HOME >> MEDICINE >> NEWS
Simpler blood thinning medication effective for preventing blood clots and stroke

CHICAGO - A medication that could simplify anticoagulation therapy, ximelagatran, was found to be as effective as other common therapies for preventing stroke and recurrent blood clots, according to studies in the February 9 issue of JAMA. Ximelagatran is currently approved for use in some European countries but it has not been approved in the United States because of concerns about adverse effects.

In the first study, Jean-Noel Fiessinger, M.D., of Hpital Europen Georges Pompidou, Paris, and colleagues conducted a study of patients with deep vein thrombosis (blood clot in veins of the legs, pelvis or arms) to determine the efficacy and safety of oral ximelagatran compared to standard treatment with the anticoagulants enoxaparin and warfarin.

According to background information in the article, current therapy for patients with acute venous thromboembolism consists of 5 to 7 days of the anticoagulant heparin overlapped with and followed by long-term, oral anticoagulation with a therapy such as warfarin. Heparin must be given parenterally (by injection, usually through the veins) and administration requires considerable health care resources. Warfarin is given orally, but has an unpredictable dose response, interacts with many drugs, and can be affected by changes in diet; thus, continued coagulation monitoring and dose adjustment are necessary. Ximelagatran is administered orally and is rapidly absorbed and quickly converted to its active form.

The trial (Thrombin Inhibitor in Venous Thromboembolism [THRIVE] Treatment Study) included 2,489 patients with deep vein thrombosis. The study was conducted at 279 centers in 28 countries from September 2000 through December 2002. Patients were randomized to receive 6 months of treatment with either oral ximelagatran, twice daily, or subcutaneous enoxaparin, twice daily for 5 to 20 days followed by warfarin.

The researchers found that the primary efficacy end point of recurrent venous thromboe
'"/>

Contact: Bruce L. Davidson, M.D.
206-215-2500
JAMA and Archives Journals
8-Feb-2005


Page: 1 2 3 4 5

Related medicine news :

1. Simpler alphabet guidelines for treating acute coronary syndrome reduce risk
2. Simpler, cheaper way to make and fit prosthetics developed
3. Progress In Cancer-Vaccine Studies: Simpler, Safer Approach Producing Encouraging Results
4. A marker for new blood vessel formation in tumors
5. Acupuncture found to lower elevations in blood pressure
6. Diagnostic test for range of blood disorders on the horizon
7. Research suggests possible blood test for multiple sclerosis
8. Epstein-Barr virus protein crucial to its role in blood cancers
9. Simple blood test may help to predict cardiovascular risk in older women
10. Drug that hinders blood vessel growth under study in ovarian cancer
11. Laughter helps blood vessels function better

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/13/2019)... ... January 12, 2019 , ... On December 13th, The Pennsylvania ... hosted a continuing education (CEU) event entitled, Can You Hear Me Now? Creating ... a series of talks to help develop and cultivate the relationship between mentors ...
(Date:1/11/2019)... ... January 11, 2019 , ... In Partnership with the ... services for low-income, underinsured individuals at its Burleson, TX office on February ... x-rays, fillings, cleanings and extractions . For more information, please visit ...
(Date:1/11/2019)... DETROIT (PRWEB) , ... January 11, 2019 , ... ... partnership with Detroit AM radio station, WJR-760. , Dr. Jonathan Zaidan, President of ... Ann Thomas airing on the third Wednesday of each month at 7pm. , ...
(Date:1/10/2019)... ... ... January 8, Dr. Samuel Joseph, Jr. , assisted by Dr. Andrew Moulton ... revolutionary 3D Printed Aries Titanium Spinal Implant . “As a surgeon, it’s very ... so quickly,” commented Dr. Joseph, founder of Joseph Spine. “Today we were able to successfully ...
(Date:1/10/2019)... ... January 10, 2019 , ... GoGreen ... Tencel CBD Infused Face Mask. CBD, or Cannabidiol, is one of many cannabinoids ... shown that CBD influences receptors that are naturally present in the body to ...
Breaking Medicine News(10 mins):
(Date:1/10/2019)... (PRWEB) , ... January 10, 2019 , ... ... to introduce the new A-Series Advantage Anesthesia Delivery platform, providing a modular, state-of-the-art ... A7 Advantage systems, enabling Mindray to continue its unwavering commitment to perioperative care. ...
(Date:1/8/2019)... ... January 08, 2019 , ... University ... a UroLift® Center of Excellence. The designation recognizes that Dr. Jaeger has achieved ... a commitment to exemplary care for men suffering from symptoms associated with benign ...
(Date:1/8/2019)... ... January 08, 2019 , ... “A baby is born ... can change that alarming statistic,” said Christina Chambers, PhD, MPH, President of MotherToBaby, ... is joining with leading prenatal health experts from the National Birth Defects Prevention ...
Breaking Medicine Technology:
Cached News: