Studies underscore genetic involvement in nicotine addiction & aggressive hostility

ecific components of aggression in 58 participants appeared to relate to the U allele (variation) of a gene called TPH (tryptophan hydroxylase), a marker that might be linked to another yet unknown gene with specific and functional aspects. Says Hennig, "Linkage means that both genes are transmitted together due to their being close neighbors on the same chromosome."

The researchers measured genotypes dubbed AA, AC and CC. The "AA" genotype was associated with the highest levels of aggression, whereas the "CC" genotype was associated with lowest levels.

Using another sample of 48 men, the authors also validated the distinction between irritable, verbally abusive "neurotic hostility" and more violent, guilt-free "aggressive hostility" found in the Buss-Durkee Hostility Inventory, a research tool used worldwide. The authors say that their finding underscores the value of distinguishing among different aspects of aggression.

Finally, only the "aggressively hostile" men released high levels of cortisol, a key stress-hormone, after taking an anti-depressant drug that makes serotonin more available in the brain. The authors speculate that, after being deprived of serotonin, these men's neural receptors were exquisitely sensitive and primed to over-react, in part by producing extra cortisol.

Tying together the three findings, Hennig concludes that, "We found that gene polymorphisms contribute to the variance that can be found in neuro-endocrine challenge tests and personality questionnaires in healthy individuals. This demonstrates that certain aspects of behavior relate to biological systems, such as neurotransmitter systems."


Contact: APA Public Affairs Office
American Psychological Association

Page: 1 2 3

Related medicine news :

1. Studies address issues of risk and survival in rapidly increasing GI cancers
2. Studies examine coffee drinking and risk of liver and colorectal cancers
3. Studies reveal physicians attitudes on end-of-life care
4. Studies from the November issue of The Archives of Dermatology, a theme issue on facial rejuvenation
5. Studies link obesity to increased frequency of heartburn symptoms; greater risk of esophageal cancer
6. Studies demonstrate positive data in treatment of hepatitis C
7. Studies examine risk factors and potential consequences associated with prehypertension
8. Studies show ACTOS(R) (pioglitazone HCl) has positive effects on various components of dyslipidemia
9. Studies identify risk factors for colon cancer
10. Studies indicate healthy eating may affect cancer development, improve digestive system
11. Studies compare hysterectomy vs. other medical treatments for abnormal uterine bleeding

Post Your Comments:

(Date:12/9/2019)... ... 2019 , ... Representatives with Vigorous Innovations announced today that it ... for Christmas. , “We’re very excited about the launched of the VI PRO Mini ... “The new massage gun can eliminate the fatigue of the day and relieve the ...
(Date:12/9/2019)... , ... December 09, 2019 , ... ... Pain Institute, Presidential Appointee U.S. Department of Health and Human Services' (HHS) Pain ... the sixth annual 2019 Summit on Balance Pain Management in Washington DC. , ...
(Date:12/9/2019)... ... December 09, 2019 , ... WEDI , the nation’s ... care information exchange and a trusted advisor to the U.S. Department of Health and ... Board of Directors, election of Officers* as well as the re-election of ten previous ...
(Date:12/9/2019)... INDIANAPOLIS (PRWEB) , ... December 09, 2019 , ... ... medical device companies, today announced new updates to the platform’s - - ... in customers’ ability to identify, assess, and track the items impacted by change ...
(Date:12/9/2019)... ... December 09, 2019 , ... ... that help food and manufacturing companies engage with their workforces to drive ... solution helps manufacturers build a cohesive culture that is designed to protect ...
Breaking Medicine News(10 mins):
(Date:12/9/2019)... ... December 09, 2019 , ... Hawaii Health ... farm-to-state program championed by State Senate President Ronald Kouchi. As part of the ... markets for local farmers. In addition to local food sourcing, the initiative will ...
(Date:12/9/2019)... Calif. (PRWEB) , ... December 09, 2019 , ... ... solutions to optimize healthcare provider savings across purchased services contracts, today announced its ... healthcare provider in San Diego County with four acute care hospitals, three specialty ...
(Date:12/9/2019)... ... December 09, 2019 , ... American Pharmaceutical Review, the ... has released its documentary on " Making Data Work: Leveraging Data for Better ... are currently using data to produce products, and how they can leverage the ...
Breaking Medicine Technology:
Cached News: