HOME >> MEDICINE >> NEWS
Statin drugs may help patients with heart valve disease avoid surgery

ROCHESTER, Minn. -- A study by Mayo Clinic researchers indicates that narrowing of the heart's "exit valve" is less than half as likely to worsen in patients taking statin drugs, as compared with similar patients not taking the cholesterol-lowering medications. The findings, which could lead to the first nonsurgical treatment for aortic stenosis, are reported in the Nov. 20, 2002, issue of the Journal of the American College of Cardiology.

The aortic valve is the one-way gate between the heart's main pumping chamber and the rest of the body. In aortic stenosis, this valve becomes narrowed and causes the heart to work harder. The only treatment for severe aortic stenosis is surgical replacement of the valve.

A new understanding of the aortic stenosis disease process led to the statin study. "In the past few years there has been a total change in our way of thinking, because we realized that what was happening on the aortic valve was a phenomenon similar to atherosclerosis," says Maurice Sarano, M.D., the Mayo Clinic cardiologist who led the study. "Since the disease process is similar to what happens when plaques cause blockages in arteries, reducing the risk factors that lead to heart attack may also help keep the valve from narrowing."

Dr. Sarano and his colleagues screened all adults with aortic stenosis in Olmsted County, Minn. They measured the extent of aortic stenosis using ultrasound and then followed 156 patients for an average of 3.7 years. Because of the close association between high cholesterol and atherosclerosis, the researchers first looked for a link between cholesterol levels and worsening of aortic stenosis. "We were initially somewhat disappointed, because we saw absolutely no association," says Dr. Sarano.

However, when they compared changes in aortic stenosis measurements between the 38 patients who were taking cholesterol-lowering statin drugs and the 118 patients who were not on statin therapy, the statin-th
'"/>

Contact: Lee Aase
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
19-Nov-2002


Page: 1 2

Related medicine news :

1. Statins effective in long term, Nordic study suggests
2. Statins show early promise for treating multiple sclerosis
3. Statins and aspirin may protect against severe vision loss in elderly
4. Statins could reduce stroke risk by a third
5. Statin drugs lower heart disease risk in postmenopausal women
6. Statin drugs may increase risk of peripheral neuropathy
7. Statin drugs may lower risk of Alzheimers
8. Statins may inhibit calcium growth on aortic valve in the elderly
9. People Who Are Diabetic And Glucose Intolerant Can Benefit From "Statin" Drug Therapy, Even If Cholesterol Levels Are Normal
10. International Study Finds Statins Raise Good Cholesterol, Wake Forest Physician Reports
11. Studies Look At Threshold Effect Of Cholesterol-Lowering "Statin" Drugs

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: