HOME >> MEDICINE >> NEWS
St. John's wort ineffective for depression

DURHAM, N.C. The largest clinical trial performed to date on the popular herbal supplement St. John's wort (Hypericum perforatum) has found it to be no more effective than placebo for the treatment of a moderately severe form of major depression, according to researchers at Duke University Medical Center. Major depression, also called major depressive disorder, is one of the most common forms of depression.

Researchers designed the study to test the efficacy of St. John's wort (SJW) versus placebo for the treatment of major depression. In their study, they used the antidepressant sertraline (trade name Zoloft), which is a selective serotonin reuptake inhibitor (SSRI), as a "control" to measure the sensitivity of the study for detecting antidepressant effects of hypericum. SSRIs such as sertraline are a class of drug found to be effective in treating several forms of depression.

"Major depression is treatable, but this research suggests that major depression of at least moderate severity should not be treated with St. John's wort," said Jonathan R.T. Davidson, M.D., director of the Anxiety and Traumatic Stress Program at Duke and principal investigator of the study. "Rather than self-medicate with an over-the-counter medication or supplement, patients are strongly advised to consult an appropriate healthcare provider to assess the best treatment for a depressive episode."

Another author on the study, Robert Califf, M.D., director of the Duke Clinical Research Institute, emphasized the dangers of inadequate studies of St. John's wort and other herbal remedies.

"As long as these types of products remain available to the public without the protection of adequate, controlled and unbiased studies, taking them is like playing Russian roulette with your health," he said.

Study results appear in the April 10, 2002 issue of the Journal of the American Medical Association. Duke University Medical Center, Duke Clinical Research Institute (DCRI)
'"/>

Contact: Tracey Koepke
koepk002@mc.duke.edu
919-684-4148
Duke University
9-Apr-2002


Page: 1 2 3 4 5

Related medicine news :

1. St. Johns wort amplifies effect of blood thinner Plavix
2. The effects of St. Johns Wort (Hypericum perforatum)
3. UT Southwestern Study To Test Efficacy Of St. Johns Wort For Treatment Of Depression
4. Study Finds St. Johns Wort Can Cut Alcohol Consumption
5. Government wasting your taxpayer money on ineffective drug cure
6. School-based smoking prevention programs ineffective
7. Surgical procedure to treat GERD in children found to be ineffective
8. Fetal heart monitoring ineffective at diagnosing cerebral palsy
9. Doubling of steroid before severe asthma attack ineffective
10. Promising drug proves ineffective as treatment for hearing loss
11. Screening children for speech problems is ineffective

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/26/2016)... ... 26, 2016 , ... OncLive® , a leading digital ... University of Virginia (UVA) Cancer Center to its quickly expanding ... teams will publicize and promote public awareness of UVA Cancer Center’s latest advances ...
(Date:5/26/2016)... ... May 26, 2016 , ... A health conscious snack that doesn't ... Bar, has ignited an undeniable buzz in the protein product community by offering ... any doughnut.  These doughnuts are packed with 11 grams of protein and made from ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... provide strategic sales leadership and to further develop their rapidly expanding portfolio of ... Business Administration with a concentration in Marketing and an M.B.A. with concentration in ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... enhance surgical safety efforts for several years, and the efforts have paid off. ... These efforts include new standards of care to enhance perioperative patient experiences and ...
(Date:5/26/2016)... ... 26, 2016 , ... Dr. LeRoy Perry’s recently authored whitepaper, “Tech Neck and ... the billions of users, hundreds of millions of whom are coming into the workplace ... frequent and common action of looking down at hand-held technology devices (tablets, smartphones) for ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... -- Cirujanos holandeses han puesto en marcha ... a compartir sus mejores prácticas por el mundo y ... de Europa, África, Asia y ... que combina la transmisión en vivo con mensajería instantánea ... Educación   "Imagine un médico de Medicines sans ...
(Date:5/24/2016)... Nev. , May 24, 2016  Diana Russell ... "eats" her organs from the inside out.  This disease ... completely dependent on her children and grandchildren to leave ... her wheelchair, Diana,s family cannot haul the wheelchair.  So ... in the car, and Diana is left to wait ...
(Date:5/24/2016)... May 24, 2016 Celsion Corporation (NASDAQ: ... company, today provided an update on its ongoing ... trial combining GEN-1, the Company,s DNA-based immunotherapy, with ... newly-diagnosed patients with advanced ovarian cancer who will ... GEN-1 is an IL-12 DNA plasmid vector formulated ...
Breaking Medicine Technology:
Cached News: