Student identifies electrical changes preceding heart failure

A Johns Hopkins undergraduate student has contributed to new research showing that electrical changes in the heart leading to heart failure can occur long before a patient exhibits any clinical symptoms. The initial changes can then spur a second, later phase of changes that cause lethal heart rhythm disturbances known as arrhythmias.

The study by Samuel Hahn, 21, a senior biomedical engineering major from Lutherville, Md.; and Fadi G. Akar, Ph.D., a research assistant professor at the Johns Hopkins School of Medicine, was the first to describe the time-course and nature of electrical abnormalities occurring during the development of heart failure. A manuscript of their work has been submitted to a peer-reviewed scientific journal. The two conducted their research in the laboratory of Gordon F. Tomaselli, professor of medicine and vice chair for research in the Department of Medicine.

"By the time most patients are diagnosed with heart failure, it's too late to really improve their condition," Akar said. "By defining the early electrical changes, we hope to identify new targets for therapy that can either reverse or, at the very least, hinder the progression of the vicious cycle of events that ultimately leads to death."

During heart failure, the pumping action of the heart becomes inadequate, resulting in a back pressure of blood along with congestion of the lungs and liver. Nearly 5 million Americans suffer from heart failure and more than 250,000 die annually from the condition, Hahn said. The incidence and prevalence of the disease continue to increase with the aging of the U.S. population.

"Despite remarkable improvements in medical therapy, the prognosis of patients with heart failure remains very poor, with almost 20 percent of patients dying within one year of initial diagnosis, and over 80 percent within eight years," Hahn said. "Of the deaths in patients with heart failure, up to 50 percent are sudden and unexpected, and

Contact: Phil Sneiderman
Johns Hopkins University

Page: 1 2 3

Related medicine news :

1. Student nurses need better understanding of poverty-stricken patients
2. Student builds micro biosensor chip to move DNA molecules
3. Students of mixed races report suffering more health problems
4. Students eat excessive amounts of fat at school
5. Students join scientists in search of asthma triggers
6. Students invent voice-activated grasping tool for disabled man
7. Students demonstrate water quality tests
8. Students Show Restraint Could Cut School Bus Injuries
9. From Cow Brains To Surgical Scrubs: Selected Students Will Get A Close-Up Look At Neurosurgery At Brainworks
10. Teen Line Panel Of Six High School Students To Address The Issue Of Teens And Tolerance
11. Temples Virtual Lab Helps Disabled Students

Post Your Comments:

(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... As a ... Magna Cum Laude and his M.D from the David Geffen School of Medicine at ... returned to Los Angeles to complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars ...
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published June ... with. The article goes on to state that individuals are now more comfortable seeking ... common operations such as calf and cheek reduction. The Los Angeles area medical group, ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
(Date:6/24/2016)... Rhinebeck, NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of ... of companies that call for a minimum wage raise to $12 an hour by 2020 ... wage. This will restore the lost value of the minimum wage, assure the wage floor ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Grove Investment Group (TGIG), has initiated cultivation and processing operations at its production ... and Pahrump, Nevada. , Puradigm is the manufacturer of a complete system of ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
(Date:6/23/2016)... and INDIANAPOLIS , June ... receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship is any ... scholarship winners, announced today online at www.diabetesscholars.org ... type 1 diabetes stand in the way of academic ... supported the Foundation,s scholarship program since 2012, and continues ...
(Date:6/23/2016)... June 23, 2016 Revolutionary technology ... Oticon , industry leaders in advanced audiology and ... Oticon Opn ™, the world,s first internet connected ... for IoT devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ... a number of ,world firsts,: , TwinLink™ ...
Breaking Medicine Technology:
Cached News: