HOME >> MEDICINE >> NEWS
Simpler blood thinning medication effective for preventing blood clots and stroke

CHICAGO - A medication that could simplify anticoagulation therapy, ximelagatran, was found to be as effective as other common therapies for preventing stroke and recurrent blood clots, according to studies in the February 9 issue of JAMA. Ximelagatran is currently approved for use in some European countries but it has not been approved in the United States because of concerns about adverse effects.

In the first study, Jean-Noel Fiessinger, M.D., of Hpital Europen Georges Pompidou, Paris, and colleagues conducted a study of patients with deep vein thrombosis (blood clot in veins of the legs, pelvis or arms) to determine the efficacy and safety of oral ximelagatran compared to standard treatment with the anticoagulants enoxaparin and warfarin.

According to background information in the article, current therapy for patients with acute venous thromboembolism consists of 5 to 7 days of the anticoagulant heparin overlapped with and followed by long-term, oral anticoagulation with a therapy such as warfarin. Heparin must be given parenterally (by injection, usually through the veins) and administration requires considerable health care resources. Warfarin is given orally, but has an unpredictable dose response, interacts with many drugs, and can be affected by changes in diet; thus, continued coagulation monitoring and dose adjustment are necessary. Ximelagatran is administered orally and is rapidly absorbed and quickly converted to its active form.

The trial (Thrombin Inhibitor in Venous Thromboembolism [THRIVE] Treatment Study) included 2,489 patients with deep vein thrombosis. The study was conducted at 279 centers in 28 countries from September 2000 through December 2002. Patients were randomized to receive 6 months of treatment with either oral ximelagatran, twice daily, or subcutaneous enoxaparin, twice daily for 5 to 20 days followed by warfarin.

The researchers found that the primary efficacy end point of recurrent venous thromboe
'"/>

Contact: Bruce L. Davidson, M.D.
206-215-2500
JAMA and Archives Journals
8-Feb-2005


Page: 1 2 3 4 5

Related medicine news :

1. Simpler alphabet guidelines for treating acute coronary syndrome reduce risk
2. Simpler, cheaper way to make and fit prosthetics developed
3. Progress In Cancer-Vaccine Studies: Simpler, Safer Approach Producing Encouraging Results
4. A marker for new blood vessel formation in tumors
5. Acupuncture found to lower elevations in blood pressure
6. Diagnostic test for range of blood disorders on the horizon
7. Research suggests possible blood test for multiple sclerosis
8. Epstein-Barr virus protein crucial to its role in blood cancers
9. Simple blood test may help to predict cardiovascular risk in older women
10. Drug that hinders blood vessel growth under study in ovarian cancer
11. Laughter helps blood vessels function better

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/11/2018)... ... October 11, 2018 , ... Four weeks ... to manipulation,” warns former U.S. Department of Homeland Security deputy assistant secretary Paul ... How We Can Stop it. , Pointing to the ability of Russian hackers ...
(Date:10/6/2018)... , ... October 06, 2018 , ... ... for healthcare treatment professionals who treat the full spectrum of eating disorders (ED), ... organization’s Presidents Council. , “As with each of our Presidents Council members, it ...
(Date:10/5/2018)... ... October 05, 2018 , ... Shofner Vision ... surgery to patients residing in middle Tennessee and surrounding areas. Recognized by his ... States, Dr. Stewart Shofner has performed over 40,000 LASIK procedures and ...
(Date:10/5/2018)... ... ... The American Orthopaedic Society for Sports Medicine ( AOSSM ) is proud ... passage of the Sports Medicine Licensure Clarity Act (H.R.302) which was signed into law ... legal protection for traveling team physicians and safeguards injured athletes’ timely access to the ...
(Date:10/5/2018)... ... October 05, 2018 , ... ... healthcare professionals through an all-digital platform, today announced the launch of ... , "This is a unique and easy-to-use educational tool for all rheumatologists,” ...
Breaking Medicine News(10 mins):
(Date:10/13/2018)... ... October 13, 2018 , ... As news hits that ... cent over the next five years, from $3200 million in 2017 to $7170 million ... could even help drive this growth further. This news comes hot on the heels ...
(Date:10/11/2018)... ... October 11, 2018 , ... In the last four months it has ... families and allowance of six more in USA, China and Japan from three other ... MRI safety and security products. , The patents assigned from QinetiQ include US 7113092, ...
(Date:10/6/2018)... OBISPO, Calif. (PRWEB) , ... October 06, 2018 , ... ... surgery or an injury. Carol Rowsemitt, PhD, RN, FNP-C, a San Luis Obispo ... losing weight. She understands this better than most dietitians. , Rowsemitt specializes in helping ...
Breaking Medicine Technology:
Cached News: