HOME >> MEDICINE >> NEWS
St. Jude leukemia therapy overcomes differences in treatment outcome between black, white children

(MEMPHIS, TENN.--October 14, 2003) Investigators at St. Jude Children's Research Hospital have found that black children are equally likely as white children to benefit from improved treatment for acute lymphoblastic leukemia (ALL), if given equal access to the most advanced therapies.

This finding--that black and white children had virtually equal rates of survival over 10 years--contrasts with the results of clinical studies from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG). The POG and CCG multi-center studies showed that black children lagged behind white children in the cure rate for ALL.

Even though black children referred to St. Jude were more likely to have high-risk leukemia and be socioeconomically underprivileged, they enjoyed the same excellent treatment results as white children, according to Ching-Hon Pui, M.D., director of the St. Jude Leukemia/Lymphoma division.

Pui is senior author of this study, which appears in the Oct. 15 issue of the Journal of the American Medical Association. Despite black children presenting with more bulky disease at diagnosis and having unfavorable genetic subtypes of leukemia, the St. Jude treatment was able to achieve high cure rates that were equal in black and white children.

"It's remarkable that, although African-American children with ALL are more likely than white children to have high-risk leukemia, the black children in our studies derived as much benefit from therapy as white children," said William Evans, Pharm.D., St. Jude scientific director and a co-author of the study. "This is apparently due to the modifications we made to our previous, very successful therapies for ALL, making those treatments even more effective."

One factor contributing to the treatment success rate among black children is that all St. Jude patients received a personally tailored approached to treatment--called risk-directed therapy--regardless of health insurance s
'"/>

Contact: Bonnie Cameron
bonnie.cameron@stjude.org
901-495-4815
St. Jude Children's Research Hospital
14-Oct-2003


Page: 1 2

Related medicine news :

1. Both inherited traits and tumor mutations affect response to treatment of leukemia
2. Plant derivative attacks the roots of leukemia
3. Protein that promotes survival of stem cells might be key to poor leukemia prognosis
4. Study finds new designer drug is potent treatment for chronic myelogenous leukemia
5. Study finds new designer drug is potent treatment for chronic myelogenous leukemia
6. New leukemia drug shows promise in overriding all Gleevec resistance
7. Cord blood transplantation now a viable option for adult leukemia patients
8. Peptide vaccine can produce complete remission in myeloid leukemia patients
9. Methylphenidate improves attention, behavior of children surviving leukemia, brain tumors
10. Obesity linked to another cancer - leukemia in older women
11. Improved acute lymphoblastic leukemia treatment offers hope for eliminating irradiation

Post Your Comments:
(Date:7/31/2014)... Dublin, Ohio (PRWEB) July 31, 2014 ... solutions for health care, announces the release of a “Twelve ... web seminar for hospitals that are evaluating Health Information Service ... 2. Hospitals that utilize MEDITECH and Epic electronic health ... order to exchange transitions of care using the Direct protocol. ...
(Date:7/31/2014)... 2014 A cancer diagnosis is crushing and ... and resume normal lives. This is particularly true of prostate ... one in seven American men but which when detected early, ... rate of nearly 100% and a ten-year survival rate of ... diagnosed with the disease do not die from it. There ...
(Date:7/31/2014)... its latest blog post, Best Drug Rehabilitation , which ... during a stay in rehab can make a big difference ... on nine secrets that addicts don’t want others to know. ... an addict from a mile away, and totally understand what’s ... Per Wickstrom . “However, take it from me: spotting ...
(Date:7/31/2014)... July 31, 2014 In its latest blog ... and believes that having family close by during a stay ... not the process is successful, is looking at 10 tips ... , “Addiction recovery is a lifelong process, and one ... be committed to without compromise,” commented Best Drug Rehabilitation’s CEO ...
(Date:7/31/2014)... Oregon (PRWEB) July 31, 2014 ... properties and digestibility, erythritol has long been used ... such as stevia and monk fruit. However consistent, ... In an effort to meet food and beverage ... sourcing, Steviva Ingredients has launched GMO-free ErysweetTM Erythritol. ...
Breaking Medicine News(10 mins):Health News:Updox Introduces Resources to Help Hospitals Choose the Right HISP for Direct Messaging 2Health News:Updox Introduces Resources to Help Hospitals Choose the Right HISP for Direct Messaging 3Health News:Updox Introduces Resources to Help Hospitals Choose the Right HISP for Direct Messaging 4Health News:Restoring Intimacy after Prostate Cancer; Dr. Daniel Watter with Morris Psychological Group Offers Tips for Patients and their Partners 2Health News:Restoring Intimacy after Prostate Cancer; Dr. Daniel Watter with Morris Psychological Group Offers Tips for Patients and their Partners 3Health News:Restoring Intimacy after Prostate Cancer; Dr. Daniel Watter with Morris Psychological Group Offers Tips for Patients and their Partners 4Health News:Latest Best Drug Rehabilitation Blog Posts Focuses on Nine Secrets Addicts Don’t Want Others to Know 2Health News:Latest Best Drug Rehabilitation Blog Posts Focuses on Nine Secrets Addicts Don’t Want Others to Know 3Health News:New Best Drug Rehabilitation Blog Posts Looks at 10 Tips for Coping After Drug or Alcohol Rehab 2Health News:Steviva Ingredients Launches Erysweet Erythritol 2
(Date:7/30/2014)... Calif. , July 30, 2014  El Camino ... improve patient care, is utilizing the Leaf Patient Monitoring ... the position and movement of patients susceptible to bed ... a six month-long, 138-patient study of the system, which ... turn protocols. Turning patients regularly is the one of ...
(Date:7/30/2014)... July 30, 2014  InnoPharma, Inc. today announced the ... generic equivalent of Zyprexa® injection), in Canada.  Olanzapine is ... behaviors in patients with schizophrenia or bipolar I mania. ... drug, InnoPharma has entered into an agreement with Sandoz ... will make, use, sell, market and distribute Olanzapine Injection ...
(Date:7/30/2014)... July 30, 2014 Cynosure, Inc. (NASDAQ: ... aesthetic treatments for non-invasive and minimally invasive applications, today announced ... Chief Operating Officer and Chief Financial Officer Timothy W. ... 2014.  Baker, 53, will continue to serve as CFO and ... , who remains Chairman and Chief Executive Officer. ...
Breaking Medicine Technology:El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 2El Camino Hospital Utilizes Cutting-Edge Leaf Patient Monitor System to Help Reduce Risk of Pressure Ulcers 3InnoPharma Announces Launch of Olanzapine for Injection, 10mg/vial in Canada 2Cynosure Appoints Chief Operating Officer and Chief Financial Officer Timothy W. Baker as President 2
Cached News: