Smallpox vaccine may cause harmless skin rashes

People who have never received a smallpox vaccination may develop any of a variety of benign skin rashes a few days after getting vaccinated for smallpox that should not be confused with a more serious complication of the vaccine, according to an article in the April 1 issue of Clinical Infectious Diseases, now available online.

Vaccinia is a virus used to immunize people against smallpox. The study examined 350 adult volunteers, 250 of whom were "vaccinia-nave," or had never been vaccinated for smallpox before, and 100 of whom were "vaccinia-experienced," or had previously received a smallpox vaccination. Of the vaccinia-nave, 3.6 percent developed some type of skin rash 6-19 days after being vaccinated. Symptoms usually included itching, redness and small bumps on the skin, and some patients also complained of headaches.

The five different types of rashes described in the article were all "self-limiting"--that is, they cleared up on their own after one to three weeks--and were not accompanied by fever or any other serious symptoms. The harmlessness of the vaccinia-associated skin rashes makes the findings important, according to Dr. Richard Greenberg, lead author of the study, which took place from July of 2002 to February of 2003.

"Physicians need to know that [the skin reactions] are benign and can be treated with medicines such as antihistamine," said Dr. Greenberg of the University of Kentucky School of Medicine. Doctors who realize that the rashes are not dangerous can offer reassurance to concerned patients and prescribe appropriate medications for symptom relief.

A physician who is unaware of the possibility for a benign skin reaction might wrongly assume that a patient's rash was the development of one of the more dangerous vaccinial lesions. "The concern is that the physician would overreact," Dr. Greenberg said. "These skin reactions are rather dramatic, and if we're going to be vaccinating against smallpox, the physicia

Contact: Diana Olson
Infectious Diseases Society of America

Page: 1 2

Related medicine news :

1. Smallpox vaccine can be diluted and still be effective, expanding supply if needed
2. Smallpox outbreak response: Targeted vaccination may be almost as effective as mass vaccination
3. Pitt marks 50th anniversary of its Salk polio vaccine with reunion, scientific symposium
4. NIAID initiates trial of experimental avian flu vaccine
5. Study finds majority of women willing to accept cervical cancer vaccine for self and children
6. Invasive pneumonia and antibiotic resistance decreased after childhood vaccine introduced
7. Earlier use of prostate cancer vaccines urged by Hopkins scientists
8. Researchers close in on breast cancer vaccine
9. EuroVacc 02 HIV vaccine trial begins in February 2005
10. Varicella vaccine effective on chicken pox; Impact on herpes zoster unclear
11. Pathogen-mimicking vaccine as strategy for cancer therapy

Post Your Comments:

(Date:10/12/2015)... ... October 12, 2015 , ... ... secured a new corporate headquarters, located at 485 Madison Avenue, New York, NY ... and increased emphasis on cloud-based technology. , “Care to Care is a dynamic ...
(Date:10/12/2015)... ... October 12, 2015 , ... In the first known ... individuals involved in nursing research spent as much as the equivalent of four 40-hour ... a single successful National Institutes of Health (NIH) grant application for funds to conduct ...
(Date:10/12/2015)... ... October 12, 2015 , ... CMS’s just-released 2016 Medicare ... partners to assess and act on, indicating which stars measures are causing plans the ... Part D health plans should focus their efforts and how CMS intends to modify ...
(Date:10/12/2015)... ... October 12, 2015 , ... T.E.N., a technology ... evening, October 8, at the 2015 ISE® Northeast Executive Forum and Awards ... , Michael Towers, VP, executive information security officer for Allergan, was selected as ...
(Date:10/12/2015)... ... October 12, 2015 , ... On Sunday, October 18, the Sierra Regional Spine ... in support of all Washoe County students. This is the first time the institute ... Sparks Marina outlet mall outside Reno, Nevada. , The family and youth-focused event features ...
Breaking Medicine News(10 mins):
(Date:10/12/2015)... 12, 2015 The global infertility treatment ... million by 2020 from USD 1,822.32 million in ... and 2020. By product, the market includes antivibration ... systems, micromanipulator systems, ovum aspiration pumps, sperm analyzer ... market is segmented into in vitro fertilization, artificial ...
(Date:10/12/2015)... , Oct. 12, 2015  CME Group,s Center for ... and CEO of Theranos, is the 11 th recipient ... founded the revolutionary blood diagnostics company, Theranos , to ... usher in a new era of preventive care. CME Group ... Financial Leadership Conference in Naples, Florida ...
(Date:10/12/2015)... October 12, 2015 ... Pipeline Review, H2 2015 market research report provides ... pipelines by identifying new targets and MOAs to ... . --> http://www.rnrmarketresearch.com/plague-pipeline-review-h2-2015-market-report.html . ... spread across 62 pages, analyzing 6 companies, 8 ...
Breaking Medicine Technology:
Cached News: