HOME >> MEDICINE >> NEWS
Smoking increases papillomavirus risk in HIV-infected women

Women with HIV infection who smoke are more likely than women not infected with HIV to acquire and have prevalent human papillomavirus (HPV) infection, according to a study published in the May 1 issue of The Journal of Infectious Diseases, now available online. Given the clear link between persistent infection with certain HPV types and cervical cancer, the findings may help to explain why women who are smokers or HIV-infected are at risk for this tumor. They also underscore the importance of smoking cessation in women's health.

The study, reported by Howard Minkoff and coworkers at SUNY Downstate and other centers, involved 1,797 HIV-infected and 496 uninfected women whose smoking and HPV status was monitored at six-month intervals from 1994 to 1998. Smoking status was determined in interviews, HPV status by cervicovaginal lavage for HPV DNA testing. Other factors studied included age, T cell subset concentrations, anti-HIV drug regimen use, HIV RNA levels, oral contraceptive use, and sexual activity.

The investigators found that, regardless of smoking status, HIV-infected women were 3.9 times more likely than women not infected with HIV to have HPV infection at the outset of the study. When smoking was factored into the analysis, heightened HPV risk at the outset was seen only in HIV-infected women. HIV-infected women were also 3.13 times more likely to acquire HPV infection during the study, and smoking significantly increased HPV risk in such women. Finally, both HIV-infected subjects and those who smoked were significantly more likely than their uninfected or nonsmoking counterparts to acquire persistent HPV infection (defined as occurring during the study and present at two consecutive visits).

Noting that persistent HPV infections have been shown to increase the risk of cervical cancer, Minkoff and coworkers commented that smoking and HIV infection may each alter the natural history of HPV infection to heighten tumor risk, an
'"/>

Contact: Jeff Minerd
jminerd@idsociety.org
703-299-0200
Infectious Diseases Society of America
29-Apr-2004


Page: 1 2

Related medicine news :

1. Smoking hurts wealth as well as health, study suggests
2. Smoking causes cognitive impairment in adolescents
3. Smoking not linked to hearing loss
4. Smoking triggers early onset of pancreatic cancer
5. Smoking cessation can improve survival among patients with severe COPD
6. Smoking increases risk of colon polyps
7. Smoking affects same feel good brain chemical system as heroin
8. Smoking and the risk of rheumatoid arthritis
9. Smoking linked to more than 60 percent of overall cancer death burden in black men
10. Smoking linked to accelerated cognitive decline in the elderly
11. Smoking linked to blindness

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/5/2016)... ... , ... Love is in the air at King Kullen! The local grocer ... This staple for Valentine’s Day is a must-have, and can be picked up with ... only are long-stem roses available, but also other flower bouquets, elegantly wrapped and ready ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... of Popeyes Louisiana Kitchen restaurants, launched the 14th annual “Appetite for a Cure” ... adults with muscular dystrophy, ALS and related diseases that severely limit strength and ...
(Date:2/5/2016)... ... February 05, 2016 , ... The ... funding innovative lymphoma research and serving the lymphoma community through a comprehensive series ... again host, Swirl, A Wine Tasting Event at the La Gorce Country Club ...
(Date:2/5/2016)... ... ... Give To Cure today announced that it is working with ... Cure’s campaign that is crowdfunding clinical trials to help find cures faster for Alzheimer’s ... smart device. In 2015 alone, Venmo processed $7.5 billion in transactions among users. , ...
(Date:2/5/2016)... ... February 05, 2016 , ... Stuart Bentkover, MD, ... the PicoSure. Designed to provide the most effective tattoo removal today, Dr. Bentkover is ... results. , Developed by Cynosure, the PicoSure has been approved by the Food and ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... 2016  The Senior Care Pharmacy Coalition (SCPC) ... Chairman Jason Chaffetz (R-UT) and Ranking ... hearing , "Developments in the Prescription Drug Market," ... questions about abusive pharmacy benefit manager (PBM) pricing ... Ranking Member Elijah Cummings (D-MD) are diligent, serious ...
(Date:2/4/2016)... 4, 2016  SciClone Pharmaceuticals, Inc. (NASDAQ: ... entered into a settlement agreement with the United ... the SEC,s investigation into possible violations of the ... of the settlement agreement, SciClone has agreed to ... pre-judgment interest and a penalty.  This payment is ...
(Date:2/4/2016)... , Feb. 4, 2016 Summary Breast ... cancer and the most common cancer in women worldwide, ... disease exceedingly prevalent. The number of women diagnosed with ... but the number of deaths has declined due to ... treatment has been revolutionized in the past four decades, ...
Breaking Medicine Technology:
Cached News: