Stiffness of aorta predicts stroke deaths in hypertensive patients

DALLAS, April 4 For the first time, researchers have linked the stiffness of the aorta (the major artery that carries blood from the heart to the rest of the body) to fatal stroke regardless of other stroke risk factors, according to a study in today's rapid access issue of Stroke: Journal of the American Heart Association.

Aging, environmental and genetic factors decrease the elasticity of arterial walls. This increased stiffness leads to elevated blood pressure.

Researchers from Hpital Europen Georges Pompidou in Paris followed 1,715 patients with mild hypertension, but without overt signs of cardiovascular disease, for an average of 7.9 years. Each participant had some degree of arterial stiffness. Arterial stiffness was gauged by measuring how long it took a pulse wave to move from the heart to other parts of the body (pulse wave velocity or PWV). Stiffer arteries had higher PWV numbers. There were 157 deaths, including 25 from strokes and 35 from coronary events.

Researchers calculated the relative risk for fatal stroke compared to PWV. They found a 72 percent increase in relative risk for fatal stroke for each four meters per second in PWV. That's "equivalent to seven years of aging," says lead author Stphane Laurent, M.D.

The predictive value of PWV remained significant after adjusting for classic cardiovascular risk factors including age, elevated cholesterol, diabetes, smoking and high blood pressure.

Several mechanisms may explain the association. Aortic stiffness may increase pulse pressure (the difference between the upper and lower numbers in a blood pressure reading) thereby increasing the likelihood of heart disease and stroke; or the stiffness measurement may reflect damage in the artery wall, Laurent says.

Researchers conclude that aortic stiffness can gauge the fatal stroke risk of hypertensive patients. However, large clinical trials using antihypertensive drugs that relieve arteria

Contact: Carole Bullock
American Heart Association

Page: 1 2

Related medicine news :

1. Uninsured face higher death risk from aorta problems
2. Study: Ripped aortas kill often, but new knowledge may aid survival
3. New evaluation tool reliably predicts recovery from coma
4. New scale predicts recovery of consciousness from coma after brain injury
5. Computational tool predicts how drugs work in cells, advancing efforts to design better medicines
6. Depression predicts heart rhythm abnormalities in heart attack patients
7. A shallow hip socket predicts osteoarthritis of the hip
8. Molecule predicts colon cancer patient survival
9. Substance in urine predicts development of preeclampsia
10. Blood protein predicts risk of heart attack
11. Molecular test predicts risk of breast cancer recurrence and who will benefit from chemotherapy

Post Your Comments:

(Date:9/3/2020)... ... September 03, 2020 , ... The ... the focus of Fall 2020 Virtual Conference, a two-day virtual event for radiology ... Imaging & Beyond" is the follow-up to AuntMinnie.com's successful virtual event in spring ...
(Date:9/3/2020)... ... September 03, 2020 , ... International Dark-Sky Association (IDA) ... parking lot controller. This advanced LED wireless dimming controller, along with the previously ... the night sky against light pollution. Leo Smith, the Northeast Regional Director for ...
(Date:9/1/2020)... ... September 01, 2020 , ... KitoTech Medical, ... convertible note financing, which will be used to accelerate the commercialization of its ... financing, the company will continue to expand its customer base of healthcare systems ...
(Date:9/1/2020)... ... September 01, 2020 , ... Dr. Kiran Gill is ... surgery of the face, breast, and body. In 2018, she founded Aesthetics in ... surgery and aesthetic practice in Southwest Florida. Dr. Gill and her team offer ...
(Date:8/31/2020)... ... ... your dear friend has cancer? , It’s hard to hear your doctor say the words ... the shock wears off, the questions and fears can be overwhelming. , How should I ... Words are failing me. I’m scared. I want to DO something. , We’ve talked to ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... 28, 2020 , ... Cano Health, LLC, a leading population ... San Antonio is happy to announce that it has selected Tejano musician Jay ... he will serve as community advisor, advertising talent, and creative consultant for Cano ...
(Date:8/27/2020)... ... August 27, 2020 , ... The flu season is right round the corner and the ... with all the necessary measures before it begins to harbor its effects on us. Already ... is leaving a huge impact on our lives. Hence it has become even more relevant ...
(Date:8/26/2020)... ... 26, 2020 , ... ScripHessco has announced the release of ... down ways that chiropractors can help heal sports injuries and get athletes on ... an unusual amount of pressure and stress on their bodies, so checkups to ...
Breaking Medicine Technology:
Cached News: