced sputum was similar to that from three gastric lavages. In addition, almost half of all culture positive sputum samples were also smear positive, enabling rapid diagnosis and initiation of treatment. There was no difference in the reliability of diagnosis between HIV-positive and HIV-negative children. Sputum induction was useful even in young infants, with almost 40% of children with a positive sputum culture being less than one year of age.

Professor Zar comments: "In children with suspected pulmonary tuberculosis, sputum induction, not gastric lavage, should be the standard technique for microbiological diagnosis. One sample is sufficient, but if resources allow and if the child is in hospital, two or three specimens can increase microbiological yieldThe important clinical usefulness of sputum induction for diagnosis of tuberculosis in this study raises possibilities for its use in primary care, and for diagnosis of other respiratory diseases in infants and young children."

In a Research Letter (p 150), Daniel Vargus and colleagues present a preliminary comparison of the string test--where the removal of swallowed string
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
6-Jan-2005


Page: 1 2 3

Related medicine news :

1. Simple intervention encourages sun protection behaviors
2. Simple blood test may help to predict cardiovascular risk in older women
3. Simple question from your doctor can help identify your risk for breast cancer
4. Simple treatment could prevent many child malaria deaths
5. Simpler blood thinning medication effective for preventing blood clots and stroke
6. Simpler alphabet guidelines for treating acute coronary syndrome reduce risk
7. Simple intervention nearly eliminates catheter-related bloodstream infections
8. Simple interventions for accident and emergency patients could help reduce excessive drinking
9. Simple tests could signal and prevent heart disease in women, says Pittsburgh researcher
10. Simpler, cheaper way to make and fit prosthetics developed
11. Simple, easy acts in pregnancy and childbirth might protect against incontinence

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
Cached News: