HOME >> MEDICINE >> NEWS
Statins could reduce stroke risk by a third

Statins-drugs that lower LDL cholesterol-substantially reduce the incidence of ischaemic stroke among high-risk individuals, conclude authors of a study in this weeks issue of THE LANCET.

Cholesterol lowering with statins is of known benefit for people at increased risk of heart attack. However, current treatment guidelines do not recommend that doctors take account of a person's risk of stroke when deciding whether to use statin therapy. Rory Collins from the Clinical Trial Service Unit, Oxford, UK, and colleagues report detailed results from a five-year study of the effect of simvastatin or placebo among 20,536 people with either a history of stroke or other cerebrovascular disease (3280 people) or at high risk of stroke for other reasons (17,256 people).

Participants were randomly assigned 40 mg simvastatin daily or matching placebo for five years, which yielded an average reduction in LDL cholesterol of 1 mmol/litre. There was a very definite 25% proportional reduction in the incidence of stroke among patients in the simvastatin group (444 strokes; 4.3%) compared with those in the placebo group (585 strokes; 5.7%). This reflected a 30% proportional reduction in the incidence of 'ischaemic' strokes (ie, due to artery blockage in the brain), with no apparent difference in the incidence of 'haemorrhagic' strokes (ie, due to bleeding into the brain). Although the stroke rate was not significantly reduced by simvastatin among participants with a history of cerebrovascular disease, there was a substantial reduction in the combined risk of all major vascular events (ie, heart attacks, strokes, and revascularisation procedures) among these patients.

Rory Collins comments: "This study shows that statin therapy rapidly reduces the incidence not only of heart attacks but also of ischaemic strokes, with no adverse effect on haemorrhagic strokes, even among individuals who do not have high cholesterol concentrations. Allocation to 40 mg simvast
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
4-Mar-2004


Page: 1 2

Related medicine news :

1. Statins effective in long term, Nordic study suggests
2. Statins show early promise for treating multiple sclerosis
3. Statins and aspirin may protect against severe vision loss in elderly
4. Statins may inhibit calcium growth on aortic valve in the elderly
5. International Study Finds Statins Raise Good Cholesterol, Wake Forest Physician Reports
6. Charcoal and forest management could reduce greenhouse gas levels & save lives in Africa
7. Novel therapy tested in mice could chase away cat allergies
8. Costs of antidepressants could have funded effective alternatives
9. Emergency clopidogrel could save thousands of lives46,000-patient heart attack trial results
10. Blood pressure treatment could cut risk of strokes and heart attacks
11. Proteins found in urine of pregnant women could help diagnose preeclampsia

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/29/2016)... , ... April 29, 2016 , ... ... loans more flexibility in repaying their loans, more information about their loan terms ... when total outstanding student loan debt, including federal and private loans, has reached ...
(Date:4/29/2016)... Petersburg, Fla. (PRWEB) , ... April 29, 2016 ... ... Children’s Hospital surgeon reveals that infants born with severe congenital diaphragmatic hernia have ... babies is born with congenital diaphragmatic hernia (CDH)—a condition where the diaphragm fails ...
(Date:4/29/2016)... Kansas City, Missouri (PRWEB) , ... April 29, 2016 , ... ... Unlike traditional crutches which put pressure on the armpits, the M+D Crutch evenly distributes ... less strain on their wrists and hands when using the crutches than with other ...
(Date:4/29/2016)... ... ... the deadliest type of skin cancer. Although only about 1 percent of skin cancer cases ... 10,000 people are expected to die of melanoma this year. The risk increases with age, ... most commonly diagnosed cancers in young women. A recent breakthrough in genetic studies may give ...
(Date:4/29/2016)... Hills, CA (PRWEB) , ... April 29, 2016 , ... ... of devices and products for the head and neck/ear, nose and throat specialty, has ... Device , The KOTLER NASAL AIRWAY™ is a newly patented safety device ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... 2016  While Abbott,s announced purchase of St. ... repair and stent business, healthcare research firm Kalorama ... firmly into patient monitoring.  Kalorama said that patient ... areas, with double-digit growth expected the next 5 ... Remote Patient Monitoring . Abbott Laboratories agreed ...
(Date:4/28/2016)... 2016 Treato , the ... announced today that it has been named a Cool ... in Life Sciences, 2016, Stephen Davies , ... focuses on life-science- oriented analytics, algorithms and smart machine ... doctors, confirm medication ingestion, and analyze unstructured information.   ...
(Date:4/28/2016)... 2016  ValGenesis, Inc., the market leader ... today announced that a prominent world provider ... chronic kidney failure has selected ValGenesis Validation ... validation process. The global medical device manufacturer ... manage their validation processes electronically. Upon completion ...
Breaking Medicine Technology:
Cached News: