HOME >> MEDICINE >> NEWS
Smoking affects same 'feel good' brain chemical system as heroin

ng called positron emission tomography, or PET, imaging. This allowed them to literally see activity in the endogenous opioid system when the study participants first smoked a special cigarette with almost no nicotine, and then smoked a regular cigarette. Before, during and after the scans, the participants rated how relaxed, alert, sick and nervous they felt, and how much they were craving tobacco.

The new findings confirm previous animal studies, and add to scientists' previous understanding of how smoking affects the flow of another "feel good" chemical in the brain, called dopamine. Now, the team is studying the interaction of dopamine and opioids in the brains of smokers and non-smokers.

They also hope to look at underlying genetic differences that might explain variations between people in response to nicotine -- and perhaps differences in how easily people become addicted to cigarettes or quit smoking.

"The interaction of tobacco, and especially nicotine, with brain chemistry is a fascinating area that we're just beginning to understand, especially when it comes to correlating neurochemistry with behavior," says study leader Jon-Kar Zubieta, M.D., Ph.D., a U-M psychiatrist and neuroscientist. "Just as with the 'hard' drugs of abuse, such as heroin and cocaine, the phenomena of pleasure, addiction, increased tolerance and craving from tobacco are firmly rooted in neurochemistry."

Adds veteran tobacco researcher and U-M emeritus pharmacology professor Ed Domino, Ph.D., "Nicotine addiction is one of the most destructive forces in human health, and we must increase our comprehension of it in order to defeat it. This study represents a key step toward that goal."

Zubieta's team has spent several years developing and testing a way of using PET imaging to study the endogenous opioid system, and specifically the chemicals called endorphins and enkephalins.

Those are the same chemicals involved in the "runner's high",
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
26-Oct-2004


Page: 1 2 3 4 5

Related medicine news :

1. Smoking hurts wealth as well as health, study suggests
2. Smoking causes cognitive impairment in adolescents
3. Smoking not linked to hearing loss
4. Smoking triggers early onset of pancreatic cancer
5. Smoking cessation can improve survival among patients with severe COPD
6. Smoking increases risk of colon polyps
7. Smoking and the risk of rheumatoid arthritis
8. Smoking increases papillomavirus risk in HIV-infected women
9. Smoking linked to more than 60 percent of overall cancer death burden in black men
10. Smoking linked to accelerated cognitive decline in the elderly
11. Smoking linked to blindness

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), ... of an innovative new design of the shoulder pad. The shoulder pad provides ... while controlling your pain while using cold therapy. By utilizing ice and water that ...
(Date:10/12/2017)... Rockville, Maryland (PRWEB) , ... October 12, 2017 ... ... a magnetic drug delivery system that we intend to develop to enable prevention ... regimens can lead to severe hearing loss, especially in pediatric patients. For cisplatin, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Leading pediatric ... peers in Washington, D.C., for the 49th Congress of the International Society of ... Vice President of the Center for Cancer and Blood Disorders at Children’s ...
(Date:10/12/2017)... ... October 12, 2017 , ... Health Literacy Innovations ... literacy software tool, and the Cancer Patient Education Network (CPEN), an independent professional ... announce a new strategic alliance. , As CPEN’s strategic partner, HLI will ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... the University of California Berkeley, and other leading institutions in announcing the launch ... of institutions to change the way animals are raised for food. , Founding ...
Breaking Medicine News(10 mins):
(Date:9/12/2017)... YORK , Sept. 12, 2017   EcoVadis , the leading ... has published the first annual edition of its Global CSR Risk and ... companies evaluated by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 ... ... Index ...
(Date:9/12/2017)... Sept. 12, 2017  ValGenesis Inc., the global ... is pleased to announce the appointment of Dr. ... its Board of Directors and Chairman of Advisory ... life science companies to manage their entire validation ... paper in this process. Furthermore, ValGenesis VLMS enables ...
(Date:9/9/2017)... , Sept. 8, 2017 Dealmed Medical ... independent supplier of medical equipment, supplies, drugs, vaccines, and ... has entered into an agreement to acquire Vantage Medical ... based in Holtsville, New York . ... in supplying new and emerging medical practices, will operate ...
Breaking Medicine Technology:
Cached News: