HOME >> MEDICINE >> NEWS
Starting dose of Lexapro as effective as optimally dosed Zoloft in the treatment of depression

NEW YORK, December 10 Forest Laboratories, Inc. (NYSE: FRX) announced today the results of a clinical study, which showed that LexaproTM (escitalopram oxalate) is as effective and well tolerated as Zoloft (sertraline hydrochloride). The purpose of the study was to evaluate whether the starting dose of Lexapro, 10 mg per day, could provide comparable efficacy to the full dosing range of Zoloft, 50 200 mg per day. Study results showed that patients receiving a dose of 10 mg per day of Lexapro experienced similar efficacy compared to patients receiving a median dose of Zoloft of 150 mg per day. At week four, 46 percent of Zoloft-treated patients received 150 mg per day or higher, and at week eight, 65 percent received 150 mg per day or higher. To achieve a dose of 150 mg per day or higher, patients treated with Zoloft required at least two dose titrations. Both Lexapro and Zoloft belong to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). The study was presented in Puerto Rico at an annual meeting of neuropsychopharmacologists.

"In this study, most patients experienced relief from depressive symptoms. Patients treated with Lexapro received 10 mg throughout the study period, while patients treated with Zoloft received dosages based on depressive symptoms and the development of side effects," said George Alexopoulos, M.D., Professor of Psychiatry at Weill Medical College of Cornell University. "Lexapro is an effective treatment for depression with simple dosing that may improve patient adherence."

Each year, nearly 19 million adult Americans suffer from mild, moderate, or severe depression. One in 4 women and 1 in 10 men can expect to be diagnosed with depression during their lifetime. Depression costs the United States an estimated $44 billion each year. The World Health Organization predicts depression will become the leading cause of disability by the year 2020.

Study Conclusions<
'"/>

Contact: Charles E. Triano
212-224-6714
Forest Laboratories
10-Dec-2003


Page: 1 2 3

Related medicine news :

1. Starting beta-blocker before discharge in patients hospitalized for heart failure increases usage
2. Lexapro receives FDA approval for the treatment of generalized anxiety disorder
3. Strategy effective against drug resistant tuberculosis
4. Study shows patch therapy may be as effective as oral medications
5. Chronic pain treatments more effective when taken together, new study shows
6. Geodon effective in psychiatric emergencies; Sharply reduces time in restraints
7. Costs of antidepressants could have funded effective alternatives
8. New ways to design safer & more effective topical (transdermal) drug delivery announced in the PNAS
9. Government wasting your taxpayer money on ineffective drug cure
10. Neurobehavioral function during coma, stroke rehabilitation effective for elderly
11. European folic acid policies are not effective enough

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/22/2017)... (PRWEB) , ... February 22, 2017 , ... Pet obesity ... and 54% of dogs, according to the Association for Pet Obesity Prevention (APOP). During ... key pet food issues such as the benefits of corn and grains, value of ...
(Date:2/22/2017)... ... 22, 2017 , ... FPS is a nonprofit mental health ... in 1977, our organization was at the forefront in working with veterans with ... were evident and served as the catalyst for the establishing the agency. , ...
(Date:2/22/2017)... ... February 22, 2017 , ... In today’s world, ... solutions on the market, it is easy to start feeling frustrated and confused. ... offers a complimentary security consultation. , Home Security Hardware Choices, There are innumerable ...
(Date:2/22/2017)... ... February 22, 2017 , ... Alto-Shaam is pleased to announce ... Oven offers up to four ovens in one. Control temperature, fan speed and ... evenness in cooking. Alto-Shaam has partnered with Appliance Innovation to introduce this game-changing ...
(Date:2/22/2017)... CALIFORNIA (PRWEB) , ... February 22, 2017 , ... ... the pipeline and the number of African American/Black students who want to become ... residents to pursue their careers as physicians in the Oakland/San Francisco Northern California, ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... , Feb. 22, 2017   Protein Sciences ... of Flublok® Influenza Vaccine , announced today that ... for Influenza Vaccine Introduction (PIVI) and the Mongolian Ministry ... impacts of the flu.  The doses of Flublok have ... Mongolia for health care workers, pregnant ...
(Date:2/22/2017)... A research report by Arcview Market Research focused on ... continuously changing landscape of the legal market reveals that regulated cannabis ... America , a 30% increase from 2015. According to the ... year 2021 representing a 26 percent compound annual growth rate. The ... and Canada is gradually becoming more mainstream ...
(Date:2/22/2017)...  Tri-Source Pharma announced today the completion of its ... appointed positions were added to form an executive team ... , in the implementation and administration of its newly ... consolidated subsidiary companies. Effective as ... of the following eight members reporting to Robert ...
Breaking Medicine Technology:
Cached News: