HOME >> MEDICINE >> NEWS
Simpler blood thinning medication effective for preventing blood clots and stroke

CHICAGO - A medication that could simplify anticoagulation therapy, ximelagatran, was found to be as effective as other common therapies for preventing stroke and recurrent blood clots, according to studies in the February 9 issue of JAMA. Ximelagatran is currently approved for use in some European countries but it has not been approved in the United States because of concerns about adverse effects.

In the first study, Jean-Noel Fiessinger, M.D., of Hpital Europen Georges Pompidou, Paris, and colleagues conducted a study of patients with deep vein thrombosis (blood clot in veins of the legs, pelvis or arms) to determine the efficacy and safety of oral ximelagatran compared to standard treatment with the anticoagulants enoxaparin and warfarin.

According to background information in the article, current therapy for patients with acute venous thromboembolism consists of 5 to 7 days of the anticoagulant heparin overlapped with and followed by long-term, oral anticoagulation with a therapy such as warfarin. Heparin must be given parenterally (by injection, usually through the veins) and administration requires considerable health care resources. Warfarin is given orally, but has an unpredictable dose response, interacts with many drugs, and can be affected by changes in diet; thus, continued coagulation monitoring and dose adjustment are necessary. Ximelagatran is administered orally and is rapidly absorbed and quickly converted to its active form.

The trial (Thrombin Inhibitor in Venous Thromboembolism [THRIVE] Treatment Study) included 2,489 patients with deep vein thrombosis. The study was conducted at 279 centers in 28 countries from September 2000 through December 2002. Patients were randomized to receive 6 months of treatment with either oral ximelagatran, twice daily, or subcutaneous enoxaparin, twice daily for 5 to 20 days followed by warfarin.

The researchers found that the primary efficacy end point of recurrent venous thromboe
'"/>

Contact: Bruce L. Davidson, M.D.
206-215-2500
JAMA and Archives Journals
8-Feb-2005


Page: 1 2 3 4 5

Related medicine news :

1. Simpler alphabet guidelines for treating acute coronary syndrome reduce risk
2. Simpler, cheaper way to make and fit prosthetics developed
3. Progress In Cancer-Vaccine Studies: Simpler, Safer Approach Producing Encouraging Results
4. A marker for new blood vessel formation in tumors
5. Acupuncture found to lower elevations in blood pressure
6. Diagnostic test for range of blood disorders on the horizon
7. Research suggests possible blood test for multiple sclerosis
8. Epstein-Barr virus protein crucial to its role in blood cancers
9. Simple blood test may help to predict cardiovascular risk in older women
10. Drug that hinders blood vessel growth under study in ovarian cancer
11. Laughter helps blood vessels function better

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2019)... ... May 23, 2019 , ... Smashtech has ... this honor for the third year in a row. , Hitting newsstands May ... the list is the result of a wide-ranging and comprehensive measurement of private American ...
(Date:5/23/2019)... ... 2019 , ... Dr. Earl Stephenson, board-certified Face Expert representing ... Beauty Network, well known for their exclusivity, and luxurious lifestyle, is privileged to ... the Haute Living partnership. , Haute Beauty offers a prominent collective of leading ...
(Date:5/23/2019)... ... May 23, 2019 , ... Arasan Chip Systems announces the immediate availability its ... v.1.2 IP supporting speeds of upto 3.5 Gsps symbol rate per lane (equivalent ... 4.5 Gbps data rate per lane. With this latest CSI IP v2.1, provides a ...
(Date:5/23/2019)... ... May 23, 2019 , ... Carrie Romandine, RevSpring’s vice president of ... Women in Healthcare IT . , This is the fourth year that HDM ... given to women in the following professional categories:, CIOs/HIT ...
(Date:5/23/2019)... EDWARDSVILLE, Ill. (PRWEB) , ... May 23, 2019 , ... ... Dr. Dennis “Denny” Savoca will address 58 SDM students receiving their doctor of dental ... the SIUE Morris University Center Meridian Ballroom. The commencement ceremony can be viewed live ...
Breaking Medicine News(10 mins):
(Date:5/24/2019)... ... ... Amare Global is a finalist in two categories in the NutraIngredients-USA ... (Amare Global) and Probiotic Product of the Year ( Amare’s Kids FundaMentals ). ... on the emerging science of the microbiome and the gut-brain axis is not just ...
(Date:5/23/2019)... ... 2019 , ... More than 20 trauma survivors and their families gathered at ... responders and community partners. The theme for the program called “Firearm, Injury Prevention Every ... their support and stories, continue healing and say thank you to their caregivers. The ...
(Date:5/23/2019)... ... May 23, 2019 , ... ... arterial hypertension (PAH), today announced the presentation of positive data from a multi-center ... pulmonary arterial hypertension (PAH) who are on a stable regimen of dual-oral combination ...
Breaking Medicine Technology:
Cached News: