HOME >> MEDICINE >> NEWS
St. John's wort ineffective for depression

DURHAM, N.C. The largest clinical trial performed to date on the popular herbal supplement St. John's wort (Hypericum perforatum) has found it to be no more effective than placebo for the treatment of a moderately severe form of major depression, according to researchers at Duke University Medical Center. Major depression, also called major depressive disorder, is one of the most common forms of depression.

Researchers designed the study to test the efficacy of St. John's wort (SJW) versus placebo for the treatment of major depression. In their study, they used the antidepressant sertraline (trade name Zoloft), which is a selective serotonin reuptake inhibitor (SSRI), as a "control" to measure the sensitivity of the study for detecting antidepressant effects of hypericum. SSRIs such as sertraline are a class of drug found to be effective in treating several forms of depression.

"Major depression is treatable, but this research suggests that major depression of at least moderate severity should not be treated with St. John's wort," said Jonathan R.T. Davidson, M.D., director of the Anxiety and Traumatic Stress Program at Duke and principal investigator of the study. "Rather than self-medicate with an over-the-counter medication or supplement, patients are strongly advised to consult an appropriate healthcare provider to assess the best treatment for a depressive episode."

Another author on the study, Robert Califf, M.D., director of the Duke Clinical Research Institute, emphasized the dangers of inadequate studies of St. John's wort and other herbal remedies.

"As long as these types of products remain available to the public without the protection of adequate, controlled and unbiased studies, taking them is like playing Russian roulette with your health," he said.

Study results appear in the April 10, 2002 issue of the Journal of the American Medical Association. Duke University Medical Center, Duke Clinical Research Institute (DCRI)
'"/>

Contact: Tracey Koepke
koepk002@mc.duke.edu
919-684-4148
Duke University
9-Apr-2002


Page: 1 2 3 4 5

Related medicine news :

1. St. Johns wort amplifies effect of blood thinner Plavix
2. The effects of St. Johns Wort (Hypericum perforatum)
3. UT Southwestern Study To Test Efficacy Of St. Johns Wort For Treatment Of Depression
4. Study Finds St. Johns Wort Can Cut Alcohol Consumption
5. Government wasting your taxpayer money on ineffective drug cure
6. School-based smoking prevention programs ineffective
7. Surgical procedure to treat GERD in children found to be ineffective
8. Fetal heart monitoring ineffective at diagnosing cerebral palsy
9. Doubling of steroid before severe asthma attack ineffective
10. Promising drug proves ineffective as treatment for hearing loss
11. Screening children for speech problems is ineffective

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: John wort ineffective for depression

(Date:2/27/2015)... The Hermitage has responded to a ... that date back to 2012. The mitigation work that ... as it was approved in the summer of 2013. ... allegations we agreed to 100% mitigation at our expense," ... Company. , Barnes further added, "we were surprised and ...
(Date:2/27/2015)... 27, 2015 UAS LifeSciences, will showcase ... Natural Products Expo West, March 6 to 8 in ... to release the hands down best tasting probiotic in ... an extra zing of Vitamin C. This is a ... the NutrAward 2014, Delicious Living’s Supplement Award and Taste ...
(Date:2/27/2015)... 2015 According to the Center ... 38 million children and adolescents participate in sports ... a result of this growing number, new and ... and square footage creating a need for preventative ... , "Athletic facilities are hosting a record ...
(Date:2/27/2015)... GA (PRWEB) February 27, 2015 Leading ... and Consumer Protection, PartnerTech Inc. President, Gary ... Association of Georgia (TAG) for the TechAmerica DC ... leaders on legislation regarding technology along with the opportunity ... manufacturer of technology driven products, evidenced by their current ...
(Date:2/27/2015)... Javon Bea Mercy Health System President and ... open to the public, is held the second Tuesday ... Food Court, 2500 Milton Ave. Monthly meetings include a ... an educational health-related presentation. Participants receive a free t-shirt ... Health. , March 10: Using exercise to feel better ...
Breaking Medicine News(10 mins):Health News:Southern Vermont's Hermitage Club Announces Statement Regarding Vermont Attorney General Lawsuit for Permit Violations 2Health News:UAS LifeSciences to Launch UP4 Adult Cubes at Expo West 2Health News:Rise of Students Participating in Sports Creates Need for Preventative Maintenance to Gymnasium Equipment in Athletic Facilities 2Health News:Rise of Students Participating in Sports Creates Need for Preventative Maintenance to Gymnasium Equipment in Athletic Facilities 3Health News:PartnerTech Joins Technology Association of Georgia for TechAmerica DC Fly-In 2Health News:PartnerTech Joins Technology Association of Georgia for TechAmerica DC Fly-In 3
(Date:2/26/2015)... , February 26, 2015 ... (Filter, Bottle washer, Filler, Capper, Blow molder, Shrink ... Application (Still, Flavored, Sparkling) & Region - Trends ... and segments the bottled water processing market with ... in terms of value. It also identifies the ...
(Date:2/26/2015)... Feb. 26, 2015 People with psoriasis ... opportunity to participate in research that aims to ... independent U.S. psoriasis registry begins recruiting patients in ... with the National Psoriasis Foundation and Corrona, LLC, ... secukinumab, a new biologic medication by Novartis Pharmaceuticals ...
(Date:2/26/2015)... 2015  MEI Pharma, Inc. (Nasdaq: MEIP ), ... therapies for cancer, announced today that Daniel P. Gold ... the Cowen and Company 35 th Annual Health Care ... time from the Boston Marriott Copley Place. A live webcast ... A replay will be available approximately one hour after the ...
Breaking Medicine Technology:Bottled Water Processing Market Worth $2,106.5 Million by 2019 2Bottled Water Processing Market Worth $2,106.5 Million by 2019 3Bottled Water Processing Market Worth $2,106.5 Million by 2019 4First independent U.S. psoriasis registry will track drug safety and effectiveness 2First independent U.S. psoriasis registry will track drug safety and effectiveness 3MEI Pharma to Present at Cowen and Company Health Care Conference 2MEI Pharma to Present at Cowen and Company Health Care Conference 3
Cached News: