Standard treatment for rare form of deafness no more effective than placebo

assigned to take either methotrexate or an inactive pill made from sugar or starch, known as a placebo.

Espeland said the study is important because it could prevent people with AIED from getting a treatment that doesn't work. It also alerts researchers to focus attention on potential treatments for the disease.

"The results of this study clearly underscore the need for more effective and less toxic therapy for AIED, and that randomized, controlled trials are necessary to establish benefit," wrote the researchers in JAMA.

Wake Forest was the national coordinating center for the study, which was led by Dr. Jeffrey P. Harris, M.D., Ph.D., at the University of California in San Diego.


Contact: Karen Richardson
Wake Forest University Baptist Medical Center

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