Stanford researcher to find cure for widespread Celi...( st prevalent substances in foods medic...),Health

st prevalent substances in foods, medicines and other consumer products, yet for approximately 1 in 200 individuals around the world who are Celiacs, even an occasional encounter with gluten may make them ill. And the long-term implications of the untreated disease, which include a substantially enhanced risk of malignancies (both cancer and lymphoma) of the small intestine and osteoporosis, are far more serious than the disease itself.

"It is now important to begin the process of translating new scientific knowledge about Celiac Sprue into products and technologies that will help patients," Dr. Gray continued. Dr. Gray co-chairs the Scientific Advisory Board forth Celiac Sprue Research Foundation.

Notwithstanding the need for a Celiac pill to cure the disease, this problem has escaped the attention of the pharmaceutical industry thus far. "This is a bold experiment in which a non-profit organization, rather than a pharmaceutical company, is taking the lead in drug development for a major unmet medical need," said Christopher T. Walsh, a Professor at Harvard Medical School and a former President of the Dana Farber Cancer Center in Boston. Dr. Walsh serves on the Board of Directors of the Celiac Sprue Research Foundation, and is also an advisor to several pharmaceutical and biotechnology companies. He continued that, if successful, "The Foundation could not only help Celiacs, but also set an example for how other overlooked diseases could be attacked."

What is Celiac Sprue?

Celiac Sprue (a.k.a. celiac disease, coeliac disease, or gluten intolerance) is an hereditary disorder characterized by a sensitivity to the toxic effects of gluten in the diet, leading to abnormal small-intestinal structure, malabsorption, and intolerance to gluten, a component of nutritionally important proteins found in common dietary food grains such as wheat, rye and barley.

The disease commonly presents in early childhood with severe sy
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Contact: Chaitan Khosla
csrf@celiacsprue.org
650-251-9865
Celiac Sprue Research Foundation
26-Sep-2002

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