Smoking increases papillomavirus risk in HIV-infected women

Women with HIV infection who smoke are more likely than women not infected with HIV to acquire and have prevalent human papillomavirus (HPV) infection, according to a study published in the May 1 issue of The Journal of Infectious Diseases, now available online. Given the clear link between persistent infection with certain HPV types and cervical cancer, the findings may help to explain why women who are smokers or HIV-infected are at risk for this tumor. They also underscore the importance of smoking cessation in women's health.

The study, reported by Howard Minkoff and coworkers at SUNY Downstate and other centers, involved 1,797 HIV-infected and 496 uninfected women whose smoking and HPV status was monitored at six-month intervals from 1994 to 1998. Smoking status was determined in interviews, HPV status by cervicovaginal lavage for HPV DNA testing. Other factors studied included age, T cell subset concentrations, anti-HIV drug regimen use, HIV RNA levels, oral contraceptive use, and sexual activity.

The investigators found that, regardless of smoking status, HIV-infected women were 3.9 times more likely than women not infected with HIV to have HPV infection at the outset of the study. When smoking was factored into the analysis, heightened HPV risk at the outset was seen only in HIV-infected women. HIV-infected women were also 3.13 times more likely to acquire HPV infection during the study, and smoking significantly increased HPV risk in such women. Finally, both HIV-infected subjects and those who smoked were significantly more likely than their uninfected or nonsmoking counterparts to acquire persistent HPV infection (defined as occurring during the study and present at two consecutive visits).

Noting that persistent HPV infections have been shown to increase the risk of cervical cancer, Minkoff and coworkers commented that smoking and HIV infection may each alter the natural history of HPV infection to heighten tumor risk, an

Contact: Jeff Minerd
Infectious Diseases Society of America

Page: 1 2

Related medicine news :

1. Smoking hurts wealth as well as health, study suggests
2. Smoking causes cognitive impairment in adolescents
3. Smoking not linked to hearing loss
4. Smoking triggers early onset of pancreatic cancer
5. Smoking cessation can improve survival among patients with severe COPD
6. Smoking increases risk of colon polyps
7. Smoking affects same feel good brain chemical system as heroin
8. Smoking and the risk of rheumatoid arthritis
9. Smoking linked to more than 60 percent of overall cancer death burden in black men
10. Smoking linked to accelerated cognitive decline in the elderly
11. Smoking linked to blindness

Post Your Comments:
TAG: Smoking increases papillomavirus risk HIV infected women

(Date:10/9/2015)... ... October 09, 2015 , ... ... promotion on Invisalign, the orthodontic system that uses clear, plastic aligners. This alternative ... invisible against the teeth, which allow patients to complete treatment in privacy. Additionally, ...
(Date:10/9/2015)... ... October 09, 2015 , ... The Asthma and Allergy Foundation ... for Disease Control and Prevention (CDC) to improve the knowledge and skills of underserved ... been awarded a project by the CDC and allows AAFA to continue vital efforts ...
(Date:10/9/2015)... ... October 09, 2015 , ... ... welcoming individuals from all walks of life to save money on the high ... of $25 per month per medication, individuals and families can receive their medications ...
(Date:10/9/2015)... ... October 09, 2015 , ... ... oldest and largest recreational dispensaries in Colorado, says the latest figures on the ... rapidly and maturing into a legitimate industry. , Last month, according to ...
(Date:10/9/2015)... ... , ... Smanos was featured on NewsWatch as part of its monthly Tech ... a technology expert and special reporter for NewsWatch, conducted the review and shared with ... this day and age it’s more important than ever to keep homes and dorms ...
Breaking Medicine News(10 mins):
(Date:10/9/2015)... India , October 9, 2015 ... analysis of major players. --> ... players. --> RnRMarketResearch.com announces addition of ... status and 2020 forecasts for global markets as ... India along with analysis of major ...
(Date:10/9/2015)... 2015 Henry Schein , Inc. (NASDAQ: ... care products and services to office-based dental, animal health ... Henry Schein Disaster Relief Hotline is open for dentists, ... issues as a result of the disastrous flooding in ... for all Henry Schein customers is 800-999-9729. ...
(Date:10/9/2015)... , Oct. 9, 2015  Impax Laboratories, Inc. ... will release its third quarter 2015 financial results on ... the U.S. financial markets. The Company will host a ... at 8:30 a.m., Eastern Time on November 9, 2015.  ... . --> The financial results and live ...
Breaking Medicine Technology:
Cached News: