HOME >> MEDICINE >> NEWS
Spina bifida: 70% of cases preventable by folic-acid supplementation

This release is also available in German.

A seminar in this week's issue of THE LANCET discusses the causes, symptoms, and treatments relating to spina bifida, and reinforces an important public-health message for women about to become pregnant: 70% of cases of spina bifida are preventable by folic-acid supplementation around the time of conception and during early pregnancy.

Spina bifida results from failure of fusion of the neural tube (the embryonic form of the brain and spinal cord), and is one of the most common malformations of human structure. The causes of this disorder are varied, including chromosome abnormalities and gene disorders. The cause is not known in most cases.

Laura Mitchell (The Texas A&M University System Health Science Center, USA) and colleagues highlight how up to 70% of spina bifida cases can be prevented by maternal folic acid supplementation around the time of conception. The mechanism underlying this protective effect is unknown, state the authors, but it is likely to include genes that regulate folate transport and metabolism.

The authors also outline how individuals with spina bifida need both surgical and medical management. Although surgical closure of the malformation is generally done in the neonatal period, a randomised clinical trial to assess in utero closure of spina bifida has been initiated in the USA. Medical management is a lifelong necessity for individuals with spina bifida, and should be provided by a multidisciplinary team.

Dr Mitchell concludes: "Spina bifida is the only birth defect for which there have been tremendous successes in both treatment and prevention. Continuing advances in our understanding of the human genome are providing new opportunities to understand the causes of this disorder, and offer the prospect of developing improved strategies for the prevention of spina bifida. Moreover, in
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
1-212-633-3810
Lancet
18-Nov-2004


Page: 1 2

Related medicine news :

1. Spinal repair pioneer to speak in NY on 20th Jan
2. Spinal cord injury patients show improvement in early device study
3. Spinal disc repair start-up orthonics receives funding from Viscogliosi Brothers, LLC
4. New Technique Induces Growth Across Spinal Cord Injury
5. UK Researchers Receive Grants To Examine Benefits Of Aerobic Exercise For People With Spinal Cord Injuries
6. Cut Nerve Fibers Are Repaired In An Animal Model of Spinal Cord Injury; May Help Repair Nerve Damage In Humans
7. Researchers Splice Severed Spinal Cords
8. Study Shows Calcitonin-Salmon Nasal Spray Helps Prevent New Spinal Fractures In Women With Existing Osteoporosis
9. Novel Therapy Significantly Reduces Spinal Fractures In Postmenopausal WomenWith Two Years Of Therapy
10. New Data Show Evista Reduces Spinal Fractures
11. First UK cases of previously rare disease reported in gay men

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... (PRWEB) , ... September 03, 2020 , ... ... of Approval for Sunrise Technologies WALI wireless parking lot controller. This advanced LED ... minimizing glare, reducing light trespass, and protecting the night sky against light pollution. ...
(Date:9/1/2020)... ... September 01, 2020 , ... KitoTech ... million convertible note financing, which will be used to accelerate the commercialization of ... this financing, the company will continue to expand its customer base of healthcare ...
(Date:9/1/2020)... ... 01, 2020 , ... Dr. Kiran Gill is a Board ... the face, breast, and body. In 2018, she founded Aesthetics in Plastic Surgery ... aesthetic practice in Southwest Florida. Dr. Gill and her team offer surgical and ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... Just found out your dear friend has ... heartbreaking when your friend or family member shares their diagnosis. Once the shock wears off, ... say the wrong thing? What are the best ways to help? Words are failing me. ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... for chiropractors, announced today the launch of its integrated, HIPAA compliant, telehealth solution, ... their virtual practice in under 90 seconds. , According to the U.S. ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... September is National Ovarian Cancer ... more deaths than any other cancer of the female reproductive system. The American ... cancer and about 14,000 women will die from this disease. Throughout the month ...
(Date:8/31/2020)... ... 31, 2020 , ... If you live in New York City you will always pay more ... it’s the law of supply and demand, but are plastic surgeons in New York worth ... of their patients that make the four-hour trip to have expert aesthetic treatments by some ...
(Date:8/31/2020)... ... 2020 , ... Cloudticity announced today that Network Products Guide, ... in the 15th Annual 2020 Network PG’s IT World Awards®. , The IT ... Products Guide honoring achievements of world’s best in organizational performance, product and service ...
Breaking Medicine Technology:
Cached News: