HOME >> MEDICINE >> NEWS
Studies show ACTOS(R) (pioglitazone HCl) has positive effects on various components of dyslipidemia

Orlando, FL, June 5, 2004 Two clinical studies presented at the American Diabetes Association's (ADA) Scientific Sessions showed that ACTOS (pioglitazone HCl) has favorable effects on dyslipidemia (low HDL-C levels, high triglycerides and high levels of small, dense LDL-C) and insulin resistance. Dyslipidemia and insulin resistance are two key components of the metabolic syndrome, which is often exhibited in patients with type 2 diabetes.

"When you put the pieces together, these separate findings are very exciting because they show that ACTOS therapy can provide benefits extending beyond improvements in glucose levels," said Mehmood Khan, M.D., F.A.C.E., senior vice president for medical and scientific affairs, Takeda Pharmaceuticals. "These studies showed that ACTOS can affect certain components of the metabolic syndrome, each of which must be managed when treating people with type 2 diabetes. We now have reason to believe that, when a physician prescribes ACTOS for type 2 diabetes, the patient may also benefit from a reduction of other risk factors."

Results of a pooled analysis of four separate, double-blind, randomized, multi-center trials conducted over the course of one year demonstrated that ACTOS has favorable effects on dyslipidemia in patients with type 2 diabetes. In each of the four trials, patients with poorly controlled type 2 diabetes were randomized to receive monotherapy consisting of ACTOS, metformin or a sulfonylurea (gliclazide), or a combination of ACTOS with these two agents.

Analysis of the data showed that, in addition to reducing hyperglycemia by addressing insulin resistance, ACTOS alone, or in combination with either metformin or the sulfonylurea, brought about a statistically significant decrease in serum triglycerides from baseline, and a statistically significant increase in HDL ("good") cholesterol, versus either of the other drugs alone or in combination with each other.

Additionally, statisticall
'"/>

Contact: Julio Cantre
julio.cantre@ketchum.com
646-935-4122
Ketchum
6-Jun-2004


Page: 1 2 3

Related medicine news :

1. Studies underscore genetic involvement in nicotine addiction & aggressive hostility
2. Studies address issues of risk and survival in rapidly increasing GI cancers
3. Studies examine coffee drinking and risk of liver and colorectal cancers
4. Studies reveal physicians attitudes on end-of-life care
5. Studies from the November issue of The Archives of Dermatology, a theme issue on facial rejuvenation
6. Studies link obesity to increased frequency of heartburn symptoms; greater risk of esophageal cancer
7. Studies demonstrate positive data in treatment of hepatitis C
8. Studies examine risk factors and potential consequences associated with prehypertension
9. Studies identify risk factors for colon cancer
10. Studies indicate healthy eating may affect cancer development, improve digestive system
11. Studies compare hysterectomy vs. other medical treatments for abnormal uterine bleeding

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2020)... ... May 15, 2020 , ... KUDO Inc., ... the Open Source Medical Supplies (OSMS). The organization will obtain free access to ... the spread of COVID-19. , Created as a response to the COVID-19 pandemic ...
(Date:5/15/2020)... , ... May 15, 2020 , ... COVID-19 has made ... their feet by making sure their employees can get back to work safely. Their ... have expanded to gyms, restaurants, bars, and countless other settings. , Everyone needs to ...
(Date:5/15/2020)... ... May 15, 2020 , ... ... recently announced the company and its healthcare-focused background screening division, PreCheck, were both ... Screening Consulting/Services Companies 2020. A distinguished panel comprising of CEOs, CIOs, CHROs, and ...
(Date:5/15/2020)... ... May 15, 2020 , ... As businesses prepare to reopen, preventative ... is a need to combat the spread of the virus in a way that ... hopes to help with their TempCheck Sentinel and TempCheckplus Sentry no-contact infrared temperature sensing ...
(Date:5/15/2020)... , ... May 15, 2020 , ... How do you ... unanswered. Thousands of private practice offices are not set up to see their patients. ... patient and disease history are challenging to overcome. Doctors and patients need to connect ...
Breaking Medicine News(10 mins):
(Date:5/17/2020)... ... May 17, 2020 , ... CyberMaxx™ has received ... Insyte CPAs, LLC, an independent service auditor. This certification illustrates CyberMaxx's constant dedication ... can rely. , "It was a pleasure to work with the CyberMaxx team ...
(Date:5/16/2020)... HARRISBURG, Pa. (PRWEB) , ... ... ... are licensed allied healthcare professionals, who in collaboration with a physician, can ... care, examination and clinical diagnosis, therapeutic intervention, and rehabilitation of injuries and ...
(Date:5/16/2020)... , ... May 15, 2020 , ... ... medicine to treat fatigue, impotence, constipation, frequent urination and joint pain, but have ... possess the ability to boost the immune system , naturally. , Sea ...
Breaking Medicine Technology:
Cached News: