Starting dose of Lexapro as effective as optimally dosed Zoloft in the treatment of depression

NEW YORK, December 10 Forest Laboratories, Inc. (NYSE: FRX) announced today the results of a clinical study, which showed that LexaproTM (escitalopram oxalate) is as effective and well tolerated as Zoloft (sertraline hydrochloride). The purpose of the study was to evaluate whether the starting dose of Lexapro, 10 mg per day, could provide comparable efficacy to the full dosing range of Zoloft, 50 200 mg per day. Study results showed that patients receiving a dose of 10 mg per day of Lexapro experienced similar efficacy compared to patients receiving a median dose of Zoloft of 150 mg per day. At week four, 46 percent of Zoloft-treated patients received 150 mg per day or higher, and at week eight, 65 percent received 150 mg per day or higher. To achieve a dose of 150 mg per day or higher, patients treated with Zoloft required at least two dose titrations. Both Lexapro and Zoloft belong to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). The study was presented in Puerto Rico at an annual meeting of neuropsychopharmacologists.

"In this study, most patients experienced relief from depressive symptoms. Patients treated with Lexapro received 10 mg throughout the study period, while patients treated with Zoloft received dosages based on depressive symptoms and the development of side effects," said George Alexopoulos, M.D., Professor of Psychiatry at Weill Medical College of Cornell University. "Lexapro is an effective treatment for depression with simple dosing that may improve patient adherence."

Each year, nearly 19 million adult Americans suffer from mild, moderate, or severe depression. One in 4 women and 1 in 10 men can expect to be diagnosed with depression during their lifetime. Depression costs the United States an estimated $44 billion each year. The World Health Organization predicts depression will become the leading cause of disability by the year 2020.

Study Conclusions<

Contact: Charles E. Triano
Forest Laboratories

Page: 1 2 3

Related medicine news :

1. Starting beta-blocker before discharge in patients hospitalized for heart failure increases usage
2. Lexapro receives FDA approval for the treatment of generalized anxiety disorder
3. Strategy effective against drug resistant tuberculosis
4. Study shows patch therapy may be as effective as oral medications
5. Chronic pain treatments more effective when taken together, new study shows
6. Geodon effective in psychiatric emergencies; Sharply reduces time in restraints
7. Costs of antidepressants could have funded effective alternatives
8. New ways to design safer & more effective topical (transdermal) drug delivery announced in the PNAS
9. Government wasting your taxpayer money on ineffective drug cure
10. Neurobehavioral function during coma, stroke rehabilitation effective for elderly
11. European folic acid policies are not effective enough

Post Your Comments:

(Date:11/27/2015)... ... , ... According to an article published November 13th on DrBicuspid.com, ... D.C. revolved around the fact that proper dental care, both at-home and in the ... between periodontal disease (more commonly referred to as gum disease) and diabetes. According to ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... affecting the health care in America. As people age, more care is needed, ... costs are rising, and medical professionals are being overworked. The forgotten part of ...
(Date:11/27/2015)... ... November 27, 2015 , ... "When I was traveling, ... from Hillside, N.J. "Many people catch diseases simply from sitting on such dirty ... be protected from germs." , He developed the patent-pending QUDRATECS to eliminate the ...
(Date:11/27/2015)... ... 2015 , ... ProSidebar: Fashion is a set of 30 kinetic ... Fasion, video editors can easily add an informative sidebar to any FCPX production. ... presets featuring self-animating drop zones, lines, bars, and text with the ease of FCPX's ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s official ... independent group of Microsoft Dynamics SL software users, partners, industry experts and representatives. ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 Research and Markets ( http://www.researchandmarkets.com/research/lttqph/asia_pacific ) ... Pacemaker Market Outlook to 2019 - Rise in Cardiac Disorders ... report to their offering. Boston ... Boston scientific and others. --> ... Biotronik, Boston scientific and others. ...
(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 ... the addition of the "2016 Future Horizons ... Monitoring (TDM) Market: Supplier Shares, Country Segment Forecasts, ... offering. --> ... comprehensive analysis of the Japanese therapeutic drug monitoring ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Testing Market: Supplier Shares, Competitive ... offering.  --> http://www.researchandmarkets.com/research/4gmqdf/2016_future ) ... "2016 Future Horizons and Growth Strategies ...
Breaking Medicine Technology:
Cached News: