Statins could reduce stroke risk by a third

Statins-drugs that lower LDL cholesterol-substantially reduce the incidence of ischaemic stroke among high-risk individuals, conclude authors of a study in this weeks issue of THE LANCET.

Cholesterol lowering with statins is of known benefit for people at increased risk of heart attack. However, current treatment guidelines do not recommend that doctors take account of a person's risk of stroke when deciding whether to use statin therapy. Rory Collins from the Clinical Trial Service Unit, Oxford, UK, and colleagues report detailed results from a five-year study of the effect of simvastatin or placebo among 20,536 people with either a history of stroke or other cerebrovascular disease (3280 people) or at high risk of stroke for other reasons (17,256 people).

Participants were randomly assigned 40 mg simvastatin daily or matching placebo for five years, which yielded an average reduction in LDL cholesterol of 1 mmol/litre. There was a very definite 25% proportional reduction in the incidence of stroke among patients in the simvastatin group (444 strokes; 4.3%) compared with those in the placebo group (585 strokes; 5.7%). This reflected a 30% proportional reduction in the incidence of 'ischaemic' strokes (ie, due to artery blockage in the brain), with no apparent difference in the incidence of 'haemorrhagic' strokes (ie, due to bleeding into the brain). Although the stroke rate was not significantly reduced by simvastatin among participants with a history of cerebrovascular disease, there was a substantial reduction in the combined risk of all major vascular events (ie, heart attacks, strokes, and revascularisation procedures) among these patients.

Rory Collins comments: "This study shows that statin therapy rapidly reduces the incidence not only of heart attacks but also of ischaemic strokes, with no adverse effect on haemorrhagic strokes, even among individuals who do not have high cholesterol concentrations. Allocation to 40 mg simvast

Contact: Joe Santangelo

Page: 1 2

Related medicine news :

1. Statins effective in long term, Nordic study suggests
2. Statins show early promise for treating multiple sclerosis
3. Statins and aspirin may protect against severe vision loss in elderly
4. Statins may inhibit calcium growth on aortic valve in the elderly
5. International Study Finds Statins Raise Good Cholesterol, Wake Forest Physician Reports
6. Charcoal and forest management could reduce greenhouse gas levels & save lives in Africa
7. Novel therapy tested in mice could chase away cat allergies
8. Costs of antidepressants could have funded effective alternatives
9. Emergency clopidogrel could save thousands of lives46,000-patient heart attack trial results
10. Blood pressure treatment could cut risk of strokes and heart attacks
11. Proteins found in urine of pregnant women could help diagnose preeclampsia

Post Your Comments:

(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... June ... about the dangers associated with chronic pain and the benefits of holistic treatments, ... individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is ...
(Date:6/24/2016)... ... 2016 , ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida ... their peers for this recognition are considered among the top 2 percent of lawyers ... as members of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark ...
(Date:6/24/2016)... ... , ... Topical BioMedics, Inc, makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business ... to $12 an hour by 2020 and then adjusting it yearly to increase at the ... minimum wage, assure the wage floor does not erode again, and make future increases more ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... proud to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and ... women in the world, and the most handsome men, look naturally attractive. Plastic ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... National recruitment ... a life sciences executive with extensive sequencing and genomics experience, as Vice President of ... position, Ms. Hill will be responsible for leading the sales team in the commercialization ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
(Date:6/23/2016)... 23, 2016 Any dentist who has made an ... current process. Many of them do not even offer this ... and high laboratory costs involved. And those who ARE able ... such a high cost that the majority of today,s patients ... Parsa Zadeh , founder of Dental Evolutions Inc. and ...
(Date:6/23/2016)... , June 23, 2016 Research and ... Devices Medical Market Analysis 2016 - Forecast to 2022" ... The report contains up to date financial data derived ... Assessment of major trends with potential impact on the market ... of market segmentation which comprises of sub markets, regional and ...
Breaking Medicine Technology:
Cached News: