HOME >> MEDICINE >> NEWS
Statins show early promise for treating multiple sclerosis

Results of a preliminary study in this week's issue of THE LANCET suggest that statins (cholesterol-lowering drugs) could have potential in the treatment of multiple sclerosis (MS).

Drug treatments for MS are expensive and only partially effective. Recent knowledge that statins promote an anti-inflammatory response from the immune system suggest a potential in the treatment of MS.

Inderjit Singh from the Medical University of South Carolina, USA, and colleagues report how 30 people with MS given 80 mg simvastatin daily for 6 months had a 44% reduction in the proportion of brain lesions after three months of treatment compared with lesions identified before treatment initiation.

Dr Singh comments: "These findings suggest that an 80 mg daily dose of oral simvastatin over a 6 month period could inhibit the inflammatory components of multiple sclerosis that lead to neurological disabilityOur results, combined with the published work on the immunological effects of statins lend support to the case for randomised controlled clinical trials to establish the safety and efficacy of statins in the treatment of relapsing-remitting multiple sclerosis".

In an accompanying Commentary (p 1570), Chris Polman from VU Medical Centre, Amsterdam, Netherlands, concludes: "[this] study is a big step forward because it is the first to provide some evidence of an effect with a statin in multiple sclerosis-but it is only an initial step. Additional data are required to more precisely determine the clinical effects of statins, to explore the optimum dose, the therapeutic window, and the differential potency of statins, and to evaluate whether combination therapy might be more effective than monotherapy. Physicians, scientists, drug companies, and regulatory agencies should now work together to design and do randomised studies that have adequate power to address these and other important issues. It is the joint responsibility of all involved to ensure that some
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-May-2004


Page: 1 2

Related medicine news :

1. Statins effective in long term, Nordic study suggests
2. Statins and aspirin may protect against severe vision loss in elderly
3. Statins could reduce stroke risk by a third
4. Statins may inhibit calcium growth on aortic valve in the elderly
5. International Study Finds Statins Raise Good Cholesterol, Wake Forest Physician Reports
6. New marker for early diagnosis of kidney failure identified
7. English-speaking Hispanic youth more likely to have sex early
8. Inpatient smoking cessation counseling is associated with early differences in mortality
9. Study finds no reason for expectant mothers to shy away from early epidurals
10. No increase in C-sections when epidural analgesia given early in labor
11. Radiologists offer non-surgical treatment for early-stage liver cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... (PRWEB) , ... May 03, 2016 , ... ... of its FDA approved sSOIP telemedicine stethoscope software that enables the stethoscope stream ... is called PCP-SSP and works with RNK’s flagship PCP-USB stethoscope. , Remote auscultation ...
(Date:5/2/2016)... (PRWEB) , ... May 02, 2016 , ... ... at a residential inpatient rehabilitation center can find some useful information in a ... located in Central Michigan. This video, which can be viewed on the Serenity ...
(Date:5/2/2016)... ... 02, 2016 , ... The Beryl Institute announces the publication ... international, open access, peer-reviewed journal focused on research and proven practices around understanding ... authors, the third volume of PXJ continues to expand PXJ's reach both with ...
(Date:5/2/2016)... ... May 02, 2016 , ... Pets bring laughter, joy and love ... pet owners celebrate National Pet Week, which falls on the first full week of ... to cherish the human-animal bond and recognize responsible pet ownership. Pet owners can live ...
(Date:5/2/2016)... Houston, Texas (PRWEB) , ... May 02, 2016 , ... ... as a time to honor the civilian nurses that care for its uniformed service ... Nixon signed a proclamation in 1974 designating May 6th through May 12th National Nurses ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... 2016 Norgine B.V. ... einen entscheidenden Meilenstein durch diese Veröffentlichung zur  ... Handeln, um Patientenresultate  bei Verdauungs- und Lebererkrankungen ... im Verständnis der Hepatischen Enzephalopathie bei und ... Hepatische Enzephalopathie in der Öffentlichkeit zu schaffen ...
(Date:5/2/2016)... -- Leading Economies with Fastest Real GDP Annual Percentage Change, 2015  ... Ireland 7.8 India 7.3, , Source: IMF and TechSci Research ... of Brazil , Russia , ... , registered the fastest GDP growth during the first decade of the ... recession in Brazil and Russia , ...
(Date:5/2/2016)...  While nearly three-quarters of Americans (71%) are aware ... health, only about half report taking any steps to ... a new survey announced today by Hologic (Nasdaq: ... Osteoporosis Month, Hologic is raising awareness of this major ... Americans. Osteoporosis is a disease that causes ...
Breaking Medicine Technology:
Cached News: