Smoking and the risk of rheumatoid arthritis

ed, the increased risk for RA was assessed at 2.8 times.

For current cigarette smokers without the SE gene, the risk factor was comparable--2.4 times. These findings affirm the SE gene and smoking as independently related to the development of rheumatoid factor positive RA. Among current smokers with the SE gene, however, the disease risk increased to 7.5 times. "The interaction was even more pronounced in smoking subjects with double SE genes, whose relative risk of rheumatoid factor positive RA was 15.7 times higher," observes one of the authors Leonid Padyukov, M.D., Ph.D. However, no risk was found for rheumatoid factor negative RA in this study.

Beyond strengthening the case against cigarette smoking as a health hazard, this study has important implications for ongoing research into the factors contributing to RA and other autoimmune diseases. "Our study also emphasizes the need to include data on environmental exposures in genetic analyses of a complex disease," the authors note.


Contact: Sabina Bossi
Swedish Research Council

Page: 1 2

Related medicine news :

1. Smoking hurts wealth as well as health, study suggests
2. Smoking causes cognitive impairment in adolescents
3. Smoking not linked to hearing loss
4. Smoking triggers early onset of pancreatic cancer
5. Smoking cessation can improve survival among patients with severe COPD
6. Smoking increases risk of colon polyps
7. Smoking affects same feel good brain chemical system as heroin
8. Smoking increases papillomavirus risk in HIV-infected women
9. Smoking linked to more than 60 percent of overall cancer death burden in black men
10. Smoking linked to accelerated cognitive decline in the elderly
11. Smoking linked to blindness

Post Your Comments:

(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... ... 2017 , ... First Healthcare Compliance (FHC), an industry leader ... range of technology and learning solutions at the 68th Annual American Healthcare Association ... held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, Nevada. ...
(Date:10/12/2017)... Wis. (PRWEB) , ... October 12, 2017 , ... ... standard products to meet the demand of today’s consumer and regulatory authorities worldwide. ... of probiotic experts and tested to meet the highest standard. , These ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... leader in post-acute health care, have expanded their existing home health joint venture ... , AccentCare has been operating a joint venture home health company with Asante, ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... HMP ... the recipient of a 2017 Folio Magazine Eddie Digital Award for ‘Best B-to-B Healthcare ... City on October 11, 2017. , The annual award competition recognizes editorial and design ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... Oct. 10, 2017  NDS received FDA 510(k) clearance in May ... battery-powered display stand specifically designed for endoscopy environments. An innovative secondary ... a clinical solution to support the improvement of patient outcomes, procedural ... ... ...
(Date:10/4/2017)... to the Centers for Disease Control and Prevention (CDC), influenza vaccination ... is helping communities across Massachusetts , Connecticut ... flu shots through the end of the month. *Some exclusions ... ... shot is by the end of October, according to the Centers for ...
(Date:10/2/2017)... Halo Labs announces the European launch of their new low volume, ... 2017 in Cambridge, U.K on October 4th. ... samples with unprecedented speed and sensitivity while using far less sample ... ... system ...
Breaking Medicine Technology:
Cached News: