HOME >> MEDICINE >> NEWS
Statins show early promise for treating multiple sclerosis

Results of a preliminary study in this week's issue of THE LANCET suggest that statins (cholesterol-lowering drugs) could have potential in the treatment of multiple sclerosis (MS).

Drug treatments for MS are expensive and only partially effective. Recent knowledge that statins promote an anti-inflammatory response from the immune system suggest a potential in the treatment of MS.

Inderjit Singh from the Medical University of South Carolina, USA, and colleagues report how 30 people with MS given 80 mg simvastatin daily for 6 months had a 44% reduction in the proportion of brain lesions after three months of treatment compared with lesions identified before treatment initiation.

Dr Singh comments: "These findings suggest that an 80 mg daily dose of oral simvastatin over a 6 month period could inhibit the inflammatory components of multiple sclerosis that lead to neurological disabilityOur results, combined with the published work on the immunological effects of statins lend support to the case for randomised controlled clinical trials to establish the safety and efficacy of statins in the treatment of relapsing-remitting multiple sclerosis".

In an accompanying Commentary (p 1570), Chris Polman from VU Medical Centre, Amsterdam, Netherlands, concludes: "[this] study is a big step forward because it is the first to provide some evidence of an effect with a statin in multiple sclerosis-but it is only an initial step. Additional data are required to more precisely determine the clinical effects of statins, to explore the optimum dose, the therapeutic window, and the differential potency of statins, and to evaluate whether combination therapy might be more effective than monotherapy. Physicians, scientists, drug companies, and regulatory agencies should now work together to design and do randomised studies that have adequate power to address these and other important issues. It is the joint responsibility of all involved to ensure that some
'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-May-2004


Page: 1 2

Related medicine news :

1. Statins effective in long term, Nordic study suggests
2. Statins and aspirin may protect against severe vision loss in elderly
3. Statins could reduce stroke risk by a third
4. Statins may inhibit calcium growth on aortic valve in the elderly
5. International Study Finds Statins Raise Good Cholesterol, Wake Forest Physician Reports
6. New marker for early diagnosis of kidney failure identified
7. English-speaking Hispanic youth more likely to have sex early
8. Inpatient smoking cessation counseling is associated with early differences in mortality
9. Study finds no reason for expectant mothers to shy away from early epidurals
10. No increase in C-sections when epidural analgesia given early in labor
11. Radiologists offer non-surgical treatment for early-stage liver cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the Law ... organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps our ... a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... , ... October 13, 2017 , ... The Visiting Nurse ... Market. Featuring a collection of specialty vendors and unique items from across the nation, ... quality-focused health and wellness services offered by the VNA. The boutique will be ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and ... explains one of the most popular and least understood books in the Holy Scriptures, ... puzzling descriptions that have baffled scholars for centuries. Many have tossed it off as ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains ... possible to save lost souls in the Philippines. “The Journey: From the Mountains to ... dedicated teacher of the Bible. She has taught all ages and currently teaches a ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and ... apnea using cutting-edge Oventus O2Vent technology. As many as 18 million Americans ... frequent cessation in breathing. Oral appliances can offer significant relief to about 75 ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Divoti USA will engrave and process all non-coated ... latest FDA requirements, which stipulates new criteria regarding medical device manufacture ... Medical ID jewelry such as Medical ID Bracelets, can rest assured ... of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving process ...
(Date:10/11/2017)... Oct. 11, 2017  True Health, a leader ... its effort during National Breast Cancer Awareness month ... risks. Research ... calculated that more than 10 million American women ... in BRCA1 or BRCA2 and have not had testing. ...
(Date:10/7/2017)... 2017   Provista, a proven leader in ... in purchasing power, today announced a new resource area ... Newsroom is the online home for case studies, ... bios, news releases, slideshows and events. ... of resources at their fingertips, viewers can also watch ...
Breaking Medicine Technology:
Cached News: