HOME >> MEDICINE >> NEWS
Studies on statin use and fracture risk show mixed results

CHICAGO A review of previous studies suggests a possible benefit of statin drugs for reducing the risk of bone fracture in older women, although further research is needed to examine this question, according to an article in the January 26 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

According to the article, statins are widely used to treat high cholesterol, but little information is available about the effects of statins on bone. Some retrospective studies have found that statin use is associated with a reduced risk for fracture, and other studies suggest that bone mass is higher in people taking statin medications.

Douglas C. Bauer, M.D., from the University of California, San Francisco, and colleagues investigated whether statin use is associated with a reduced risk for bone fracture. The researchers analyzed combined data on statin use and fracture rates from four large prospective studies of older women (the Study of Osteoporotic Fractures, the Fracture Intervention Trial, the Heart and Estrogen/Progestin Replacement Study, and the Rotterdam Study). They also summarized the results of eight observational studies and two clinical trials (found by searching English-language medical literature through January 2002) that reported statin use and documented fractures.

Statin use ranged from less than 1 percent of participants in the Rotterdam Study, to greater than 26 percent in the Heart and Estrogen/Progestin Replacement Study. After the researchers adjusted data to take into account age, body mass index, and estrogen use, they found that there was a trend towards fewer hip fractures (38 percent to 81 percent lower risk) and to a lesser extent, nonspine fractures (5 percent to 51 percent lower risk) among statin users in each of the four large studies. The researchers' analysis of the observational studies was consistent with these findings, with an estimated 57 percent reduction in hip fractur
'"/>

Contact: Eve Harris
415-885-7277
JAMA and Archives Journals
26-Jan-2004


Page: 1 2

Related medicine news :

1. Studies underscore genetic involvement in nicotine addiction & aggressive hostility
2. Studies address issues of risk and survival in rapidly increasing GI cancers
3. Studies examine coffee drinking and risk of liver and colorectal cancers
4. Studies reveal physicians attitudes on end-of-life care
5. Studies from the November issue of The Archives of Dermatology, a theme issue on facial rejuvenation
6. Studies link obesity to increased frequency of heartburn symptoms; greater risk of esophageal cancer
7. Studies demonstrate positive data in treatment of hepatitis C
8. Studies examine risk factors and potential consequences associated with prehypertension
9. Studies show ACTOS(R) (pioglitazone HCl) has positive effects on various components of dyslipidemia
10. Studies identify risk factors for colon cancer
11. Studies indicate healthy eating may affect cancer development, improve digestive system

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2019)... ... May 16, 2019 , ... Prominent pianist Paul Cardall will ... Franklin Theatre on May 22. Ballard founded O.U.R. in 2013 as the leading organization ... a former Department of Homeland Security Special Agent, leads a team of former CIA, ...
(Date:5/16/2019)... ... May 16, 2019 , ... AdventHealth West Florida Division announced ... in Tampa Bay. Today, the prestigious Leapfrog Group, a national nonprofit health care ... Only about a third of those hospitals received an “A” grade, including seven ...
(Date:5/15/2019)... ... May 16, 2019 , ... Statistical Concepts ... p.m. - 3:00 p.m. EDT, https://www.fdanews.com/statisticalconceptsprocessvalidation , Devicemakers: Are the organizations ... or even maybe … Dan O’Leary is here to help. Dan is FDAnews’s ...
(Date:5/14/2019)... ... ... in Wednesday, May 15 at 7pm for the Healthy Woman Show on WJR 760AM radio ... problems that are embarrassing and inconvenient for women. , “We know how bladder control ... time away from your home. Our goal is to help you stop leaking so ...
(Date:5/14/2019)... ... 2019 , ... The Atlanta Falcons, the Baltimore Ravens and ... the U.S. who rely on HydroWorx aquatic therapy pools to care for their ... healing,” said Timothy McCarthy, Chief Executive Officer for HydroWorx. “Whether it’s for ...
Breaking Medicine News(10 mins):
(Date:5/15/2019)... , ... May 15, 2019 , ... ... announce Gaston County’s success thanks to the Stratodesk/ViewSonic SC-T25 Citrix Ready workspace hub. ... of the joint solution in order to deliver advanced endpoint computing to their ...
(Date:5/15/2019)... ... May 15, 2019 , ... PAINWeekEnd on ... in Rhode Island, will be an educational and exciting program providing busy clinicians ... management of chronic pain. , In Rhode Island, updated regulations intended to ...
(Date:5/15/2019)... PLAINS, N.J. (PRWEB) , ... May 15, 2019 , ... ... her for. Her goal is to help patients achieve optimal dental health while addressing ... excellent care at her office in Cresskill, New Jersey. She offers both general dentistry ...
Breaking Medicine Technology:
Cached News: